Lee, Virginia M.-Y.

Multimodal evaluation demonstrates in vivo 18F-AV-1451 uptake in autopsy-confirmed corticobasal degeneration

McMillan, C. T., Irwin, D. J., Nasrallah, I., Phillips, J. S., Spindler, M., Rascovsky, K., Ternes, K., Jester, C., Wolk, D. A., Kwong, L. K., et al. (2016) · Acta Neuropathologica

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 87

The role of tau in Alzheimer's disease

Trojanowski, J. Q., & Lee, V. M.-Y. (2002) · Medical Clinics of North America

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 85

O-GlcNAc forces an α-synuclein amyloid strain with notably diminished seeding and pathology

Balana, A. T., Mahul-Mellier, A.-L., Nguyen, B. A., Horvath, M., Javed, A., Hard, E. R., Jasiqi, Y., Singh, P., Afrin, S., Pedretti, R., et al. (2024) · Nature Chemical Biology

Parkinson's Disease Mechanisms and TreatmentsAlzheimer's disease research and treatments

Cited by 84

The Sigma-2 Receptor/TMEM97, PGRMC1, and LDL Receptor Complex Are Responsible for the Cellular Uptake of Aβ42 and Its Protein Aggregates

Riad, A., Lengyel-Zhand, Z., Zeng, C., Weng, C.-C., Lee, V. M.-Y., Trojanowski, J. Q., & Mach, R. H. (2020) · Molecular Neurobiology

Alzheimer's disease research and treatmentsPharmacological Receptor Mechanisms and Effects

Cited by 81

Quantification of Modified Amyloid β Peptides in Alzheimer Disease and Down Syndrome Brains

Hosoda, R., Saido, T. C., Otvos, L., Arai, T., Mann, D. M. A., Lee, V. M.-Y., Trojanowski, J. Q., & Iwatsubo, T. (1998) · Journal of Neuropathology and Experimental Neurology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 79

Novel Method to Quantify Neuropil Threads in Brains from Elders With or Without Cognitive Impairment

Mitchell, T. W., Nissanov, J., Han, L.-Y., Mufson, E. J., Schneider, J. A., Cochran, E. J., Bennett, D. A., Lee, V. M.-Y., Trojanowski, J. Q., & Arnold, S. E. (2000) · Journal of Histochemistry & Cytochemistry

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 78

Genome-wide, high-content siRNA screening identifies the Alzheimer’s genetic risk factor FERMT2 as a major modulator of APP metabolism

ADGC, A. D. N. I., Chapuis, J., Flaig, A., Grenier-Boley, B., Eysert, F., Pottiez, V., Deloison, G., Vandeputte, A., Ayral, A.-M., Mendes, T., et al. (2017) · Acta Neuropathologica

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 75

In vivo measurement of glutamate loss is associated with synapse loss in a mouse model of tauopathy

Crescenzi, R., DeBrosse, C., Nanga, R. P. R., Reddy, S., Haris, M., Hariharan, H., Iba, M., Lee, V. M. Y., Detre, J. A., Borthakur, A., et al. (2014) · NeuroImage

Alzheimer's disease research and treatmentsAdvanced MRI Techniques and Applications

Cited by 73

Reduction of Detyrosinated Microtubules and Golgi Fragmentation Are Linked to Tau-Induced Degeneration in Astrocytes

Yoshiyama, Y., Zhang, B., Bruce, J., Trojanowski, J. Q., & Lee, V. M.-Y. (2003) · The Journal of Neuroscience

Alzheimer's disease research and treatmentsMicrotubule and mitosis dynamics

Cited by 72

Measurements of auto‐antibodies to α‐synuclein in the serum and cerebral spinal fluids of patients with Parkinson's disease

Akhtar, R. S., Licata, J. P., Luk, K. C., Shaw, L. M., Trojanowski, J. Q., & Lee, V. M. ‐. (2018) · Journal of Neurochemistry

Parkinson's Disease Mechanisms and TreatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 60

Cognitive, neuroimaging, and pathological studies in a patient with Pick's disease

Lieberman, A. P., Trojanowski, J. Q., Lee, V. M. ‐., Balin, B. J., Ding, X., Greenberg, J., Morrison, D., Reivich, M., & Grossman, M. (1998) · Annals of Neurology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 54

GFP-Mutant Human Tau Transgenic Mice Develop Tauopathy Following CNS Injections of Alzheimer's Brain-Derived Pathological Tau or Synthetic Mutant Human Tau Fibrils

Gibbons, G. S., Banks, R. A., Kim, B., Xu, H., Changolkar, L., Leight, S. N., Riddle, D. M., Li, C., Gathagan, R. J., Brown, H. J., et al. (2017) · The Journal of Neuroscience

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 53

High copy wildtype human 1N4R tau expression promotes early pathological tauopathy accompanied by cognitive deficits without progressive neurofibrillary degeneration

Wheeler, J. M., McMillan, P. J., Hawk, M., Iba, M., Robinson, L., Xu, G. J., Dombroski, B. A., Jeong, D., Dichter, M. A., Juul, H., et al. (2015) · Acta Neuropathologica Communications

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 31

Genetic studies of plasma analytes identify novel potential biomarkers for several complex traits

Deming, Y., Xia, J., Cai, Y., Lord, J., Del-Aguila, J. L., Fernandez, M. V., Carrell, D., Black, K., Budde, J., Ma, S., et al. (2016) · Scientific Reports

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 28

Deep learning to quantify the pace of brain aging in relation to neurocognitive changes

Yin, C., Imms, P., Chowdhury, N. F., Chaudhari, N. N., Ping, H., Wang, H., Bogdan, P., Irimia, A., Initiative, T. A. D. N., Weiner, M., et al. (2025) · Proceedings of the National Academy of Sciences

Dementia and Cognitive Impairment ResearchAdvanced MRI Techniques and Applications

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