Liu, Caini

The adaptor Act1 is required for interleukin 17-dependent signaling associated with autoimmune and inflammatory disease

Qian, Y., Liu, C., Hartupee, J., Altuntas, C. Z., Gulen, M. F., Jane-wit, D., Xiao, J., Lu, Y., Giltiay, N., Liu, J., et al. (2007) · Nature Immunology

Psoriasis: Treatment and PathogenesisNF-κB Signaling Pathways

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Astrocyte-restricted ablation of interleukin-17-induced ACT1-mediated signaling ameliorates autoimmune encephalomyelitis

Kang, Z., Altuntas, C. Z., Gulen, M. F., Liu, C., Giltiay, N., Qin, H., Liu, L., Qian, W., Ransohoff, R. M., Bergmann, C., et al. (2010) · Immunity

Multiple Sclerosis Research StudiesPsoriasis: Treatment and Pathogenesis

Cited by 297

Treatment with IL-17 prolongs the half-life of chemokine CXCL1 mRNA via the adaptor TRAF5 and the splicing-regulatory factor SF2 (ASF)

Sun, D., Novotny, M., Bulek, K., Liu, C., Li, X., & Hamilton, T. (2011) · Nature Immunology

RNA Research and SplicingCytokine Signaling Pathways and Interactions

Cited by 232

Act1, a U-box E3 Ubiquitin Ligase for IL-17 Signaling

Liu, C., Qian, W., Qian, Y., Giltiay, N. V., Lu, Y., Swaidani, S., Misra, S., Deng, L., Chen, Z. J., & Li, X. (2009) · Science Signaling

NF-κB Signaling PathwaysPsoriasis: Treatment and Pathogenesis

Cited by 224

The inducible kinase IKKi is required for IL-17-dependent signaling associated with neutrophilia and pulmonary inflammation

Bulek, K., Liu, C., Swaidani, S., Wang, L., Page, R. C., Gulen, M. F., Herjan, T., Abbadi, A., Qian, W., Sun, D., et al. (2011) · Nature Immunology

NF-κB Signaling PathwaysCytokine Signaling Pathways and Interactions

Cited by 192

IL-17-receptor-associated adaptor Act1 directly stabilizes mRNAs to mediate IL-17 inflammatory signaling

Herjan, T., Hong, L., Bubenik, J., Bulek, K., Qian, W., Liu, C., Li, X., Chen, X., Yang, H., Ouyang, S., et al. (2018) · Nature Immunology

RNA Research and SplicingCytokine Signaling Pathways and Interactions

Cited by 121

IL-17R-EGFR axis links wound healing to tumorigenesis in Lrig1+ stem cells

Chen, X., Cai, G., Liu, C., Zhao, J., Gu, C., Wu, L., Hamilton, T. A., Zhang, C.-J., Ko, J., Zhu, L., et al. (2019) · Journal of Experimental Medicine

Cytokine Signaling Pathways and InteractionsPsoriasis: Treatment and Pathogenesis

Cited by 106

HuR is required for IL-17-induced Act1-mediated CXCL1 and CXCL5 mRNA stabilization

Herjan, T., Yao, P., Qian, W., Li, X., Liu, C., Bulek, K., Sun, D., Yang, W.-P., Zhu, J., He, A., et al. (2013) · The Journal of Immunology

RNA Research and SplicingCytokine Signaling Pathways and Interactions

Cited by 95

IL-17–induced HIF1α drives resistance to anti–PD-L1 via fibroblast-mediated immune exclusion

Chen, X., Zhao, J., Herjan, T., Hong, L., Liao, Y., Liu, C., Vasu, K., Wang, H., Thompson, A., Fox, P. L., et al. (2022) · Journal of Experimental Medicine

Cancer Immunotherapy and BiomarkersImmune cells in cancer

Cited by 53