Palermo, Giulia

Allostery in Its Many Disguises: From Theory to Applications

Wodak, S. J., Paci, E., Dokholyan, N. V., Berezovsky, I. N., Horovitz, A., Li, J., Hilser, V. J., Bahar, I., Karanicolas, J., Stock, G., et al. (2019) · Structure

Protein Structure and DynamicsReceptor Mechanisms and Signaling

Cited by 404

Structural basis for Cas9 off-target activity

Pacesa, M., Lin, C.-H., Cléry, A., Saha, A., Arantes, P. R., Bargsten, K., Irby, M. J., Allain, F. H.-T., Palermo, G., Cameron, P., et al. (2022) · Cell

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 198

Key role of the REC lobe during CRISPR–Cas9 activation by ‘sensing’, ‘regulating’, and ‘locking’ the catalytic HNH domain

Palermo, G., Chen, J. S., Ricci, C. G., Rivalta, I., Jinek, M., Batista, V. S., Doudna, J. A., & McCammon, J. A. (2018) · Quarterly Reviews of Biophysics

CRISPR and Genetic EngineeringProtein Structure and Dynamics

Cited by 123

RNA targeting and cleavage by the type III-Dv CRISPR effector complex

Schwartz, E. A., Bravo, J. P. K., Ahsan, M., Macias, L. A., McCafferty, C. L., Dangerfield, T. L., Walker, J. N., Brodbelt, J. S., Palermo, G., Fineran, P. C., et al. (2024) · Nature Communications

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 30

CRISPR-Cas12a REC2–Nuc interactions drive target-strand cleavage and constrain trans cleavage

Newman, A., Saha, A., Starrs, L., Arantes, P. R., Palermo, G., & Burgio, G. (2025) · Nucleic Acids Research

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 14

CRISPR-Cas12a REC2 – NUC interactions drive target-strand cleavage and constrain trans cleavage

Newman, A., Saha, A., Starrs, L., Arantes, P. R., Palermo, G., & Burgio, G. (2025) · Nucleic Acids Research

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 14