Wahlestedt, Claes

Expression of a noncoding RNA is elevated in Alzheimer's disease and drives rapid feed-forward regulation of β-secretase

Faghihi, M. A., Modarresi, F., Khalil, A. M., Wood, D. E., Sahagan, B. G., Morgan, T. E., Finch, C. E., St. Laurent III, G., Kenny, P. J., & Wahlestedt, C. (2008) · Nature Medicine

Alzheimer's disease research and treatmentsCancer-related molecular mechanisms research

Cited by 1,416

Myogenic gene expression signature establishes that brown and white adipocytes originate from distinct cell lineages

Timmons, J. A., Wennmalm, K., Larsson, O., Walden, T. B., Lassmann, T., Petrovic, N., Hamilton, D. L., Gimeno, R. E., Wahlestedt, C., Baar, K., et al. (2007) · Proceedings of the National Academy of Sciences

Adipose Tissue and MetabolismPeroxisome Proliferator-Activated Receptors

Cited by 732

Altering the course of schizophrenia: progress and perspectives

Millan, M. J., Andrieux, A., Bartzokis, G., Cadenhead, K., Dazzan, P., Fusar-Poli, P., Gallinat, J., Giedd, J., Grayson, D. R., Heinrichs, M., et al. (2016) · Nature Reviews Drug Discovery

Schizophrenia research and treatmentMental Health and Psychiatry

Cited by 516

Leptin induces vascular permeability and synergistically stimulates angiogenesis with FGF-2 and VEGF

Cao, R., Brakenhielm, E., Wahlestedt, C., Thyberg, J., & Cao, Y. (2001) · Proceedings of the National Academy of Sciences

Angiogenesis and VEGF in CancerBarrier Structure and Function Studies

Cited by 446

Using molecular classification to predict gains in maximal aerobic capacity following endurance exercise training in humans

Timmons, J. A., Knudsen, S., Rankinen, T., Koch, L. G., Sarzynski, M., Jensen, T., Keller, P., Scheele, C., Vollaard, N. B. J., Nielsen, S., et al. (2010) · Journal of Applied Physiology

Genetics and Physical PerformanceCardiovascular and exercise physiology

Cited by 358

MicroRNA-132 dysregulation in schizophrenia has implications for both neurodevelopment and adult brain function

Miller, B. H., Zeier, Z., Xi, L., Lanz, T. A., Deng, S., Strathmann, J., Willoughby, D., Kenny, P. J., Elsworth, J. D., Lawrence, M. S., et al. (2012) · Proceedings of the National Academy of Sciences

Schizophrenia research and treatmentMicroRNA in disease regulation

Cited by 309

Personalized medicine in psychiatry: problems and promises

Ozomaro, U., Wahlestedt, C., & Nemeroff, C. B. (2013) · BMC Medicine

Treatment of Major DepressionSchizophrenia research and treatment

Cited by 270

RETRACTED: Inhibition of HDAC3 reverses Alzheimer’s disease-related pathologies in vitro and in the 3xTg-AD mouse model

Janczura, K. J., Volmar, C.-H., Sartor, G. C., Rao, S. J., Ricciardi, N. R., Lambert, G., Brothers, S. P., & Wahlestedt, C. (2018) · Proceedings of the National Academy of Sciences

Alzheimer's disease research and treatmentsHistone Deacetylase Inhibitors Research

Cited by 183

Oligonucleotide therapies for disorders of the nervous system

Khorkova, O., & Wahlestedt, C. (2017) · Nature Biotechnology

RNA Interference and Gene DeliveryBarrier Structure and Function Studies

Cited by 179

Decreased cerebrospinal fluid neuropeptide Y (NPY) in patients with treatment refractory unipolar major depression: preliminary evidence for association with preproNPY gene polymorphism

Heilig, M., Zachrisson, O., Thorsell, A., Ehnvall, A., Mottagui-Tabar, S., Sjögren, M., Åsberg, M., Ekman, R., Wahlestedt, C., & Ågren, H. (2004) · Journal of Psychiatric Research

Neuropeptides and Animal PhysiologyStress Responses and Cortisol

Cited by 177

Identification of a cancer stem cell-specific function for the histone deacetylases, HDAC1 and HDAC7, in breast and ovarian cancer

Witt, A. E., Lee, C.-W., Lee, T. I., Azzam, D. J., Wang, B., Caslini, C., Petrocca, F., Grosso, J., Jones, M., Cohick, E. B., et al. (2017) · Oncogene

Cancer Cells and MetastasisHistone Deacetylase Inhibitors Research

Cited by 172

Histone deacetylases (HDACs) and brain function

Volmar, C.-H., & Wahlestedt, C. (2015) · Neuroepigenetics

Histone Deacetylase Inhibitors ResearchEpigenetics and DNA Methylation

Cited by 151

Oxytocin and social functioning

Jones, C., Barrera, I., Brothers, S., Ring, R., & Wahlestedt, C. (2017) · Dialogues in Clinical Neuroscience

Neuroendocrine regulation and behaviorAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

Cited by 132

Altered regulation of the PINK1 locus: a link between type 2 diabetes and neurodegeneration?

Scheele, C., Nielsen, A. R., Walden, T. B., Sewell, D. A., Fischer, C. P., Brogan, R. J., Petrovic, N., Larsson, O., Tesch, P. A., Wennmalm, K., et al. (2007) · The FASEB Journal

Metabolism, Diabetes, and CancerAdipose Tissue and Metabolism

Cited by 110

Involvement of long noncoding RNAs in diseases affecting the central nervous system

Pastori, C., & Wahlestedt, C. (2012) · RNA Biology

Cancer-related molecular mechanisms researchRNA Research and Splicing

Cited by 100

Expression profiling following local muscle inactivity in humans provides new perspective on diabetes-related genes.

Timmons, J. A., Norrbom, J., Schéele, C., Thonberg, H., Wahlestedt, C., & Tesch, P. (2006) · Genomics

Adipose Tissue and MetabolismMetabolism, Diabetes, and Cancer

Cited by 79

Vitamin C Sensitizes Melanoma to BET Inhibitors

Mustafi, S., Camarena, V., Volmar, C.-H., Huff, T. C., Sant, D. W., Brothers, S. P., Liu, Z.-J., Wahlestedt, C., & Wang, G. (2018) · Cancer Research

Protein Degradation and InhibitorsEpigenetics and DNA Methylation

Cited by 47