Williams, Anna

M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination

Miron, V. E., Boyd, A., Zhao, J.-W., Yuen, T. J., Ruckh, J. M., Shadrach, J. L., van Wijngaarden, P., Wagers, A. J., Williams, A., Franklin, R. J. M., et al. (2013) · Nature Neuroscience

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 1,777

Altered human oligodendrocyte heterogeneity in multiple sclerosis

Jäkel, S., Agirre, E., Mendanha Falcão, A., van Bruggen, D., Lee, K. W., Knuesel, I., Malhotra, D., ffrench-Constant, C., Williams, A., & Castelo-Branco, G. (2019) · Nature

Multiple Sclerosis Research StudiesSingle-cell and spatial transcriptomics

Cited by 854

Disease-specific oligodendrocyte lineage cells arise in multiple sclerosis

Falcão, A. M., van Bruggen, D., Marques, S., Meijer, M., Jäkel, S., Agirre, E., Samudyata, Floriddia, E. M., Vanichkina, D. P., ffrench-Constant, C., et al. (2018) · Nature Medicine

Multiple Sclerosis Research StudiesNeurogenesis and neuroplasticity mechanisms

Cited by 579

Retinoid X receptor gamma signaling accelerates CNS remyelination

Huang, J. K., Jarjour, A. A., Nait Oumesmar, B., Kerninon, C., Williams, A., Krezel, W., Kagechika, H., Bauer, J., Zhao, C., Evercooren, A. B.-V., et al. (2011) · Nature Neuroscience

Neurogenesis and neuroplasticity mechanismsMultiple Sclerosis Research Studies

Cited by 547

Regulatory T cells promote myelin regeneration in the central nervous system

Dombrowski, Y., O'Hagan, T., Dittmer, M., Penalva, R., Mayoral, S. R., Bankhead, P., Fleville, S., Eleftheriadis, G., Zhao, C., Naughton, M., et al. (2017) · Nature Neuroscience

Neurogenesis and neuroplasticity mechanismsMultiple Sclerosis Research Studies

Cited by 533

Microglia regulate central nervous system myelin growth and integrity

McNamara, N. B., Munro, D. A. D., Bestard-Cuche, N., Uyeda, A., Bogie, J. F. J., Hoffmann, A., Holloway, R. K., Molina-Gonzalez, I., Askew, K. E., Mitchell, S., et al. (2023) · Nature

Neuroinflammation and Neurodegeneration MechanismsNeurogenesis and neuroplasticity mechanisms

Cited by 507

Remyelination in multiple sclerosis: From basic science to clinical translation

Lubetzki, C., Zalc, B., Williams, A., Stadelmann, C., & Stankoff, B. (2020) · The Lancet Neurology

Multiple Sclerosis Research StudiesNeurogenesis and neuroplasticity mechanisms

Cited by 350

Central nervous system regeneration is driven by microglia necroptosis and repopulation

Lloyd, A. F., Davies, C. L., Holloway, R. K., Labrak, Y., Ireland, G., Carradori, D., Dillenburg, A., Borger, E., Soong, D., Richardson, J. C., et al. (2019) · Nature Neuroscience

Neuroinflammation and Neurodegeneration MechanismsMultiple Sclerosis Research Studies

Cited by 316

Cell-type-specific cis-eQTLs in eight human brain cell types identify novel risk genes for psychiatric and neurological disorders

Bryois, J., Calini, D., Macnair, W., Foo, L., Urich, E., Ortmann, W., Iglesias, V. A., Selvaraj, S., Nutma, E., Marzin, M., et al. (2022) · Nature Neuroscience

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 311

Improving the translational hit of experimental treatments in multiple sclerosis

Vesterinen, H. M., Sena, E. S., ffrench-Constant, C., Williams, A., Chandran, S., & Macleod, M. R. (2010) · Multiple Sclerosis Journal

Multiple Sclerosis Research StudiesAnimal testing and alternatives

Cited by 182

Astrocyte-oligodendrocyte interaction regulates central nervous system regeneration

Molina-Gonzalez, I., Holloway, R. K., Jiwaji, Z., Dando, O., Kent, S. A., Emelianova, K., Lloyd, A. F., Forbes, L. H., Mahmood, A., Skripuletz, T., et al. (2023) · Nature Communications

Neurogenesis and neuroplasticity mechanismsMultiple Sclerosis Research Studies

Cited by 176

New oligodendrocytes exhibit more abundant and accurate myelin regeneration than those that survive demyelination

Neely, S. A., Williamson, J. M., Klingseisen, A., Zoupi, L., Early, J. J., Williams, A., & Lyons, D. A. (2022) · Nature Neuroscience

Multiple Sclerosis Research StudiesNeurogenesis and neuroplasticity mechanisms

Cited by 132

Interplay between Brain Pericytes and Endothelial Cells in Dementia

Procter, T. V., Williams, A., & Montagne, A. (2021) · The American Journal of Pathology

Barrier Structure and Function StudiesNeurological Disease Mechanisms and Treatments

Cited by 106

snRNA-seq stratifies multiple sclerosis patients into distinct white matter glial responses

Macnair, W., Calini, D., Agirre, E., Bryois, J., Jäkel, S., Smith, R. S., Kukanja, P., Stokar-Regenscheit, N., Ott, V., Foo, L. C., et al. (2025) · Neuron

Multiple Sclerosis Research StudiesSingle-cell and spatial transcriptomics

Cited by 88

Identification of endothelin 2 as an inflammatory factor that promotes central nervous system remyelination

Yuen, T. J., Johnson, K. R., Miron, V. E., Zhao, C., Quandt, J., Harrisingh, M. C., Swire, M., Williams, A., McFarland, H. F., Franklin, R. J. M., et al. (2013) · Brain

Multiple Sclerosis Research StudiesNeurogenesis and neuroplasticity mechanisms

Cited by 80

Activin receptors regulate the oligodendrocyte lineage in health and disease

Dillenburg, A., Ireland, G., Holloway, R. K., Davies, C. L., Evans, F. L., Swire, M., Bechler, M. E., Soong, D., Yuen, T. J., Su, G. H., et al. (2018) · Acta Neuropathologica

Neurogenesis and neuroplasticity mechanismsMultiple Sclerosis Research Studies

Cited by 75

The polarity protein Scribble regulates myelination and remyelination in the central nervous system

Jarjour, A. A., Boyd, A., Dow, L. E., Holloway, R. K., Goebbels, S., Humbert, P. O., Williams, A., & ffrench-Constant, C. (2015) · PLOS Biology

Neurogenesis and neuroplasticity mechanismsMultiple Sclerosis Research Studies

Cited by 39

CRISPR-edited human ES-derived oligodendrocyte progenitor cells improve remyelination in rodents

Wagstaff, L. J., Bestard-Cuche, N., Kaczmarek, M., Fidanza, A., McNeil, L., Franklin, R. J. M., & Williams, A. C. (2024) · Nature Communications

Multiple Sclerosis Research StudiesNeurogenesis and neuroplasticity mechanisms

Cited by 30

Protocol for assessing myelination by human iPSC-derived oligodendrocytes in Shiverer mouse ex vivo brain slice cultures

Tsarouchas, T. M., Zoupi, L., Williams, A., & Gibson, E. M. (2025) · STAR Protocols

Neurogenesis and neuroplasticity mechanismsPluripotent Stem Cells Research

Cited by 2