Capecchi, Mario R.

Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells

Thomas, K. R., & Capecchi, M. R. (1987) · Cell

CRISPR and Genetic EngineeringAnimal Genetics and Reproduction

Cited by 2,355

Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: A general strategy for targeting mutations to non-selectable genes

Mansour, S. L., Thomas, K. R., & Capecchi, M. R. (1988) · Nature

CRISPR and Genetic EngineeringAnimal Genetics and Reproduction

Cited by 1,683

Sustained in vitro intestinal epithelial culture within a Wnt-dependent stem cell niche

Ootani, A., Li, X., Sangiorgi, E., Ho, Q. T., Ueno, H., Toda, S., Sugihara, H., Fujimoto, K., Weissman, I. L., Capecchi, M. R., et al. (2009) · Nature Medicine

Wnt/β-catenin signaling in development and cancerCancer Cells and Metastasis

Cited by 906

Targeted disruption of the murine int-1 proto-oncogene resulting in severe abnormalities in midbrain and cerebellar development

Thomas, K. R., & Capecchi, M. R. (1990) · Nature

Developmental Biology and Gene RegulationNeurogenesis and neuroplasticity mechanisms

Cited by 896

Hox10 and Hox11 Genes Are Required to Globally Pattern the Mammalian Skeleton

Wellik, D. M., & Capecchi, M. R. (2003) · Science

Developmental Biology and Gene RegulationCongenital limb and hand anomalies

Cited by 586

Retinopathy induced in mice by targeted disruption of the rhodopsin gene

Humphries, M. M., Rancourt, D., Farrar, G. J., Kenna, P., Hazel, M., Bush, R. A., Sieving, P. A., Sheils, D. M., Creighton, P., Erven, A., et al. (1997) · Nature Genetics

Retinal Development and DisordersPhotoreceptor and optogenetics research

Cited by 529

Hematopoietic origin of pathological grooming in Hoxb8 mutant mice

Chen, S.-K., Tvrdik, P., Peden, E., Cho, S., Wu, S., Spangrude, G., & Capecchi, M. R. (2010) · Cell

Obsessive-Compulsive Spectrum DisordersNeuroinflammation and Neurodegeneration Mechanisms

Cited by 450

Hoxb8 Is Required for Normal Grooming Behavior in Mice

Greer, J. M., & Capecchi, M. R. (2002) · Neuron

Obsessive-Compulsive Spectrum DisordersHair Growth and Disorders

Cited by 401

ELOVL2 controls the level of n-6 28:5 and 30:5 fatty acids in testis, a prerequisite for male fertility and sperm maturation in mice

Zadravec, D., Tvrdik, P., Guillou, H., Haslam, R., Kobayashi, T., Napier, J. A., Capecchi, M. R., & Jacobsson, A. (2011) · Journal of Lipid Research

Sperm and Testicular FunctionFatty Acid Research and Health

Cited by 146