Flavell, Richard A.

IL-13Rα2 and IL-10 coordinately suppress airway inflammation, airway-hyperreactivity, and fibrosis in mice

Wilson, M. S., Elnekave, E., Mentink-Kane, M. M., Hodges, M. G., Pesce, J. T., Ramalingam, T. R., Thompson, R. W., Kamanaka, M., Flavell, R. A., Keane-Myers, A., et al. (2007) · Journal of Clinical Investigation

Asthma and respiratory diseasesIL-33, ST2, and ILC Pathways

Cited by 137

Targeted Expression of Calcitonin Gene-Related Peptide to Osteoblasts Increases Bone Density in Mice

Ballica, R., Valentijn, K., Khachatryan, A., Guerder, S., Kapadia, S., Gundberg, C., Gilligan, J., Flavell, R. A., & Vignery, A. (1999) · Journal of Bone and Mineral Research

Bone Metabolism and DiseasesBone health and osteoporosis research

Cited by 133

CD40 signaling regulates innate and adaptive activation of microglia in response to amyloid β‐peptide

Townsend, K. P., Town, T., Mori, T., Lue, L., Shytle, D., Sanberg, P. R., Morgan, D., Fernandez, F., Flavell, R. A., & Tan, J. (2005) · European Journal of Immunology

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 121

Intestinal B cells license metabolic T-cell activation in NASH microbiota/antigen-independently and contribute to fibrosis by IgA-FcR signalling

Kotsiliti, E., Leone, V., Schuehle, S., Govaere, O., Li, H., Wolf, M. J., Horvatic, H., Bierwirth, S., Hundertmark, J., Inverso, D., et al. (2023) · Journal of Hepatology

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 108

Inflammasome components Asc and caspase-1 mediate biomaterial-induced inflammation and foreign body response

Malik, A. F., Hoque, R., Ouyang, X., Ghani, A., Hong, E., Khan, K., Moore, L. B., Ng, G., Munro, F., Flavell, R. A., et al. (2011) · Proceedings of the National Academy of Sciences

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 107

Humanized mouse liver reveals endothelial control of essential hepatic metabolic functions

Kaffe, E., Roulis, M., Zhao, J., Qu, R., Sefik, E., Mirza, H., Zhou, J., Zheng, Y., Charkoftaki, G., Vasiliou, V., et al. (2023) · Cell

Liver physiology and pathologyLiver Disease Diagnosis and Treatment

Cited by 99

The stumpy gene is required for mammalian ciliogenesis

Town, T., Breunig, J. J., Sarkisian, M. R., Spilianakis, C., Ayoub, A. E., Liu, X., Ferrandino, A. F., Gallagher, A. R., Li, M. O., Rakic, P., et al. (2008) · Proceedings of the National Academy of Sciences

Genetic and Kidney Cyst DiseasesCystic Fibrosis Research Advances

Cited by 91

Selective degradation of PU.1 during autophagy represses the differentiation and antitumour activity of TH9 cells

Rivera Vargas, T., Cai, Z., Shen, Y., Dosset, M., Benoit-Lizon, I., Martin, T., Roussey, A., Flavell, R. A., Ghiringhelli, F., & Apetoh, L. (2017) · Nature Communications

T-cell and B-cell ImmunologyAutophagy in Disease and Therapy

Cited by 87

IL9 leads to airway inflammation by inducing IL13 expression in airway epithelial cells

Temann, U.-A., Laouar, Y., Eynon, E. E., Homer, R., & Flavell, R. A. (2006) · International Immunology

Asthma and respiratory diseasesIL-33, ST2, and ILC Pathways

Cited by 86

CD4 T cell-intrinsic STING signaling controls the differentiation and effector functions of T H 1 and T H 9 cells

Benoit-Lizon, I., Jacquin, E., Rivera Vargas, T., Richard, C., Roussey, A., Dal Zuffo, L., Martin, T., Melis, A., Vinokurova, D., Shahoei, S. H., et al. (2022) · Journal for ImmunoTherapy of Cancer

interferon and immune responsesImmunotherapy and Immune Responses

Cited by 85

Plexin-B1 plays a redundant role during mouse development and in tumour angiogenesis

Fazzari, P., Penachioni, J., Gianola, S., Rossi, F., Eickholt, B. J., Maina, F., Alexopoulou, L., Sottile, A., Comoglio, P. M., Flavell, R. A., et al. (2007) · BMC Developmental Biology

Axon Guidance and Neuronal SignalingAngiogenesis and VEGF in Cancer

Cited by 85

Shaping of Intestinal Microbiota in Nlrp6- and Rag2-Deficient Mice Depends on Community Structure

Gálvez, E. J. C., Iljazovic, A., Gronow, A., Flavell, R., & Strowig, T. (2017) · Cell Reports

Gut microbiota and healthImmune Response and Inflammation

Cited by 81

IRF8‐dependent Molecular Complexes Control the Th9 Transcriptional Program

Humblin, E., Thibaudin, M., Chalmin, F., Derangère, V., Limagne, E., Richard, C., Flavell, R. A., Chevrier, S., Ladoire, S., Berger, H., et al. (2017) · Nature Communications

T-cell and B-cell ImmunologyPsoriasis: Treatment and Pathogenesis

Cited by 67

Evidence for a pathogenic role of extrafollicular, IL-10–producing CCR6 + B helper T cells in systemic lupus erythematosus

Facciotti, F., Larghi, P., Bosotti, R., Vasco, C., Gagliani, N., Cordiglieri, C., Mazzara, S., Ranzani, V., Rottoli, E., Curti, S., et al. (2020) · Proceedings of the National Academy of Sciences

Systemic Lupus Erythematosus ResearchT-cell and B-cell Immunology

Cited by 63

Antigen-mediated regulation in monoclonal gammopathies and myeloma

Nair, S., Sng, J., Boddupalli, C. S., Seckinger, A., Chesi, M., Fulciniti, M., Zhang, L., Rauniyar, N., Lopez, M., Neparidze, N., et al. (2018) · JCI Insight

Multiple Myeloma Research and TreatmentsChronic Lymphocytic Leukemia Research

Cited by 60

IL-10–producing forkhead box protein 3–negative regulatory T cells inhibit B-cell responses and are involved in systemic lupus erythematosus

Facciotti, F., Gagliani, N., Häringer, B., Alfen, J. S., Penatti, A., Maglie, S., Paroni, M., Iseppon, A., Moro, M., Crosti, M. C., et al. (2016) · Journal of Allergy and Clinical Immunology

T-cell and B-cell ImmunologySystemic Lupus Erythematosus Research

Cited by 43

Requirement of JIP scaffold proteins for NMDA-mediated signal transduction

Kennedy, N. J., Martin, G., Ehrhardt, A. G., Cavanagh-Kyros, J., Kuan, C.-Y., Rakic, P., Flavell, R. A., Treistman, S. N., & Davis, R. J. (2007) · Genes & Development

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 40

Requirement of JIP1-mediated c-Jun N-terminal kinase activation for obesity-induced insulin resistance

Morel, C., Standen, C. L., Jung, D. Y., Gray, S., Ong, H., Flavell, R. A., Kim, J. K., & Davis, R. J. (2010) · Molecular and Cellular Biology

Adipokines, Inflammation, and Metabolic DiseasesMetabolism, Diabetes, and Cancer

Cited by 30

NLRP6 and Dysbiosis: Avoiding the Luring Attraction of Over-Simplification

Elinav, E., Henao-Mejia, J., Strowig, T., & Flavell, R. (2018) · Immunity

Gut microbiota and healthInflammasome and immune disorders

Cited by 24