Ju, Zhenyu

Cdkn1a deletion improves stem cell function and lifespan of mice with dysfunctional telomeres without accelerating cancer formation

Choudhury, A. R., Ju, Z., Djojosubroto, M. W., Schienke, A., Lechel, A., Schaetzlein, S., Jiang, H., Stepczynska, A., Wang, C., Buer, J., et al. (2007) · Nature Genetics

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 426

A Differentiation Checkpoint Limits Hematopoietic Stem Cell Self-Renewal in Response to DNA Damage

Wang, J., Sun, Q., Morita, Y., Jiang, H., Groß, A., Lechel, A., Hildner, K., Guachalla, L. M., Gompf, A., Hartmann, D., et al. (2012) · Cell

Hematopoietic Stem Cell TransplantationDNA Repair Mechanisms

Cited by 343

The flavonoid procyanidin C1 has senotherapeutic activity and increases lifespan in mice

Xu, Q., Fu, Q., Li, Z., Liu, H., Wang, Y., Lin, X., He, R., Zhang, X., Ju, Z., Campisi, J., et al. (2021) · Nature Metabolism

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 341

Telomere dysfunction induces environmental alterations limiting hematopoietic stem cell function and engraftment

Ju, Z., Jiang, H., Jaworski, M., Rathinam, C., Gompf, A., Klein, C., Trumpp, A., & Rudolph, K. L. (2007) · Nature Medicine

Hematopoietic Stem Cell TransplantationTelomeres, Telomerase, and Senescence

Cited by 284

Telomerase gene mutations are associated with cirrhosis formation

Hartmann, D., Srivastava, U., Thaler, M., Kleinhans, K. N., N'Kontchou, G., Scheffold, A., Bauer, K., Kratzer, R. F., Kloos, N., Katz, S.-F., et al. (2011) · Hepatology

Telomeres, Telomerase, and SenescenceLiver physiology and pathology

Cited by 173

Proteins induced by telomere dysfunction and DNA damage represent biomarkers of human aging and disease

Jiang, H., Schiffer, E., Song, Z., Wang, J., Zürbig, P., Thedieck, K., Moes, S., Bantel, H., Saal, N., Jantos, J., et al. (2008) · Proceedings of the National Academy of Sciences

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 169

Telomere shortening and ageing

Jiang, H., Ju, Z., & Rudolph, K. L. (2007) · Zeitschrift für Gerontologie und Geriatrie

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 165

Lifestyle impacts on the aging-associated expression of biomarkers of DNA damage and telomere dysfunction in human blood

Song, Z., Von Figura, G., Liu, Y., Kraus, J. M., Torrice, C., Dillon, P., Rudolph‐Watabe, M., Ju, Z., Kestler, H. A., Sanoff, H., et al. (2010) · Aging Cell

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 163

Metabolomic profiling of single enlarged lysosomes

Zhu, H., Li, Q., Liao, T., Yin, X., Chen, Q., Wang, Z., Dai, M., Yi, L., Ge, S., Miao, C., et al. (2021) · Nature Methods

Metabolomics and Mass Spectrometry StudiesMass Spectrometry Techniques and Applications

Cited by 103

Aging-induced IL27Ra signaling impairs hematopoietic stem cells

He, H., Xu, P., Zhang, X., Liao, M., Dong, Q., Cong, T., Tang, B., Yang, X., Ye, M., Chang, Y., et al. (2020) · Blood

Hematopoietic Stem Cell TransplantationMesenchymal stem cell research

Cited by 94

Telomerase Deficiency Causes Alveolar Stem Cell Senescence-associated Low-grade Inflammation in Lungs

Chen, R., Zhang, K., Chen, H., Zhao, X., Wang, J., Li, L., Cong, Y., Ju, Z., Xu, D., Williams, B. R. G., et al. (2015) · Journal of Biological Chemistry

Telomeres, Telomerase, and SenescenceInterstitial Lung Diseases and Idiopathic Pulmonary Fibrosis

Cited by 89

A framework of biomarkers for vascular aging: a consensus statement by the Aging Biomarker Consortium

Aging Biomarker Consortium, Zhang, L., Guo, J., Liu, Y., Sun, S., Liu, B., Yang, Q., Tao, J., Tian, X.-L., Pu, J., et al. (2023) · Life Medicine

Cardiovascular Health and Disease PreventionNitric Oxide and Endothelin Effects

Cited by 60

Alterations of the systemic environment are the primary cause of impaired B and T lymphopoiesis in telomere-dysfunctional mice

Song, Z., Wang, J., Guachalla, L. M., Terszowski, G., Rodewald, H.-R., Ju, Z., & Rudolph, K. L. (2010) · Blood

Telomeres, Telomerase, and SenescenceHematopoietic Stem Cell Transplantation

Cited by 53

Sod2 haploinsufficiency does not accelerate aging of telomere dysfunctional mice

Guachalla, L. M., Ju, Z., Koziel, R., von Figura, G., Song, Z., Fusser, M., Epe, B., Jansen-Dűrr, P., & Rudolph, K. L. (2009) · Aging

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 21

A Differentiation Checkpoint Limits Hematopoietic Stem Cell Self-Renewal in Response to DNA Damage

Wang, J., Sun, Q., Morita, Y., Jiang, H., Groß, A., Lechel, A., Hildner, K., Guachalla, L. M., Gompf, A., Hartmann, D., et al. (2014) · Cell

Hematopoietic Stem Cell TransplantationDNA Repair Mechanisms

Cited by 12