Bankiewicz, Krystof S.

Safety and tolerability of putaminal AADC gene therapy for Parkinson disease

Christine, C. W., Starr, P. A., Larson, P. S., Eberling, J. L., Jagust, W. J., Hawkins, R. A., VanBrocklin, H. F., Wright, J. F., Bankiewicz, K. S., & Aminoff, M. J. (2009) · Neurology

Parkinson's Disease Mechanisms and TreatmentsVirus-based gene therapy research

Cited by 445

Results from a phase I safety trial of hAADC gene therapy for Parkinson disease

Eberling, J. L., Jagust, W. J., Christine, C. W., Starr, P., Larson, P., Bankiewicz, K. S., & Aminoff, M. J. (2008) · Neurology

Virus-based gene therapy researchParkinson's Disease Mechanisms and Treatments

Cited by 370

Gene therapy for neurological disorders: progress and prospects

Deverman, B. E., Ravina, B. M., Bankiewicz, K. S., Paul, S. M., & Sah, D. W. Y. (2018) · Nature Reviews Drug Discovery

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 306

Adeno-Associated Virus Serotype 9 Transduction in the Central Nervous System of Nonhuman Primates

Samaranch, L., Salegio, E. A., San Sebastian, W., Kells, A. P., Foust, K. D., Bringas, J. R., Lamarre, C., Forsayeth, J., Kaspar, B. K., & Bankiewicz, K. S. (2012) · Human Gene Therapy

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 299

Magnetic resonance imaging–guided phase 1 trial of putaminal AADC gene therapy for Parkinson's disease

Christine, C. W., Bankiewicz, K. S., Van Laar, A. D., Richardson, R. M., Ravina, B., Kells, A. P., Boot, B., Martin, A. J., Nutt, J., Thompson, M. E., et al. (2019) · Annals of Neurology

Virus-based gene therapy researchParkinson's Disease Mechanisms and Treatments

Cited by 167

Eight Years of Clinical Improvement in MPTP-Lesioned Primates After Gene Therapy With AAV2-hAADC

Hadaczek, P., Eberling, J. L., Pivirotto, P., Bringas, J., Forsayeth, J., & Bankiewicz, K. S. (2010) · Molecular Therapy

Virus-based gene therapy researchParkinson's Disease Mechanisms and Treatments

Cited by 158

Axonal transport of adeno-associated viral vectors is serotype-dependent

Salegio, E. A., Samaranch, L., Kells, A. P., Mittermeyer, G., San Sebastian, W., Zhou, S., Beyer, J., Forsayeth, J., & Bankiewicz, K. S. (2013) · Gene Therapy

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 156

Cerebral infusion of AAV9 vector-encoding non-self proteins can elicit cell-mediated immune responses

Ciesielska, A., Hadaczek, P., Mittermeyer, G., Zhou, S., Wright, J. F., Bankiewicz, K. S., & Forsayeth, J. (2013) · Molecular Therapy

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 108

Transduction of Nonhuman Primate Brain with Adeno-Associated Virus Serotype 1: Vector Trafficking and Immune Response

Hadaczek, P., Forsayeth, J., Mirek, H., Munson, K., Bringas, J., Pivirotto, P., L McBride, J., Davidson, B. L., & Bankiewicz, K. S. (2009) · Human Gene Therapy

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 90

Safety of AADC Gene Therapy for Moderately Advanced Parkinson Disease: Three-Year Outcomes From the PD-1101 Trial

Christine, C. W., Richardson, R. M., Van Laar, A. D., Thompson, M. E., Fine, E. M., Khwaja, O. S., Li, C., Liang, G. S., Meier, A., Roberts, E. W., et al. (2022) · Neurology

Parkinson's Disease Mechanisms and TreatmentsVirus-based gene therapy research

Cited by 89

Kinetics and MR-Based Monitoring of AAV9 Vector Delivery into Cerebrospinal Fluid of Nonhuman Primates

Ohno, K., Samaranch, L., Hadaczek, P., Bringas, J. R., Allen, P. C., Sudhakar, V., Stockinger, D. E., Snieckus, C., Campagna, M. V., San Sebastian, W., et al. (2019) · Molecular Therapy - Methods & Clinical Development

Virus-based gene therapy researchCerebrospinal fluid and hydrocephalus

Cited by 85

Real-time MR imaging with Gadoteridol predicts distribution of transgenes after convection-enhanced delivery of AAV2 vectors

Su, X., Kells, A. P., Salegio, E. A., Richardson, R. M., Hadaczek, P., Beyer, J., Bringas, J., Pivirotto, P., Forsayeth, J., & Bankiewicz, K. S. (2010) · Molecular Therapy

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 82

Transgene Expression, Bioactivity, and Safety of CERE-120 (AAV2-Neurturin) Following Delivery to the Monkey Striatum

Herzog, C. D., Dass, B., Gasmi, M., Bakay, R., Stansell, J. E., Tuszynski, M., Bankiewicz, K., Chen, E.-Y., Chu, Y., Bishop, K., et al. (2008) · Molecular Therapy

Virus-based gene therapy researchParkinson's Disease Mechanisms and Treatments

Cited by 72

Adeno-associated virus type 6 is retrogradely transported in the non-human primate brain

San Sebastian, W., Samaranch, L., Heller, G., Kells, A. P., Bringas, J., Pivirotto, P., Forsayeth, J., & Bankiewicz, K. S. (2013) · Gene Therapy

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 62

Safety and tolerability of magnetic resonance imaging-guided convection-enhanced delivery of AAV2-hAADC with a novel delivery platform in nonhuman primate striatum

San Sebastian, W., Richardson, R. M., Kells, A. P., Lamarre, C., Bringas, J., Pivirotto, P., Salegio, E. A., DeArmond, S. J., Forsayeth, J., & Bankiewicz, K. S. (2012) · Human Gene Therapy

Virus-based gene therapy researchParkinson's Disease Mechanisms and Treatments

Cited by 48

Netrin-1 Interrupts Amyloid-β Amplification, Increases sAβPPα in vitro and in vivo, and Improves Cognition in a Mouse Model of Alzheimer’s Disease

Spilman, P. R., Corset, V., Gorostiza, O., Poksay, K. S., Galvan, V., Zhang, J., Rao, R., Peters-Libeu, C., Vincelette, J., McGeehan, A., et al. (2016) · Journal of Alzheimer's Disease

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 39

T2 imaging in monitoring of intraparenchymal real-time convection-enhanced delivery

Richardson, R. M., Gimenez, F., Salegio, E. A., Su, X., Bringas, J., Berger, M. S., & Bankiewicz, K. S. (2011) · Neurosurgery

Virus-based gene therapy researchBarrier Structure and Function Studies

Cited by 38

Analysis of a simulation algorithm for direct brain drug delivery

Rosenbluth, K. H., Eschermann, J. F., Mittermeyer, G., Thomson, R., Mittermeyer, S., & Bankiewicz, K. S. (2012) · NeuroImage

Barrier Structure and Function StudiesGlioma Diagnosis and Treatment

Cited by 36

Controlled dissemination of AAV vectors in the primate brain

Varenika, V., Kells, A. P., Valles, F., Hadaczek, P., Forsayeth, J., & Bankiewicz, K. S. (2009) · Progress in Brain Research

Virus-based gene therapy researchBarrier Structure and Function Studies

Cited by 33