Ezaki, Osamu

The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity

Yamauchi, T., Kamon, J., Waki, H., Terauchi, Y., Kubota, N., Hara, K., Mori, Y., Ide, T., Murakami, K., Tsuboyama-Kasaoka, N., et al. (2001) · Nature Medicine

Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and Metabolism

Cited by 4,915

Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation

Watanabe, M., Houten, S. M., Mataki, C., Christoffolete, M. A., Kim, B. W., Sato, H., Messaddeq, N., Harney, J. W., Ezaki, O., Kodama, T., et al. (2006) · Nature

Adipose Tissue and MetabolismDrug Transport and Resistance Mechanisms

Cited by 2,220

Adiponectin Stimulates AMP-Activated Protein Kinase in the Hypothalamus and Increases Food Intake

Kubota, N., Yano, W., Kubota, T., Yamauchi, T., Itoh, S., Kumagai, H., Kozono, H., Takamoto, I., Okamoto, S., Shiuchi, T., et al. (2007) · Cell Metabolism

Regulation of Appetite and ObesityAdipokines, Inflammation, and Metabolic Diseases

Cited by 844

Impaired insulin signaling in endothelial cells reduces insulin-induced glucose uptake by skeletal muscle

Kubota, T., Kubota, N., Kumagai, H., Yamaguchi, S., Kozono, H., Takahashi, T., Inoue, M., Itoh, S., Takamoto, I., Sasako, T., et al. (2011) · Cell Metabolism

Metabolism, Diabetes, and CancerAdipokines, Inflammation, and Metabolic Diseases

Cited by 435

Fish Oil Feeding Decreases Mature Sterol Regulatory Element-binding Protein 1 (SREBP-1) by Down-regulation of SREBP-1c mRNA in Mouse Liver

Kim, H.-J., Takahashi, M., & Ezaki, O. (1999) · Journal of Biological Chemistry

Fatty Acid Research and HealthLipid metabolism and biosynthesis

Cited by 377

PPARγ coactivator 1β/ERR ligand 1 is an ERR protein ligand, whose expression induces a high-energy expenditure and antagonizes obesity.

Kamei, Y., Ohizumi, H., Fujitani, Y., Nemoto, T., Tanaka, T., Takahashi, N., Kawada, T., Miyoshi, M., Ezaki, O., & Kakizuka, A. (2003) · Proceedings of the National Academy of Sciences

Peroxisome Proliferator-Activated ReceptorsAdipose Tissue and Metabolism

Cited by 357

High-fat diet-induced hyperglycemia and obesity in mice: differential effects of dietary oils

Ikemoto, S., Takahashi, M., Tsunoda, N., Maruyama, K., Itakura, H., & Ezaki, O. (1996) · Metabolism

Diet, Metabolism, and DiseaseFatty Acid Research and Health

Cited by 276

Insulin receptor substrate 2 plays a crucial role in β cells and the hypothalamus

Kubota, N., Terauchi, Y., Tobe, K., Yano, W., Suzuki, R., Ueki, K., Takamoto, I., Satoh, H., Maki, T., Kubota, T., et al. (2004) · Journal of Clinical Investigation

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 239

An Increase in Murine Skeletal Muscle Peroxisome Proliferator-Activated Receptor-γ Coactivator-1α (PGC-1α) mRNA in Response to Exercise Is Mediated by β-Adrenergic Receptor Activation

Miura, S., Kawanaka, K., Kai, Y., Tamura, M., Goto, M., Shiuchi, T., Minokoshi, Y., & Ezaki, O. (2007) · Endocrinology

Adipose Tissue and MetabolismPeroxisome Proliferator-Activated Receptors

Cited by 183

Overexpression of peroxisome proliferator-activated receptor γ coactivator-1α down-regulates GLUT4 mRNA in skeletal muscles.

Miura, S., Kai, Y., Ono, M., & Ezaki, O. (2003) · Journal of Biological Chemistry

Adipose Tissue and MetabolismMetabolism, Diabetes, and Cancer

Cited by 146

Overexpression of peroxisome proliferator-activated receptor γ co-activator-1α leads to muscle atrophy with depletion of ATP.

Miura, S., Tomitsuka, E., Kamei, Y., Yamazaki, T., Kai, Y., Tamura, M., Kita, K., Nishino, I., & Ezaki, O. (2006) · The American Journal of Pathology

Muscle Physiology and DisordersAdipose Tissue and Metabolism

Cited by 107

Up-regulation of SREBP-1c and lipogenic genes in skeletal muscles after exercise training

Ikeda, S., Miyazaki, H., Nakatani, T., Kai, Y., Kamei, Y., Miura, S., Tsuboyama-Kasaoka, N., & Ezaki, O. (2002) · Biochemical and Biophysical Research Communications

Adipose Tissue and MetabolismLipid metabolism and biosynthesis

Cited by 92

Localization of Exercise- and Denervation-Responsive Elements in the Mouse GLUT4 Gene

Tsunoda, N., Maruyama, K., Cooke, D. W., Lane, D. M., & Ezaki, O. (2000) · Biochemical and Biophysical Research Communications

Metabolism, Diabetes, and CancerGenomics and Chromatin Dynamics

Cited by 34

Effects of fenofibrate and its combination with lovastatin on the expression of genes involved in skeletal muscle atrophy, including FoxO1 and its targets

Ajima, H., Kai, Y., Fujimaki, J., Akashi, S., Morita, A., Ezaki, O., Kamei, Y., & Miura, S. (2021) · The Journal of Toxicological Sciences

Muscle Physiology and DisordersFOXO transcription factor regulation

Cited by 7