Park, David S.

Loss of PINK1 Function Promotes Mitophagy through Effects on Oxidative Stress and Mitochondrial Fission

Dagda, R. K., Cherra, S. J., Kulich, S. M., Tandon, A., Park, D., & Chu, C. T. (2009) · Journal of Biological Chemistry

Parkinson's Disease Mechanisms and TreatmentsAutophagy in Disease and Therapy

Cited by 954

Constitutive Nuclear Factor-κB Activity Is Required for Central Neuron Survival

Bhakar, A. L., Tannis, L.-L., Zeindler, C., Russo, M. P., Jobin, C., Park, D. S., MacPherson, S., & Barker, P. A. (2002) · The Journal of Neuroscience

NF-κB Signaling PathwaysNuclear Receptors and Signaling

Cited by 310

APAF1 is a key transcriptional target for p53 in the regulation of neuronal cell death

Fortin, A., Cregan, S. P., MacLaurin, J. G., Kushwaha, N., Hickman, E. S., Thompson, C. S., Hakim, A., Albert, P. R., Cecconi, F., Helin, K., et al. (2001) · The Journal of Cell Biology

Cell death mechanisms and regulationCancer-related Molecular Pathways

Cited by 194

Lrrk2 alleles modulate inflammation during microbial infection of mice in a sex-dependent manner

Shutinoski, B., Hakimi, M., Harmsen, I. E., Lunn, M., Rocha, J., Lengacher, N., Zhou, Y. Y., Khan, J., Nguyen, A., Hake-Volling, Q., et al. (2019) · Science Translational Medicine

Immune Response and InflammationParkinson's Disease Mechanisms and Treatments

Cited by 96

Unique Requirement for Rb/E2F3 in Neuronal Migration: Evidence for Cell Cycle-Independent Functions

McClellan, K. A., Ruzhynsky, V. A., Douda, D. N., Vanderluit, J. L., Ferguson, K. L., Chen, D., Bremner, R., Park, D. S., Leone, G., & Slack, R. S. (2007) · Molecular and Cellular Biology

Neurogenesis and neuroplasticity mechanismsDevelopmental Biology and Gene Regulation

Cited by 88

Inactivation of Pink1 Gene in Vivo Sensitizes Dopamine-producing Neurons to 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and Can Be Rescued by Autosomal Recessive Parkinson Disease Genes, Parkin or DJ-1

Haque, M. E., Mount, M. P., Safarpour, F., Abdel-Messih, E., Callaghan, S., Mazerolle, C., Kitada, T., Slack, R. S., Wallace, V., Shen, J., et al. (2012) · Journal of Biological Chemistry

Parkinson's Disease Mechanisms and TreatmentsNuclear Receptors and Signaling

Cited by 84

Caspase 3 Deficiency Rescues Peripheral Nervous System Defect in Retinoblastoma Nullizygous Mice

Simpson, M. T. W., MacLaurin, J. G., Xu, D., Ferguson, K. L., Vanderluit, J. L., Davoli, M. A., Roy, S., Nicholson, D. W., Robertson, G. S., Park, D. S., et al. (2001) · The Journal of Neuroscience

Cell death mechanisms and regulationCancer-related Molecular Pathways

Cited by 35

LRRK2(I2020T) functional genetic interactors that modify eye degeneration and dopaminergic cell loss in Drosophila

Marcogliese, P. C., Abuaish, S., Kabbach, G., Abdel-Messih, E., Seang, S., Li, G., Slack, R. S., Haque, M. E., Venderova, K., & Park, D. S. (2017) · Human Molecular Genetics

Parkinson's Disease Mechanisms and TreatmentsNuclear Receptors and Signaling

Cited by 20

Deep learning improves utility of tau PET in the study of Alzheimer's disease

Zou, J., Park, D., Johnson, A., Feng, X., Pardo, M., France, J., Tomljanovic, Z., Brickman, A. M., Devanand, D. P., Luchsinger, J. A., et al. (2021) · Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 15