Koole, Michel

Quantifying SV2A density and drug occupancy in the human brain using [11C]UCB-J PET imaging and subcortical white matter as reference tissue

Koole, M., van Aalst, J., Devrome, M., Mertens, N., Serdons, K., Lacroix, B., Mercier, J., Sciberras, D., Maguire, P., & Van Laere, K. (2019) · European Journal of Nuclear Medicine and Molecular Imaging

Medical Imaging Techniques and ApplicationsNeurotransmitter Receptor Influence on Behavior

Cited by 118

In vivo synaptic density loss is related to tau deposition in amnestic mild cognitive impairment

Vanhaute, H., Ceccarini, J., Michiels, L., Koole, M., Sunaert, S., Lemmens, R., Triau, E., Emsell, L., Vandenbulcke, M., & Van Laere, K. (2020) · Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 88

Synaptic density in healthy human aging is not influenced by age or sex: a 11C-UCB-J PET study

Michiels, L., Delva, A., van Aalst, J., Ceccarini, J., Vandenberghe, W., Vandenbulcke, M., Koole, M., Lemmens, R., & Laere, K. V. (2021) · NeuroImage

Dementia and Cognitive Impairment ResearchMedical Imaging Techniques and Applications

Cited by 59

Noise reduction using a Bayesian penalized-likelihood reconstruction algorithm on a time-of-flight PET-CT scanner

Caribé, P. R. R. V., Koole, M., D’Asseler, Y., Van Den Broeck, B., & Vandenberghe, S. (2019) · EJNMMI Physics

Medical Imaging Techniques and ApplicationsImage and Signal Denoising Methods

Cited by 51

Spatial decrease of synaptic density in amnestic mild cognitive impairment follows the tau build-up pattern

Vanderlinden, G., Ceccarini, J., Vande Casteele, T., Michiels, L., Lemmens, R., Triau, E., Serdons, K., Tournoy, J., Koole, M., Vandenbulcke, M., et al. (2022) · Molecular Psychiatry

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 47

Equivalent Dynamic Human Brain NK1-Receptor Occupancy Following Single-Dose i.v. Fosaprepitant vs. Oral Aprepitant as Assessed by PET Imaging

Van Laere, K., De Hoon, J., Bormans, G., Koole, M., Derdelinckx, I., De Lepeleire, I., Declercq, R., Sanabria Bohorquez, S. M., Hamill, T., Mozley, P. D., et al. (2012) · Clinical Pharmacology & Therapeutics

Nausea and vomiting managementPharmacogenetics and Drug Metabolism

Cited by 46

Micro-Positron Emission Tomography Imaging of Rat Brain Metabolism during Expression of Contextual Conditioning

Luyten, L., Casteels, C., Vansteenwegen, D., van Kuyck, K., Koole, M., Van Laere, K., & Nuttin, B. (2012) · The Journal of Neuroscience

Memory and Neural MechanismsNeurotransmitter Receptor Influence on Behavior

Cited by 39

Preliminary evidence for preserved synaptic density in late-life depression

Vande Casteele, T., Laroy, M., Van Cauwenberge, M., Koole, M., Dupont, P., Sunaert, S., Van den Stock, J., Bouckaert, F., Van Laere, K., Emsell, L., et al. (2024) · Translational Psychiatry

Treatment of Major DepressionDementia and Cognitive Impairment Research

Cited by 14