Sicheri, Frank

Persistence of serum and saliva antibody responses to SARS-CoV-2 spike antigens in COVID-19 patients

Isho, B., Abe, K. T., Zuo, M., Jamal, A. J., Rathod, B., Wang, J. H., Li, Z., Chao, G., Rojas, O. L., Bang, Y. M., et al. (2020) · Science Immunology

SARS-CoV-2 and COVID-19 ResearchSARS-CoV-2 detection and testing

Cited by 822

53BP1 is a reader of the DNA-damage-induced H2A Lys 15 ubiquitin mark

Fradet-Turcotte, A., Canny, M. D., Escribano-Díaz, C., Orthwein, A., Leung, C. C. Y., Huang, H., Landry, M.-C., Kitevski-LeBlanc, J., Noordermeer, S. M., Sicheri, F., et al. (2013) · Nature

DNA Repair MechanismsGenomics and Chromatin Dynamics

Cited by 686

A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein

Goudreault, M., D'Ambrosio, L. M., Kean, M. J., Mullin, M. J., Larsen, B. G., Sanchez, A., Chaudhry, S., Chen, G. I., Sicheri, F., Nesvizhskii, A. I., et al. (2009) · Molecular & Cellular Proteomics

Protein Kinase Regulation and GTPase SignalingVascular Malformations Diagnosis and Treatment

Cited by 359

Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB1

Nakada, S., Tai, I., Panier, S., Al-Hakim, A., Iemura, S.-I., Juang, Y.-C., O’Donnell, L., Kumakubo, A., Munro, M., Sicheri, F., et al. (2010) · Nature

Ubiquitin and proteasome pathwaysDNA Repair Mechanisms

Cited by 357

Metformin reduces liver glucose production by inhibition of fructose-1-6-bisphosphatase

Hunter, R. W., Hughey, C. C., Lantier, L., Sundelin, E. I., Peggie, M., Zeqiraj, E., Sicheri, F., Jessen, N., Wasserman, D. H., & Sakamoto, K. (2018) · Nature Medicine

Metabolism, Diabetes, and CancerDiabetes Treatment and Management

Cited by 313

Inhibition of RAS function through targeting an allosteric regulatory site

Spencer-Smith, R., Koide, A., Zhou, Y., Eguchi, R. R., Sha, F., Gajwani, P., Santana, D., Gupta, A., Jacobs, M., Herrero-Garcia, E., et al. (2017) · Nature Chemical Biology

Protein Kinase Regulation and GTPase SignalingMelanoma and MAPK Pathways

Cited by 283

Suprafacial Orientation of the SCFCdc4 Dimer Accommodates Multiple Geometries for Substrate Ubiquitination

Tang, X., Orlicky, S., Lin, Z., Willems, A., Neculai, D., Ceccarelli, D., Mercurio, F., Shilton, B. H., Sicheri, F., & Tyers, M. (2007) · Cell

Ubiquitin and proteasome pathwaysProtein Degradation and Inhibitors

Cited by 209

A feed forward loop enforces YAP/TAZ signaling during tumorigenesis

Gill, M. K., Christova, T., Zhang, Y. Y., Gregorieff, A., Zhang, L., Narimatsu, M., Song, S., Xiong, S., Couzens, A. L., Tong, J., et al. (2018) · Nature Communications

Hippo pathway signaling and YAP/TAZCancer-related molecular mechanisms research

Cited by 95

Structural basis for the recruitment of glycogen synthase by glycogenin

Zeqiraj, E., Tang, X., Hunter, R. W., García-Rocha, M., Judd, A., Deak, M., von Wilamowitz-Moellendorff, A., Kurinov, I., Guinovart, J. J., Tyers, M., et al. (2014) · Proceedings of the National Academy of Sciences

Glycogen Storage Diseases and MyoclonusMetabolism, Diabetes, and Cancer

Cited by 57

Getting a handle on glycogen synthase – Its interaction with glycogenin

Zeqiraj, E., & Sicheri, F. (2015) · Molecular Aspects of Medicine

Glycogen Storage Diseases and MyoclonusMetabolism, Diabetes, and Cancer

Cited by 42