Poutanen, Matti

The gut microbiota is a major regulator of androgen metabolism in intestinal contents

Colldén, H., Landin, A., Wallenius, V., Elebring, E., Fändriks, L., Nilsson, M. E., Ryberg, H., Poutanen, M., Sjögren, K., Vandenput, L., et al. (2019) · American Journal of Physiology-Endocrinology and Metabolism

Gut microbiota and healthHormonal and reproductive studies

Cited by 257

Endometrial and endometriotic concentrations of estrone and estradiol are determined by local metabolism rather than circulating levels

Huhtinen, K., Desai, R., Ståhle, M., Salminen, A., Handelsman, D. J., Perheentupa, A., & Poutanen, M. (2012) · The Journal of Clinical Endocrinology & Metabolism

Endometriosis Research and TreatmentEstrogen and related hormone effects

Cited by 195

Human 17 β-hydroxysteroid dehydrogenase type 1 and type 2 isoenzymes have opposite activities in cultured cells and characteristic cell- and tissue-specific expression

MIETTINEN, M. M., MUSTONEN, M. V. J., POUTANEN, M. H., ISOMAA, V. V., & VIHKO, R. K. (1996) · Biochemical Journal

Estrogen and related hormone effectsSteroid Chemistry and Biochemistry

Cited by 188

Aromatase and 17 beta-hydroxysteroid dehydrogenase type 1 in human breast carcinoma.

Sasano, H., Frost, A. R., Saitoh, R., Harada, N., Poutanen, M., Vihko, R., Bulun, S. E., Silverberg, S. G., & Nagura, H. (1996) · The Journal of Clinical Endocrinology & Metabolism

Estrogen and related hormone effectsBreast Cancer Treatment Studies

Cited by 167

The androgen and progesterone receptors regulate distinct gene networks and cellular functions in decidualizing endometrium

Cloke, B., Huhtinen, K., Fusi, L., Kajihara, T., Yliheikkilä, M., Ho, K.-K., Teklenburg, G., Lavery, S., Jones, M. C., Trew, G., et al. (2008) · Endocrinology

Reproductive System and PregnancyEstrogen and related hormone effects

Cited by 159

Peroxisomal multifunctional enzyme of β-oxidation metabolizing d-3-hydroxyacyl-CoA esters in rat liver: molecular cloning, expression and characterization

QIN, Y.-M., POUTANEN, M. H., HELANDER, H. M., KVIST, A.-P., SIIVARI, K. M., SCHMITZ, W., CONZELMANN, E., HELLMAN, U., & HILTUNEN, J. K. (1997) · Biochemical Journal

Metabolism and Genetic DisordersPeroxisome Proliferator-Activated Receptors

Cited by 107

Estrogen biosynthesis and signaling in endometriosis

Huhtinen, K., Ståhle, M., Perheentupa, A., & Poutanen, M. (2012) · Molecular and Cellular Endocrinology

Endometriosis Research and TreatmentEstrogen and related hormone effects

Cited by 107

Human 17β-Hydroxysteroid Dehydrogenase Type 2 Messenger Ribonucleic Acid Expression and Localization in Term Placenta and in Endometrium during the Menstrual Cycle1

Mustonen, M. V. J., Isomaa, V. V., Vaskivuo, T., Tapanainen, J., Poutanen, M. H., Stenbäck, F., Vihko, R. K., & Vihko, P. T. (1998) · The Journal of Clinical Endocrinology & Metabolism

Estrogen and related hormone effectsReproductive System and Pregnancy

Cited by 84

Intra-tissue steroid profiling indicates differential progesterone and testosterone metabolism in the endometrium and endometriosis lesions

Huhtinen, K., Saloniemi-Heinonen, T., Keski-Rahkonen, P., Desai, R., Laajala, D., Ståhle, M., Häkkinen, M. R., Awosanya, M., Suvitie, P., Kujari, H., et al. (2014) · The Journal of Clinical Endocrinology & Metabolism

Endometriosis Research and TreatmentEstrogen and related hormone effects

Cited by 75

Simultaneous analysis by LC–MS/MS of 22 ketosteroids with hydroxylamine derivatization and underivatized estradiol from human plasma, serum and prostate tissue

Häkkinen, M. R., Murtola, T., Voutilainen, R., Poutanen, M., Linnanen, T., Koskivuori, J., Lakka, T., Jääskeläinen, J., & Auriola, S. (2019) · Journal of Pharmaceutical and Biomedical Analysis

Analytical Methods in PharmaceuticalsAnalytical Chemistry and Chromatography

Cited by 74

Increased adipose tissue aromatase activity improves insulin sensitivity and reduces adipose tissue inflammation in male mice

Ohlsson, C., Hammarstedt, A., Vandenput, L., Saarinen, N., Ryberg, H., Windahl, S. H., Farman, H. H., Jansson, J.-O., Movérare-Skrtic, S., Smith, U., et al. (2017) · American Journal of Physiology-Endocrinology and Metabolism

Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and Metabolism

Cited by 55

Optimized design and analysis of preclinical intervention studies in vivo

Laajala, T. D., Jumppanen, M., Huhtaniemi, R., Fey, V., Kaur, A., Knuuttila, M., Aho, E., Oksala, R., Westermarck, J., Mäkelä, S., et al. (2016) · Scientific Reports

Statistical Methods in Clinical TrialsAnimal testing and alternatives

Cited by 48

LC-MS analysis of estradiol in human serum and endometrial tissue: Comparison of electrospray ionization, atmospheric pressure chemical ionization and atmospheric pressure photoionization

Keski‐Rahkonen, P., Huhtinen, K., Desai, R., Tim Harwood, D., Handelsman, D. J., Poutanen, M., & Auriola, S. (2013) · Journal of Mass Spectrometry

Mass Spectrometry Techniques and ApplicationsMetabolomics and Mass Spectrometry Studies

Cited by 47

Weight gain and inflammation regulate aromatase expression in male adipose tissue, as evidenced by reporter gene activity

Polari, L., Yatkin, E., Martínez Chacón, M. G., Ahotupa, M., Smeds, A., Strauss, L., Zhang, F., Poutanen, M., Saarinen, N., & Mäkelä, S. I. (2015) · Molecular and Cellular Endocrinology

Adipokines, Inflammation, and Metabolic DiseasesEstrogen and related hormone effects

Cited by 38

Dicer ablation in Kiss1 neurons impairs puberty and fertility preferentially in female mice

Roa, J., Ruiz-Cruz, M., Ruiz-Pino, F., Onieva, R., Vazquez, M. J., Sanchez-Tapia, M. J., Ruiz-Rodriguez, J. M., Sobrino, V., Barroso, A., Heras, V., et al. (2022) · Nature Communications

Hypothalamic control of reproductive hormonesReproductive Biology and Fertility

Cited by 22

Sex Steroid-Dependent and -Independent Action of Hydroxysteroid (17β) Dehydrogenase 2: Evidence from Transgenic Female Mice

Shen, Z., Saloniemi, T., Rönnblad, A., Järvensivu, P., Pakarinen, P., & Poutanen, M. (2009) · Endocrinology

Sexual Differentiation and DisordersEstrogen and related hormone effects

Cited by 10