Kawaguchi, Riki

Astrocyte scar formation aids central nervous system axon regeneration

Anderson, M. A., Burda, J. E., Ren, Y., Ao, Y., O’Shea, T. M., Kawaguchi, R., Coppola, G., Khakh, B. S., Deming, T. J., & Sofroniew, M. V. (2016) · Nature

Nerve injury and regenerationSpinal Cord Injury Research

Cited by 1,851

A Membrane Receptor for Retinol Binding Protein Mediates Cellular Uptake of Vitamin A

Kawaguchi, R., Yu, J., Honda, J., Hu, J., Whitelegge, J., Ping, P., Wiita, P., Bok, D., & Sun, H. (2007) · Science

Retinoids in leukemia and cellular processesRetinal Development and Disorders

Cited by 836

Molecular basis of astrocyte diversity and morphology across the CNS in health and disease

Endo, F., Kasai, A., Soto, J. S., Yu, X., Qu, Z., Hashimoto, H., Gradinaru, V., Kawaguchi, R., & Khakh, B. S. (2022) · Science

Neuroinflammation and Neurodegeneration MechanismsNeuroscience and Neuropharmacology Research

Cited by 560

Myelin dysfunction drives amyloid-β deposition in models of Alzheimer’s disease

Depp, C., Sun, T., Sasmita, A. O., Spieth, L., Berghoff, S. A., Nazarenko, T., Overhoff, K., Steixner-Kumar, A. A., Subramanian, S., Arinrad, S., et al. (2023) · Nature

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 493

Astrocyte layers in the mammalian cerebral cortex revealed by a single-cell in situ transcriptomic map

Bayraktar, O. A., Bartels, T., Holmqvist, S., Kleshchevnikov, V., Martirosyan, A., Polioudakis, D., Ben Haim, L., Young, A. M. H., Batiuk, M. Y., Prakash, K., et al. (2020) · Nature Neuroscience

Single-cell and spatial transcriptomicsNeurogenesis and neuroplasticity mechanisms

Cited by 489

Molecular signatures underlying neurofibrillary tangle susceptibility in Alzheimer’s disease

Otero-Garcia, M., Mahajani, S. U., Wakhloo, D., Tang, W., Xue, Y.-Q., Morabito, S., Pan, J., Oberhauser, J., Madira, A. E., Shakouri, T., et al. (2022) · Neuron

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 262

Injured adult neurons regress to an embryonic transcriptional growth state

Poplawski, G. H. D., Kawaguchi, R., Van Niekerk, E., Lu, P., Mehta, N., Canete, P., Lie, R., Dragatsis, I., Meves, J. M., Zheng, B., et al. (2020) · Nature

Nerve injury and regenerationSpinal Cord Injury Research

Cited by 247

GDF10 is a signal for axonal sprouting and functional recovery after stroke

Li, S., Nie, E. H., Yin, Y., Benowitz, L. I., Tung, S., Vinters, H. V., Bahjat, F. R., Stenzel-Poore, M. P., Kawaguchi, R., Coppola, G., et al. (2015) · Nature Neuroscience

Nerve injury and regenerationStroke Rehabilitation and Recovery

Cited by 181

Divergent transcriptional regulation of astrocyte reactivity across disorders

Burda, J. E., O’Shea, T. M., Ao, Y., Suresh, K. B., Wang, S., Bernstein, A. M., Chandra, A., Deverasetty, S., Kawaguchi, R., Kim, J. H., et al. (2022) · Nature

Neuroinflammation and Neurodegeneration MechanismsNeuroscience and Neuropharmacology Research

Cited by 164

A comparative analysis of microglial inducible Cre lines

Faust, T. E., Feinberg, P. A., O’Connor, C., Kawaguchi, R., Chan, A., Strasburger, H., Frosch, M., Boyle, M. A., Masuda, T., Amann, L., et al. (2023) · Cell Reports

Neuroinflammation and Neurodegeneration MechanismsCRISPR and Genetic Engineering

Cited by 103

Receptor-mediated cellular uptake mechanism that couples to intracellular storage

Kawaguchi, R., Yu, J., Ter-Stepanian, M., Zhong, M., Cheng, G., Yuan, Q., Jin, M., Travis, G. H., Ong, D., & Sun, H. (2011) · ACS Chemical Biology

Retinoids in leukemia and cellular processesDrug Transport and Resistance Mechanisms

Cited by 91

Retina, retinol, retinal and the natural history of vitamin A as a light sensor

Zhong, M., Kawaguchi, R., Kassai, M., & Sun, H. (2012) · Nutrients

Retinoids in leukemia and cellular processesPhotoreceptor and optogenetics research

Cited by 89

STRA6-Catalyzed Vitamin A Influx, Efflux, and Exchange

Kawaguchi, R., Zhong, M., Kassai, M., Ter-Stepanian, M., & Sun, H. (2012) · The Journal of Membrane Biology

Retinoids in leukemia and cellular processesCholesterol and Lipid Metabolism

Cited by 82

Vitamin A Transport Mechanism of the Multitransmembrane Cell-Surface Receptor STRA6

Kawaguchi, R., Zhong, M., Kassai, M., Ter-Stepanian, M., & Sun, H. (2015) · Membranes

Retinoids in leukemia and cellular processesDrug Transport and Resistance Mechanisms

Cited by 75

An Essential Ligand-binding Domain in the Membrane Receptor for Retinol-binding Protein Revealed by Large-scale Mutagenesis and a Human Polymorphism

Kawaguchi, R., Yu, J., Wiita, P., Honda, J., & Sun, H. (2008) · Journal of Biological Chemistry

Retinoids in leukemia and cellular processesRetinal Development and Disorders

Cited by 70

2-Deoxyglucose drives plasticity via an adaptive ER stress-ATF4 pathway and elicits stroke recovery and Alzheimer’s resilience

Kumar, A., Karuppagounder, S. S., Chen, Y., Corona, C., Kawaguchi, R., Cheng, Y., Balkaya, M., Sagdullaev, B. T., Wen, Z., Stuart, C., et al. (2023) · Neuron

Endoplasmic Reticulum Stress and DiseaseDietary Effects on Health

Cited by 64

4D marmoset brain map reveals MRI and molecular signatures for onset of multiple sclerosis–like lesions

Lin, J.-P., Brake, A., Donadieu, M., Lee, A., Smith, G., Hu, K., Nair, G., Kawaguchi, R., Sati, P., Geschwind, D. H., et al. (2025) · Science

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 35