Ory, Daniel S.

In Vivo Gene Delivery and Stable Transduction of Nondividing Cells by a Lentiviral Vector

Naldini, L., Blömer, U., Gallay, P., Ory, D., Mulligan, R., Gage, F. H., Verma, I. M., & Trono, D. (1996) · Science

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 4,903

Triglyceride accumulation protects against fatty acid-induced lipotoxicity

Listenberger, L. L., Han, X., Lewis, S. E., Cases, S., Farese, R. V., Ory, D. S., & Schaffer, J. E. (2003) · Proceedings of the National Academy of Sciences

Lipid metabolism and biosynthesisLipid metabolism and disorders

Cited by 2,075

miR-33 links SREBP-2 induction to repression of sterol transporters

Marquart, T. J., Allen, R. M., Ory, D. S., & Baldán, Á. (2010) · Proceedings of the National Academy of Sciences

Cholesterol and Lipid MetabolismMicroRNA in disease regulation

Cited by 562

Lysosomal cholesterol activates mTORC1 via an SLC38A9–Niemann-Pick C1 signaling complex

Castellano, B. M., Thelen, A. M., Moldavski, O., Feltes, M., van der Welle, R. E. N., Mydock-McGrane, L., Jiang, X., van Eijkeren, R. J., Davis, O. B., Louie, S. M., et al. (2017) · Science

PI3K/AKT/mTOR signaling in cancerAutophagy in Disease and Therapy

Cited by 562

Impaired Cholesterol Efflux in Senescent Macrophages Promotes Age-Related Macular Degeneration

Sene, A., Khan, A. A., Cox, D., Nakamura, R. E. I., Santeford, A., Kim, B. M., Sidhu, R., Onken, M. D., Harbour, J. W., Hagbi-Levi, S., et al. (2013) · Cell Metabolism

Cholesterol and Lipid MetabolismAtherosclerosis and Cardiovascular Diseases

Cited by 277

Bariatric Surgery–Induced Cardiac and Lipidomic Changes in Obesity‐Related Heart Failure with Preserved Ejection Fraction

Mikhalkova, D., Holman, S. R., Jiang, H., Saghir, M., Novak, E., Coggan, A. R., O'Connor, R., Bashir, A., Jamal, A., Ory, D. S., et al. (2018) · Obesity

Bariatric Surgery and OutcomesCardiovascular Function and Risk Factors

Cited by 121

Collaborative Development of 2-Hydroxypropyl-β-Cyclodextrin for the Treatment of Niemann-Pick Type C1 Disease

Ottinger, E., Kao, M., Carrillo-Carrasco, N., Yanjanin, N., Shankar, R., Janssen, M., Brewster, M., Scott, I., Xu, X., Cradock, J., et al. (2014) · Current Topics in Medicinal Chemistry

Lysosomal Storage Disorders ResearchGlycogen Storage Diseases and Myoclonus

Cited by 121

Macrophage microRNA-150 promotes pathological angiogenesis as seen in age-related macular degeneration

Lin, J. B., Moolani, H. V., Sene, A., Sidhu, R., Kell, P., Lin, J. B., Dong, Z., Ban, N., Ory, D. S., & Apte, R. S. (2018) · JCI Insight

Retinal Diseases and TreatmentsMicroRNA in disease regulation

Cited by 54

A novel gene editing system to treat both Tay–Sachs and sandhoff diseases

Ou, L., Przybilla, M. J., Tăbăran, A.-F., Overn, P., O’Sullivan, M. G., Jiang, X., Sidhu, R., Kell, P. J., Ory, D. S., & Whitley, C. B. (2020) · Gene Therapy

Lysosomal Storage Disorders ResearchVirus-based gene therapy research

Cited by 52

Analytical Characterization of Methyl-β-Cyclodextrin for Pharmacological Activity to Reduce Lysosomal Cholesterol Accumulation in Niemann-Pick Disease Type C1 Cells

Li, R., Hao, J., Fujiwara, H., Xu, M., Yang, S., Dai, S., Long, Y., Swaroop, M., Li, C., Vu, M., et al. (2017) · ASSAY and Drug Development Technologies

Lysosomal Storage Disorders ResearchBiomedical Research and Pathophysiology

Cited by 21