Nielsen, Lars K.

Method for generation of homogeneous multicellular tumor spheroids applicable to a wide variety of cell types

Kelm, J. M., Timmins, N. E., Brown, C. J., Fussenegger, M., & Nielsen, L. K. (2003) · Biotechnology and Bioengineering

3D Printing in Biomedical ResearchCancer Cells and Metastasis

Cited by 934

MEMOTE for standardized genome-scale metabolic model testing

Lieven, C., Beber, M. E., Olivier, B. G., Bergmann, F. T., Ataman, M., Babaei, P., Bartell, J. A., Blank, L. M., Chauhan, S., Correia, K., et al. (2020) · Nature Biotechnology

Microbial Metabolic Engineering and BioproductionGene Regulatory Network Analysis

Cited by 509

Functional screening in human cardiac organoids reveals a metabolic mechanism for cardiomyocyte cell cycle arrest

Mills, R. J., Titmarsh, D. M., Koenig, X., Parker, B. L., Ryall, J. G., Quaife-Ryan, G. A., Voges, H. K., Hodson, M. P., Ferguson, C., Drowley, L., et al. (2017) · Proceedings of the National Academy of Sciences

Pluripotent Stem Cells ResearchCongenital heart defects research

Cited by 478

AraGEM, a Genome-Scale Reconstruction of the Primary Metabolic Network in Arabidopsis

de Oliveira Dal'Molin, C. G., Quek, L.-E., Palfreyman, R. W., Brumbley, S. M., & Nielsen, L. K. (2010) · Plant Physiology

Microbial Metabolic Engineering and BioproductionBioinformatics and Genomic Networks

Cited by 353

Recon 2.2: from reconstruction to model of human metabolism

Swainston, N., Smallbone, K., Hefzi, H., Dobson, P. D., Brewer, J., Hanscho, M., Zielinski, D. C., Ang, K. S., Gardiner, N. J., Gutierrez, J. M., et al. (2016) · Metabolomics

Microbial Metabolic Engineering and BioproductionBioinformatics and Genomic Networks

Cited by 285

Generation of Multicellular Tumor Spheroids by the Hanging-Drop Method

Timmins, N. E., & Nielsen, L. K. (2007) · Methods in Molecular Medicine™

Cancer Cells and Metastasis3D Printing in Biomedical Research

Cited by 241

Formulation, construction and analysis of kinetic models of metabolism: A review of modelling frameworks

Saa, P. A., & Nielsen, L. K. (2017) · Biotechnology Advances

Microbial Metabolic Engineering and BioproductionGene Regulatory Network Analysis

Cited by 166

Low carbon fuels and commodity chemicals from waste gases – systematic approach to understand energy metabolism in a model acetogen

Marcellin, E., Behrendorff, J. B., Nagaraju, S., DeTissera, S., Segovia, S., Palfreyman, R. W., Daniell, J., Licona-Cassani, C., Quek, L.-E., Speight, R., et al. (2016) · Green Chemistry

Microbial Metabolic Engineering and BioproductionBiofuel production and bioconversion

Cited by 159

HR Index-A Simple Method for the Prediction of Oxygen Uptake

WICKS, J. R., OLDRIDGE, N. B., NIELSEN, L. K., & VICKERS, C. E. (2011) · Medicine & Science in Sports & Exercise

Cardiovascular and exercise physiologyPhysical Activity and Health

Cited by 76

Do genome-scale models need exact solvers or clearer standards?

Ebrahim, A., Almaas, E., Bauer, E., Bordbar, A., Burgard, A. P., Chang, R. L., Dräger, A., Famili, I., Feist, A. M., Fleming, R. M., et al. (2015) · Molecular Systems Biology

Microbial Metabolic Engineering and BioproductionGene Regulatory Network Analysis

Cited by 57

Perfusion culture of Chinese Hamster Ovary cells for bioprocessing applications

MacDonald, M. A., Nöbel, M., Roche Recinos, D., Martínez, V. S., Schulz, B. L., Howard, C. B., Baker, K., Shave, E., Lee, Y. Y., Marcellin, E., et al. (2022) · Critical Reviews in Biotechnology

Viral Infectious Diseases and Gene Expression in InsectsProtein purification and stability

Cited by 55

Plant genome-scale reconstruction: from single cell to multi-tissue modelling and omics analyses

Gomes de Oliveira Dal’Molin, C., & Nielsen, L. K. (2018) · Current Opinion in Biotechnology

Microbial Metabolic Engineering and BioproductionBioinformatics and Genomic Networks

Cited by 35

Extracting reaction networks from databases—opening Pandora’s box

Fearnley, L. G., Davis, M. J., Ragan, M. A., & Nielsen, L. K. (2014) · Briefings in Bioinformatics

Bioinformatics and Genomic NetworksGene Regulatory Network Analysis

Cited by 9

Absolute proteome quantification in the gas-fermenting acetogen Clostridium autoethanogenum

Valgepea, K., Talbo, G., Takemori, N., Takemori, A., Ludwig, C., Mueller, A. P., Tappel, R., Köpke, M., Simpson, S. D., Nielsen, L. K., et al. (2021) · bioRxiv (Cold Spring Harbor Laboratory)

Microbial Metabolic Engineering and BioproductionBiofuel production and bioconversion

Cited by 1