Aikawa, Masanori

Macrophage-Derived Matrix Vesicles: An Alternative Novel Mechanism for Microcalcification in Atherosclerotic Plaques

New, S. E. P., Goettsch, C., Aikawa, M., Marchini, J. F., Shibasaki, M., Yabusaki, K., Libby, P., Shanahan, C. M., Croce, K., & Aikawa, E. (2013) · Circulation Research

Parathyroid Disorders and TreatmentsExtracellular vesicles in disease

Cited by 451

Genesis and growth of extracellular-vesicle-derived microcalcification in atherosclerotic plaques

Hutcheson, J. D., Goettsch, C., Bertazzo, S., Maldonado, N., Ruiz, J. L., Goh, W., Yabusaki, K., Faits, T., Bouten, C., Franck, G., et al. (2016) · Nature Materials

Calcium Carbonate Crystallization and InhibitionDermatological and Skeletal Disorders

Cited by 419

Apolipoprotein CIII Induces Expression of Vascular Cell Adhesion Molecule-1 in Vascular Endothelial Cells and Increases Adhesion of Monocytic Cells

Kawakami, A., Aikawa, M., Alcaide, P., Luscinskas, F. W., Libby, P., & Sacks, F. M. (2006) · Circulation

Atherosclerosis and Cardiovascular DiseasesCell Adhesion Molecules Research

Cited by 305

Spatiotemporal Multi-Omics Mapping Generates a Molecular Atlas of the Aortic Valve and Reveals Networks Driving Disease

Schlotter, F., Halu, A., Goto, S., Blaser, M. C., Body, S. C., Lee, L. H., Higashi, H., DeLaughter, D. M., Hutcheson, J. D., Vyas, P., et al. (2018) · Circulation

Cardiac Valve Diseases and TreatmentsAdvanced Proteomics Techniques and Applications

Cited by 256

Apolipoprotein CIII in Apolipoprotein B Lipoproteins Enhances the Adhesion of Human Monocytic Cells to Endothelial Cells

Kawakami, A., Aikawa, M., Libby, P., Alcaide, P., Luscinskas, F. W., & Sacks, F. M. (2006) · Circulation

Atherosclerosis and Cardiovascular DiseasesCholesterol and Lipid Metabolism

Cited by 206

High-Resolution Magnetic Resonance Imaging Enhanced With Superparamagnetic Nanoparticles Measures Macrophage Burden in Atherosclerosis

Morishige, K., Kacher, D. F., Libby, P., Josephson, L., Ganz, P., Weissleder, R., & Aikawa, M. (2010) · Circulation

Atherosclerosis and Cardiovascular DiseasesCardiac Imaging and Diagnostics

Cited by 168

The selective peroxisome proliferator-activated receptor alpha modulator (SPPARMα) paradigm: conceptual framework and therapeutic potential: A consensus statement from the International Atherosclerosis Society (IAS) and the Residual Risk Reduction Initiative (R3i) Foundation

Fruchart, J.-C., Santos, R. D., Aguilar-Salinas, C., Aikawa, M., Al Rasadi, K., Amarenco, P., Barter, P. J., Ceska, R., Corsini, A., Després, J.-P., et al. (2019) · Cardiovascular Diabetology

Peroxisome Proliferator-Activated ReceptorsLipoproteins and Cardiovascular Health

Cited by 140

Multiomics of Tissue Extracellular Vesicles Identifies Unique Modulators of Atherosclerosis and Calcific Aortic Valve Stenosis

Blaser, M. C., Buffolo, F., Halu, A., Turner, M. E., Schlotter, F., Higashi, H., Pantano, L., Clift, C. L., Saddic, L. A., Atkins, S. K., et al. (2023) · Circulation

Extracellular vesicles in diseaseAtherosclerosis and Cardiovascular Diseases

Cited by 114

ApoC-III is a novel inducer of calcification in human aortic valves

Schlotter, F., de Freitas, R. C. C., Rogers, M. A., Blaser, M. C., Wu, P.-J., Higashi, H., Halu, A., Iqbal, F., Andraski, A. B., Rodia, C. N., et al. (2021) · Journal of Biological Chemistry

Cardiac Valve Diseases and TreatmentsAtherosclerosis and Cardiovascular Diseases

Cited by 49

Macrophage heterogeneity and efferocytosis: Beyond the M1/M2 dichotomy

Kumar Jha, P., Aikawa, M., & Aikawa, E. (2024) · Circulation Research

Phagocytosis and Immune RegulationImmune cells in cancer

Cited by 45

Nutrient supplementation mitigates retinal dysfunction in Acox1 knockout mice with impaired peroxisomal fatty acid oxidation.

Boeck, M., Yagi, H., Chen, C. T., Zeng, Y., Lee, D., Nian, S., Kasai, T., Lee, J., Hirst, V., Wang, C., et al. (2025) · Journal of Advanced Research

Retinal Development and DisordersMetabolism and Genetic Disorders

Cited by 4

A HIGHLY SELECTIVE PPARα AGONIST K-877 SUPPRESSES NEOINTIMA FORMATION FOLLOWING CORONARY STENTING IN SWINE

Iwata, H., Osborn, E., Ughi, G., Murakami, K., Goettsch, C., Hutcheson, J., Mauskapf, A., Mattson, P., Libby, P., Aikawa, E., et al. (2016) · Journal of the American College of Cardiology

Coronary Interventions and DiagnosticsPeroxisome Proliferator-Activated Receptors

Cited by 2