Lood, Christian

Neutrophil extracellular traps enriched in oxidized mitochondrial DNA are interferogenic and contribute to lupus-like disease

Lood, C., Blanco, L. P., Purmalek, M. M., Carmona-Rivera, C., De Ravin, S. S., Smith, C. K., Malech, H. L., Ledbetter, J. A., Elkon, K. B., & Kaplan, M. J. (2016) · Nature Medicine

Neutrophil, Myeloperoxidase and Oxidative MechanismsSystemic Lupus Erythematosus Research

Cited by 1,570

Cell-Free DNA as a Biomarker in Autoimmune Rheumatic Diseases

Duvvuri, B., & Lood, C. (2019) · Frontiers in Immunology

Systemic Lupus Erythematosus ResearchNeutrophil, Myeloperoxidase and Oxidative Mechanisms

Cited by 282

Platelets release mitochondrial antigens in systemic lupus erythematosus

Melki, I., Allaeys, I., Tessandier, N., Lévesque, T., Cloutier, N., Laroche, A., Vernoux, N., Becker, Y., Benk-Fortin, H., Zufferey, A., et al. (2021) · Science Translational Medicine

Systemic Lupus Erythematosus ResearchPlatelet Disorders and Treatments

Cited by 125

Calpain drives pyroptotic vimentin cleavage, intermediate filament loss, and cell rupture that mediates immunostimulation

Davis, M. A., Fairgrieve, M. R., Den Hartigh, A., Yakovenko, O., Duvvuri, B., Lood, C., Thomas, W. E., Fink, S. L., & Gale, M. (2019) · Proceedings of the National Academy of Sciences

Inflammasome and immune disordersCalpain Protease Function and Regulation

Cited by 104

The role of mitochondria in rheumatic diseases

Becker, Y. L. C., Duvvuri, B., Fortin, P. R., Lood, C., & Boilard, E. (2022) · Nature Reviews Rheumatology

Systemic Lupus Erythematosus ResearchMitochondrial Function and Pathology

Cited by 81

Beyond apoptosis in lupus

Colonna, L., Lood, C., & Elkon, K. B. (2014) · Current Opinion in Rheumatology

Systemic Lupus Erythematosus ResearchCell death mechanisms and regulation

Cited by 69

Mitochondrial N-formyl methionine peptides associate with disease activity as well as contribute to neutrophil activation in patients with rheumatoid arthritis

Duvvuri, B., Baddour, A. A., Deane, K. D., Feser, M. L., Nelson, J. L., Demoruelle, M. K., & Lood, C. (2021) · Journal of Autoimmunity

Rheumatoid Arthritis Research and TherapiesNatural Compounds in Disease Treatment

Cited by 58

High Prevalence and Disease Correlation of Autoantibodies Against p40 Encoded by Long Interspersed Nuclear Elements in Systemic Lupus Erythematosus

Carter, V., LaCava, J., Taylor, M. S., Liang, S. Y., Mustelin, C., Ukadike, K. C., Bengtsson, A., Lood, C., & Mustelin, T. (2020) · Arthritis & Rheumatology

Systemic Lupus Erythematosus ResearchSystemic Sclerosis and Related Diseases

Cited by 41

Prediction of Erosive Disease Development by Antimitochondrial Antibodies in Rheumatoid Arthritis

Moore, R. E., Wang, T., Duvvuri, B., Feser, M. L., Deane, K. D., Solomon, J. J., Nelson, J. L., Demoruelle, M. K., & Lood, C. (2023) · Arthritis & Rheumatology

Rheumatoid Arthritis Research and TherapiesSystemic Lupus Erythematosus Research

Cited by 15

Antimitochondrial antibodies in systemic lupus erythematosus are associated with and predict nephritis, arterial vascular events, and mortality

Becker, Y. L. C., Boilard, É., Rollet-Labelle, E., Lood, C., Julien, A.-S., Abrahamowicz, M., Allaeys, I., Choi, M., Leclerc, J., Lévesque, T., et al. (2026) · Annals of the Rheumatic Diseases

Systemic Lupus Erythematosus ResearchSystemic Sclerosis and Related Diseases

Cited by 3

Mitochondrial‐Mediated Platelet Activation in Polymyalgia Rheumatica

Michailidou, D., Johansson, L., Chapa, J. A. G., Wang, T., Chen, J., López, J. A., Rantapää‐Dahlqvist, S., & Lood, C. (2025) · ACR Open Rheumatology

Vasculitis and related conditionsPlatelet Disorders and Treatments

Cited by 3