Finkbeiner, Steven

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

Klionsky, D. J., Abdelmohsen, K., Abe, A., Abedin, M. J., Abeliovich, H., Acevedo Arozena, A., Adachi, H., Adams, C. M., Adams, P. D., Adeli, K., et al. (2016) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 5,894

Guidelines for the use and interpretation of assays for monitoring autophagy

Klionsky, D. J., Abdalla, F. C., Abeliovich, H., Abraham, R. T., Acevedo-Arozena, A., Adeli, K., Agholme, L., Agnello, M., Agostinis, P., Aguirre-Ghiso, J. A., et al. (2012) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 3,996

Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies

Nalls, M. A., Blauwendraat, C., Vallerga, C. L., Heilbron, K., Bandres-Ciga, S., Chang, D., Tan, M., Kia, D. A., Noyce, A. J., Xue, A., et al. (2019) · The Lancet Neurology

Parkinson's Disease Mechanisms and TreatmentsGenetic Associations and Epidemiology

Cited by 2,454

Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death

Arrasate, M., Mitra, S., Schweitzer, E. S., Segal, M. R., & Finkbeiner, S. (2004) · Nature

Genetic Neurodegenerative DiseasesAmyotrophic Lateral Sclerosis Research

Cited by 1,979

Glutamate Induces Calcium Waves in Cultured Astrocytes: Long-Range Glial Signaling

Cornell-Bell, A. H., Finkbeiner, S. M., Cooper, M. S., & Smith, S. J. (1990) · Science

Neuroscience and Neuropharmacology ResearchConnexins and lens biology

Cited by 1,846

Aberrant excitatory neuronal activity and compensatory remodeling of inhibitory hippocampal circuits in mouse models of alzheimer’s disease.

Palop, J. J., Chin, J., Roberson, E. D., Wang, J., Thwin, M. T., Bien-Ly, N., Yoo, J., Ho, K. O., Yu, G.-Q., Kreitzer, A., et al. (2007) · Neuron

Alzheimer's disease research and treatmentsNeuroscience and Neuropharmacology Research

Cited by 1,653

Ca2+ Influx Regulates BDNF Transcription by a CREB Family Transcription Factor-Dependent Mechanism

Tao, X., Finkbeiner, S., Arnold, D. B., Shaywitz, A. J., & Greenberg, M. E. (1998) · Neuron

Nerve injury and regenerationNeuroscience and Neuropharmacology Research

Cited by 1,561

In Silico Labeling: Predicting Fluorescent Labels in Unlabeled Images

Christiansen, E. M., Yang, S. J., Ando, D. M., Javaherian, A., Skibinski, G., Lipnick, S., Mount, E., O’Neil, A., Shah, K., Lee, A. K., et al. (2018) · Cell

Cell Image Analysis TechniquesAdvanced Fluorescence Microscopy Techniques

Cited by 635

Cytoplasmic Mislocalization of TDP-43 Is Toxic to Neurons and Enhanced by a Mutation Associated with Familial Amyotrophic Lateral Sclerosis

Barmada, S. J., Skibinski, G., Korb, E., Rao, E. J., Wu, J. Y., & Finkbeiner, S. (2010) · The Journal of Neuroscience

Amyotrophic Lateral Sclerosis ResearchAlzheimer's disease research and treatments

Cited by 554

Tau Reduction Prevents Aβ-Induced Defects in Axonal Transport

Vossel, K. A., Zhang, K., Brodbeck, J., Daub, A. C., Sharma, P., Finkbeiner, S., Cui, B., & Mucke, L. (2010) · Science

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 486

Autophagy induction enhances TDP43 turnover and survival in neuronal ALS models

Barmada, S. J., Serio, A., Arjun, A., Bilican, B., Daub, A., Ando, D. M., Tsvetkov, A., Pleiss, M., Li, X., Peisach, D., et al. (2014) · Nature Chemical Biology

Amyotrophic Lateral Sclerosis ResearchAutophagy in Disease and Therapy

Cited by 431

Arc in synaptic plasticity: from gene to behavior

Korb, E., & Finkbeiner, S. (2011) · Trends in Neurosciences

Neuroscience and Neuropharmacology ResearchMemory and Neural Mechanisms

Cited by 388

Astrocyte pathology and the absence of non-cell autonomy in an induced pluripotent stem cell model of TDP-43 proteinopathy

Serio, A., Bilican, B., Barmada, S. J., Ando, D. M., Zhao, C., Siller, R., Burr, K., Haghi, G., Story, D., Nishimura, A. L., et al. (2013) · Proceedings of the National Academy of Sciences

Amyotrophic Lateral Sclerosis ResearchPluripotent Stem Cells Research

Cited by 345

Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerability

Bilican, B., Serio, A., Barmada, S. J., Nishimura, A. L., Sullivan, G. J., Carrasco, M., Phatnani, H. P., Puddifoot, C. A., Story, D., Fletcher, J., et al. (2012) · Proceedings of the National Academy of Sciences

Amyotrophic Lateral Sclerosis ResearchPluripotent Stem Cells Research

Cited by 328

Potential function for the Huntingtin protein as a scaffold for selective autophagy

Ochaba, J., Lukacsovich, T., Csikos, G., Zheng, S., Margulis, J., Salazar, L., Mao, K., Lau, A. L., Yeung, S. Y., Humbert, S., et al. (2014) · Proceedings of the National Academy of Sciences

Genetic Neurodegenerative DiseasesAutophagy in Disease and Therapy

Cited by 308

A small-molecule scaffold induces autophagy in primary neurons and protects against toxicity in a Huntington disease model

Tsvetkov, A. S., Miller, J., Arrasate, M., Wong, J. S., Pleiss, M. A., & Finkbeiner, S. (2010) · Proceedings of the National Academy of Sciences

Autophagy in Disease and TherapyGenetic Neurodegenerative Diseases

Cited by 266

Arc regulates spine morphology and maintains network stability in vivo

Peebles, C. L., Yoo, J., Thwin, M. T., Palop, J. J., Noebels, J. L., & Finkbeiner, S. (2010) · Proceedings of the National Academy of Sciences

Neuroscience and Neuropharmacology ResearchMemory and Neural Mechanisms

Cited by 245

Developmental alterations in Huntington’s disease neural cells and pharmacological rescue in cells and mice

The HD iPSC Consortium, Lim, R. G., Salazar, L. L., Wilton, D. K., King, A. R., Stocksdale, J. T., Sharifabad, D., Lau, A. L., Stevens, B., Reidling, J. C., et al. (2017) · Nature Neuroscience

Genetic Neurodegenerative DiseasesPluripotent Stem Cells Research

Cited by 221

The Autophagy Lysosomal Pathway and Neurodegeneration

Finkbeiner, S. (2020) · Cold Spring Harbor Perspectives in Biology

Autophagy in Disease and TherapyAlzheimer's disease research and treatments

Cited by 196

Proteostasis of polyglutamine varies among neurons and predicts neurodegeneration

Tsvetkov, A. S., Arrasate, M., Barmada, S., Ando, D. M., Sharma, P., Shaby, B. A., & Finkbeiner, S. (2013) · Nature Chemical Biology

Genetic Neurodegenerative DiseasesLysosomal Storage Disorders Research

Cited by 178

Targeting the Intrinsically Disordered Structural Ensemble of α-Synuclein by Small Molecules as a Potential Therapeutic Strategy for Parkinson’s Disease

Tóth, G., Gardai, S. J., Zago, W., Bertoncini, C. W., Cremades, N., Roy, S. L., Tambe, M. A., Rochet, J.-C., Galvagnion, C., Skibinski, G., et al. (2014) · PLoS ONE

Parkinson's Disease Mechanisms and TreatmentsAlzheimer's disease research and treatments

Cited by 151

Amelioration of toxicity in neuronal models of amyotrophic lateral sclerosis by hUPF1

Barmada, S. J., Ju, S., Arjun, A., Batarse, A., Archbold, H. C., Peisach, D., Li, X., Zhang, Y., Tank, E. M. H., Qiu, H., et al. (2015) · Proceedings of the National Academy of Sciences

Amyotrophic Lateral Sclerosis ResearchRNA Research and Splicing

Cited by 125

Cell death assays for neurodegenerative disease drug discovery

Linsley, J. W., Reisine, T., & Finkbeiner, S. (2019) · Expert Opinion on Drug Discovery

Alzheimer's disease research and treatmentsCell death mechanisms and regulation

Cited by 32

A dynamic in vitro model of Down syndrome neurogenesis with trisomy 21 gene dosage correction

Bansal, P., Banda, E. C., Glatt-Deeley, H. R., Stoddard, C. E., Linsley, J. W., Arora, N., Deleschaux, C., Ahern, D. T., Kondaveeti, Y., Massey, R. E., et al. (2024) · Science Advances

Down syndrome and intellectual disability researchPluripotent Stem Cells Research

Cited by 13