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Personalized medicine in psychiatry: problems and promises

Ozomaro, Uzoezi, Wahlestedt, Claes, Nemeroff, Charles B·2013·BMC Medicine
DOI 10.1186/1741-7015-11-132PMC PMC3668172
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Abstract

The central theme of personalized medicine is the premise that an individual’s unique physiologic characteristics play a significant role in both disease vulnerability and in response to specific therapies. The major goals of personalized medicine are therefore to predict an individual’s susceptibility to developing an illness, achieve accurate diagnosis, and optimize the most efficient and favorable response to treatment. The goal of achieving personalized medicine in psychiatry is a laudable one, because its attainment should be associated with a marked reduction in morbidity and mortality. In this review, we summarize an illustrative selection of studies that are laying the foundation towards personalizing medicine in major depressive disorder, bipolar disorder, and schizophrenia. In addition, we present emerging applications that are likely to advance personalized medicine in psychiatry, with an emphasis on novel biomarkers and neuroimaging.

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Authors
Ozomaro, U., Wahlestedt, C., & Nemeroff, C. B.
Venue
BMC Medicine
Publisher
Springer Science and Business Media LLC
Published
2013-05-16
Volume
11
Issue
1
ISSN
1741-7015
DOI
10.1186/1741-7015-11-132
PMC
PMC3668172
Cited by
237
References
38
Language
en
Licence
www.springer.com/tdm (unspecified)

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