Kipp, Markus

The cuprizone animal model: new insights into an old story

Kipp, M., Clarner, T., Dang, J., Copray, S., & Beyer, C. (2009) · Acta Neuropathologica

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 481

Oligodendrocyte‐microglia cross‐talk in the central nervous system

Peferoen, L., Kipp, M., van der Valk, P., van Noort, J. M., & Amor, S. (2014) · Immunology

Neuroinflammation and Neurodegeneration MechanismsMultiple Sclerosis Research Studies

Cited by 438

Astrocytes regulate myelin clearance through recruitment of microglia during cuprizone-induced demyelination

Skripuletz, T., Hackstette, D., Bauer, K., Gudi, V., Pul, R., Voss, E., Berger, K., Kipp, M., Baumgärtner, W., & Stangel, M. (2013) · Brain

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 376

Multiple sclerosis animal models: a clinical and histopathological perspective

Kipp, M., Nyamoya, S., Hochstrasser, T., & Amor, S. (2017) · Brain Pathology

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 226

The Cuprizone Model: Dos and Do Nots

Zhan, J., Mann, T., Joost, S., Behrangi, N., Frank, M., & Kipp, M. (2020) · Cells

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 171

Myelin debris regulates inflammatory responses in an experimental demyelination animal model and multiple sclerosis lesions

Clarner, T., Diederichs, F., Berger, K., Denecke, B., Gan, L., van der Valk, P., Beyer, C., Amor, S., & Kipp, M. (2012) · Glia

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 155

CXCL10 Triggers Early Microglial Activation in the Cuprizone Model

Clarner, T., Janssen, K., Nellessen, L., Stangel, M., Skripuletz, T., Krauspe, B., Hess, F.-M., Denecke, B., Beutner, C., Linnartz-Gerlach, B., et al. (2015) · The Journal of Immunology

Neuroinflammation and Neurodegeneration MechanismsMultiple Sclerosis Research Studies

Cited by 150

Inflammatory Response and Chemokine Expression in the White Matter Corpus Callosum and Gray Matter Cortex Region During Cuprizone-Induced Demyelination

Buschmann, J. P., Berger, K., Awad, H., Clarner, T., Beyer, C., & Kipp, M. (2012) · Journal of Molecular Neuroscience

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 133

Cuprizone treatment induces demyelination and astrocytosis in the mouse hippocampus

Norkute, A., Hieble, A., Braun, A., Johann, S., Clarner, T., Baumgartner, W., Beyer, C., & Kipp, M. (2009) · Journal of Neuroscience Research

Multiple Sclerosis Research StudiesNeurological Disease Mechanisms and Treatments

Cited by 123

Cuprizone Treatment Induces Distinct Demyelination, Astrocytosis, and Microglia Cell Invasion or Proliferation in the Mouse Cerebellum

Groebe, A., Clarner, T., Baumgartner, W., Dang, J., Beyer, C., & Kipp, M. (2009) · The Cerebellum

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 116

Anatomical Distribution of Cuprizone-Induced Lesions in C57BL6 Mice

Goldberg, J., Clarner, T., Beyer, C., & Kipp, M. (2015) · Journal of Molecular Neuroscience

Multiple Sclerosis Research StudiesNeurological Disease Mechanisms and Treatments

Cited by 96

Activation of the astrocytic Nrf2/ARE system ameliorates the formation of demyelinating lesions in a multiple sclerosis animal model: Astrocytic Nrf2 Hyperactivation Prevents the Formation of Demyelinating Lesions

Draheim, T., Liessem, A., Scheld, M., Wilms, F., Weißflog, M., Denecke, B., Kensler, T. W., Zendedel, A., Beyer, C., Kipp, M., et al. (2016) · Glia

Multiple Sclerosis Research StudiesGenomics, phytochemicals, and oxidative stress

Cited by 95

The sphingosine 1‐phosphate receptor agonist FTY 720 is neuroprotective after cuprizone‐induced CNS demyelination

Slowik, A., Schmidt, T., Beyer, C., Amor, S., Clarner, T., & Kipp, M. (2015) · British Journal of Pharmacology

Multiple Sclerosis Research StudiesSphingolipid Metabolism and Signaling

Cited by 94

Synaptophysin Is a Reliable Marker for Axonal Damage

Gudi, V., Gai, L., Herder, V., Tejedor, L. S., Kipp, M., Amor, S., Sühs, K.-W., Hansmann, F., Beineke, A., Baumgärtner, W., et al. (2017) · Journal of Neuropathology & Experimental Neurology

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 87

Cuprizone effect on myelination, astrogliosis and microglia attraction in the mouse basal ganglia

Pott, F., Gingele, S., Clarner, T., Dang, J., Baumgartner, W., Beyer, C., & Kipp, M. (2009) · Brain Research

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 85

BLBP-expression in astrocytes during experimental demyelination and in human multiple sclerosis lesions

Kipp, M., Gingele, S., Pott, F., Clarner, T., van der Valk, P., Denecke, B., Gan, L., Siffrin, V., Zipp, F., Dreher, W., et al. (2011) · Brain, Behavior, and Immunity

Multiple Sclerosis Research StudiesNeurogenesis and neuroplasticity mechanisms

Cited by 83

Oestrogen and Progesterone Reduce Lipopolysaccharide‐Induced Expression of Tumour Necrosis Factor‐α and Interleukin‐18 in Midbrain Astrocytes

Kipp, M., Karakaya, S., Johann, S., Kampmann, E., Mey, J., & Beyer, C. (2007) · Journal of Neuroendocrinology

Neuroinflammation and Neurodegeneration MechanismsEstrogen and related hormone effects

Cited by 83

Neurodegeneration Triggers Peripheral Immune Cell Recruitment into the Forebrain

Scheld, M., Rüther, B. J., Große-Veldmann, R., Ohl, K., Tenbrock, K., Dreymüller, D., Fallier-Becker, P., Zendedel, A., Beyer, C., Clarner, T., et al. (2016) · The Journal of Neuroscience

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 82

Motor Behavioral Deficits in the Cuprizone Model: Validity of the Rotarod Test Paradigm

Lubrich, C., Giesler, P., & Kipp, M. (2022) · International Journal of Molecular Sciences

Multiple Sclerosis Research StudiesMotor Control and Adaptation

Cited by 77

Combination of cuprizone and experimental autoimmune encephalomyelitis to study inflammatory brain lesion formation and progression

Rüther, B. J., Scheld, M., Dreymueller, D., Clarner, T., Kress, E., Brandenburg, L., Swartenbroekx, T., Hoornaert, C., Ponsaerts, P., Fallier‐Becker, P., et al. (2017) · Glia

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 76

Different Methods for Evaluating Microglial Activation Using Anti-Ionized Calcium-Binding Adaptor Protein-1 Immunohistochemistry in the Cuprizone Model

Wittekindt, M., Kaddatz, H., Joost, S., Staffeld, A., Bitar, Y., Kipp, M., & Frintrop, L. (2022) · Cells

Neuroinflammation and Neurodegeneration MechanismsMultiple Sclerosis Research Studies

Cited by 74

Short-Term Cuprizone Feeding Induces Selective Amino Acid Deprivation with Concomitant Activation of an Integrated Stress Response in Oligodendrocytes

Goldberg, J., Daniel, M., van Heuvel, Y., Victor, M., Beyer, C., Clarner, T., & Kipp, M. (2013) · Cellular and Molecular Neurobiology

Endoplasmic Reticulum Stress and DiseaseMultiple Sclerosis Research Studies

Cited by 62

Ectopic lymphoid follicles in progressive multiple sclerosis: From patients to animal models

Zhan, J., Kipp, M., Han, W., & Kaddatz, H. (2021) · Immunology

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 49

Regional heterogeneity of cuprizone-induced demyelination: Topographical aspects of the midline of the corpus callosum

Schmidt, T., Awad, H., Slowik, A., Beyer, C., Kipp, M., & Clarner, T. (2013) · Journal of Molecular Neuroscience

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 49