Sims, Peter A.

Immune and genomic correlates of response to anti-PD-1 immunotherapy in glioblastoma

Zhao, J., Chen, A. X., Gartrell, R. D., Silverman, A. M., Aparicio, L., Chu, T., Bordbar, D., Shan, D., Samanamud, J., Mahajan, A., et al. (2019) · Nature Medicine

Cancer Immunotherapy and BiomarkersGlioma Diagnosis and Treatment

Cited by 903

Single-cell transcriptomics of human T cells reveals tissue and activation signatures in health and disease

Szabo, P. A., Levitin, H. M., Miron, M., Snyder, M. E., Senda, T., Yuan, J., Cheng, Y. L., Bush, E. C., Dogra, P., Thapa, P., et al. (2019) · Nature Communications

Single-cell and spatial transcriptomicsT-cell and B-cell Immunology

Cited by 756

Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations

Affo, S., Nair, A., Brundu, F., Ravichandra, A., Bhattacharjee, S., Matsuda, M., Chin, L., Filliol, A., Wen, W., Song, X., et al. (2021) · Cancer Cell

Cholangiocarcinoma and Gallbladder Cancer StudiesLiver physiology and pathology

Cited by 416

Tumor restriction by type I collagen opposes tumor-promoting effects of cancer-associated fibroblasts

Bhattacharjee, S., Hamberger, F., Ravichandra, A., Miller, M., Nair, A., Affo, S., Filliol, A., Chin, L., Savage, T. M., Yin, D., et al. (2021) · Journal of Clinical Investigation

Cancer Cells and MetastasisCellular Mechanics and Interactions

Cited by 367

Digital RNA sequencing minimizes sequence-dependent bias and amplification noise with optimized single-molecule barcodes

Shiroguchi, K., Jia, T. Z., Sims, P. A., & Xie, X. S. (2012) · Proceedings of the National Academy of Sciences

Genomics and Phylogenetic StudiesSingle-cell and spatial transcriptomics

Cited by 276

Single-Cell Analysis of Regional Differences in Adult V-SVZ Neural Stem Cell Lineages

Mizrak, D., Levitin, H. M., Delgado, A. C., Crotet, V., Yuan, J., Chaker, Z., Silva-Vargas, V., Sims, P. A., & Doetsch, F. (2019) · Cell Reports

Neurogenesis and neuroplasticity mechanismsSingle-cell and spatial transcriptomics

Cited by 248

Human memory T cells with a naive phenotype accumulate with aging and respond to persistent viruses

Pulko, V., Davies, J. S., Martinez, C., Lanteri, M. C., Busch, M. P., Diamond, M. S., Knox, K., Bush, E. C., Sims, P. A., Sinari, S., et al. (2016) · Nature Immunology

T-cell and B-cell ImmunologyImmunotherapy and Immune Responses

Cited by 175

Ribosome Profiling Reveals a Cell-Type-Specific Translational Landscape in Brain Tumors

Gonzalez, C., Sims, J. S., Hornstein, N., Mela, A., Garcia, F., Lei, L., Gass, D. A., Amendolara, B., Bruce, J. N., Canoll, P., et al. (2014) · Journal of Neuroscience

RNA and protein synthesis mechanismsGlioma Diagnosis and Treatment

Cited by 116

Pre-clinical validation of an RNA-based precision oncology platform for patient-therapy alignment in a diverse set of human malignancies resistant to standard treatments

Mundi, P. S., Dela Cruz, F. S., Grunn, A., Diolaiti, D., Mauguen, A., Rainey, A. R., Guillan, K. C., Siddiquee, A., You, D., Realubit, R., et al. (2021) · Cancer Discovery

Computational Drug Discovery MethodsCancer Genomics and Diagnostics

Cited by 51

ADTnorm: Robust Integration of Single-cell Protein Measurement across CITE-seq Datasets

Zheng, Y., Caron, D. P., Kim, J. Y., Jun, S.-H., Tian, Y., Florian, M., Stuart, K. D., Sims, P. A., & Gottardo, R. (2022) · Nature Communications

Single-cell and spatial transcriptomicsGene expression and cancer classification

Cited by 18