Flavell, Richard A.

Pancreatic Lymph Node-Derived CD4+CD25+ Treg Cells

Green, E. A., Choi, Y., & Flavell, R. A. (2002) · Immunity

T-cell and B-cell ImmunologyDiabetes and associated disorders

Cited by 310

Nlrp6 regulates intestinal antiviral innate immunity

Wang, P., Zhu, S., Yang, L., Cui, S., Pan, W., Jackson, R., Zheng, Y., Rongvaux, A., Sun, Q., Yang, G., et al. (2015) · Science

interferon and immune responsesInflammasome and immune disorders

Cited by 304

JNK potentiates TNF-stimulated necrosis by increasing the production of cytotoxic reactive oxygen species

Ventura, J.-J., Cogswell, P., Flavell, R. A., Baldwin, A. S., & Davis, R. J. (2004) · Genes & Development

Cell death mechanisms and regulationNF-κB Signaling Pathways

Cited by 303

Inflammasome-activating nanoparticles as modular systems for optimizing vaccine efficacy

Demento, S. L., Eisenbarth, S. C., Foellmer, H. G., Platt, C., Caplan, M. J., Mark Saltzman, W., Mellman, I., Ledizet, M., Fikrig, E., Flavell, R. A., et al. (2009) · Vaccine

Immunotherapy and Immune ResponsesInflammasome and immune disorders

Cited by 290

Carbon monoxide inhibition of apoptosis during ischemia-reperfusion lung injury is dependent on the p38 mitogen-activated protein kinase pathway and involves caspase 3

Zhang, X., Shan, P., Otterbein, L. E., Alam, J., Flavell, R. A., Davis, R. J., Choi, A. M. K., & Lee, P. J. (2003) · Journal of Biological Chemistry

Heme Oxygenase-1 and Carbon MonoxideCell death mechanisms and regulation

Cited by 288

β-Globin gene inactivation by DNA translocation in γβ-thalassaemi

Kioussis, D., Vanin, E., deLange, T., Flavell, R. A., & Grosveld, F. G. (1983) · Nature

Hemoglobinopathies and Related DisordersGenomics and Chromatin Dynamics

Cited by 264

Apoptotic hepatocyte DNA inhibits hepatic stellate cell chemotaxis via toll-like receptor 9

Watanabe, A., Hashmi, A., Gomes, D. A., Town, T., Badou, A., Flavell, R. A., & Mehal, W. Z. (2007) · Hepatology

Liver physiology and pathologyImmune Response and Inflammation

Cited by 262

Autocrine/paracrine TGFβ1 is required for the development of epidermal Langerhans cells

Kaplan, D. H., Li, M. O., Jenison, M. C., Shlomchik, W. D., Flavell, R. A., & Shlomchik, M. J. (2007) · The Journal of Experimental Medicine

TGF-β signaling in diseasesT-cell and B-cell Immunology

Cited by 254

The translation of non-canonical open reading frames controls mucosal immunity

Jackson, R., Kroehling, L., Khitun, A., Bailis, W., Jarret, A., York, A. G., Khan, O. M., Brewer, J. R., Skadow, M. H., Duizer, C., et al. (2018) · Nature

RNA and protein synthesis mechanismsRNA Research and Splicing

Cited by 242

Requirement of the JIP1 scaffold protein for stress-induced JNK activation

Whitmarsh, A. J., Kuan, C.-Y., Kennedy, N. J., Kelkar, N., Haydar, T. F., Mordes, J. P., Appel, M., Rossini, A. A., Jones, S. N., Flavell, R. A., et al. (2001) · Genes & Development

Protein Kinase Regulation and GTPase SignalingNF-κB Signaling Pathways

Cited by 238

Bacterial Flagellin Stimulates Toll‐Like Receptor 5–Dependent Defense against Vancomycin‐Resistant Enterococcus Infection

Kinnebrew, M. A., Ubeda, C., Zenewicz, L. A., Smith, N., Flavell, R. A., & Pamer, E. G. (2010) · The Journal of Infectious Diseases

Immune Response and InflammationAntimicrobial Peptides and Activities

Cited by 236

RNA m6A modification and its function in diseases

Tong, J., Flavell, R. A., & Li, H.-B. (2018) · Frontiers of Medicine

RNA modifications and cancerRNA regulation and disease

Cited by 233

Inflammasome-mediated regulation of hepatic stellate cells

Watanabe, A., Sohail, M. A., Gomes, D. A., Hashmi, A., Nagata, J., Sutterwala, F. S., Mahmood, S., Jhandier, M. N., Shi, Y., Flavell, R. A., et al. (2009) · American Journal of Physiology-Gastrointestinal and Liver Physiology

Liver physiology and pathologyInflammasome and immune disorders

Cited by 233

Multisite Phosphorylation Regulates Bim Stability and Apoptotic Activity

Hübner, A., Barrett, T., Flavell, R. A., & Davis, R. J. (2008) · Molecular Cell

Cell death mechanisms and regulationCancer-related Molecular Pathways

Cited by 228

Microbiota-driven interleukin-17-producing cells and eosinophils synergize to accelerate multiple myeloma progression

Calcinotto, A., Brevi, A., Chesi, M., Ferrarese, R., Garcia Perez, L., Grioni, M., Kumar, S., Garbitt, V. M., Sharik, M. E., Henderson, K. J., et al. (2018) · Nature Communications

Multiple Myeloma Research and TreatmentsGut microbiota and health

Cited by 223

Role of CD40 ligand in amyloidosis in transgenic Alzheimer's mice

Tan, J., Town, T., Crawford, F., Mori, T., DelleDonne, A., Crescentini, R., Obregon, D., Flavell, R. A., & Mullan, M. J. (2002) · Nature Neuroscience

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 217

Targeted expression of IL-11 in the murine airway causes lymphocytic inflammation, bronchial remodeling, and airways obstruction.

Tang, W., Geba, G. P., Zheng, T., Ray, P., Homer, R. J., Kuhn, C., Flavell, R. A., & Elias, J. A. (1996) · Journal of Clinical Investigation

Asthma and respiratory diseasesChronic Obstructive Pulmonary Disease (COPD) Research

Cited by 210

Pulmonary overexpression of IL-9 induces Th2 cytokine expression, leading to immune pathology

Temann, U.-A., Ray, P., & Flavell, R. A. (2002) · Journal of Clinical Investigation

Asthma and respiratory diseasesIL-33, ST2, and ILC Pathways

Cited by 201

The Stromal Intervention: Regulation of Immunity and Inflammation at the Epithelial-Mesenchymal Barrier

Nowarski, R., Jackson, R., & Flavell, R. A. (2017) · Cell

IL-33, ST2, and ILC PathwaysT-cell and B-cell Immunology

Cited by 191

T-Cells in Alzheimer's Disease

Town, T., Tan, J., Flavell, R. A., & Mullan, M. (2005) · NeuroMolecular Medicine

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 183

IL-22 promotes fibroblast-mediated wound repair in the skin

McGee, H. M., Schmidt, B. A., Booth, C. J., Yancopoulos, G. D., Valenzuela, D. M., Murphy, A. J., Stevens, S., Flavell, R. A., & Horsley, V. (2013) · Journal of Investigative Dermatology

Wound Healing and TreatmentsCytokine Signaling Pathways and Interactions

Cited by 161

Detection of differentially abundant cell subpopulations in scRNA-seq data

Zhao, J., Jaffe, A., Li, H., Lindenbaum, O., Sefik, E., Jackson, R., Cheng, X., Flavell, R. A., & Kluger, Y. (2021) · Proceedings of the National Academy of Sciences

Single-cell and spatial transcriptomicsGene expression and cancer classification

Cited by 154

The Hematopoiesis-Specific GTP-Binding Protein RhoH Is GTPase Deficient and Modulates Activities of Other Rho GTPases by an Inhibitory Function

Li, X., Bu, X., Lu, B., Avraham, H., Flavell, R. A., & Lim, B. (2002) · Molecular and Cellular Biology

Protein Kinase Regulation and GTPase SignalingCellular transport and secretion

Cited by 153

Role of STAT3 in liver regeneration: survival, DNA synthesis, inflammatory reaction and liver mass recovery

Moh, A., Iwamoto, Y., Chai, G.-X., Zhang, S. S.-M., Kano, A., Yang, D. D., Zhang, W., Wang, J., Jacoby, J. J., Gao, B., et al. (2007) · Laboratory Investigation

Liver physiology and pathologyCytokine Signaling Pathways and Interactions

Cited by 147