Schwandt, Melanie

Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

23andMe Research Team, Walters, R. K., Polimanti, R., Johnson, E. C., McClintick, J. N., Adams, M. J., Adkins, A. E., Aliev, F., Bacanu, S.-A., Batzler, A., et al. (2018) · Nature Neuroscience

Genetic Associations and EpidemiologySubstance Abuse Treatment and Outcomes

Cited by 632

Rearing condition and rh5-HTTLPR interact to influence limbic-hypothalamic-pituitary-adrenal axis response to stress in infant macaques

Barr, C. S., Newman, T. K., Shannon, C., Parker, C., Dvoskin, R. L., Becker, M. L., Schwandt, M., Champoux, M., Lesch, K. P., Goldman, D., et al. (2004) · Biological Psychiatry

Stress Responses and CortisolNeurotransmitter Receptor Influence on Behavior

Cited by 385

Multivariate genome-wide association meta-analysis of over 1 million subjects identifies loci underlying multiple substance use disorders

Hatoum, A. S., Colbert, S. M. C., Johnson, E. C., Huggett, S. B., Deak, J. D., Pathak, G. A., Jennings, M. V., Paul, S. E., Karcher, N. R., Hansen, I., et al. (2023) · Nature Mental Health

Genetic Associations and EpidemiologySubstance Abuse Treatment and Outcomes

Cited by 241

Variation at the mu-opioid receptor gene ( OPRM1 ) influences attachment behavior in infant primates

Barr, C. S., Schwandt, M. L., Lindell, S. G., Higley, J. D., Maestripieri, D., Goldman, D., Suomi, S. J., & Heilig, M. (2008) · Proceedings of the National Academy of Sciences

Neuroendocrine regulation and behaviorNeurotransmitter Receptor Influence on Behavior

Cited by 191

The CRF1 antagonist verucerfont in anxious alcohol-dependent women: translation of neuroendocrine, but not of anti-craving effects

Schwandt, M. L., Cortes, C. R., Kwako, L. E., George, D. T., Momenan, R., Sinha, R., Grigoriadis, D. E., Pich, E. M., Leggio, L., & Heilig, M. (2016) · Neuropsychopharmacology

Substance Abuse Treatment and OutcomesStress Responses and Cortisol

Cited by 159

The glucagon-like peptide-1 receptor as a potential treatment target in alcohol use disorder: evidence from human genetic association studies and a mouse model of alcohol dependence

Suchankova, P., Yan, J., Schwandt, M. L., Stangl, B. L., Caparelli, E. C., Momenan, R., Jerlhag, E., Engel, J. A., Hodgkinson, C. A., Egli, M., et al. (2015) · Translational Psychiatry

Neurotransmitter Receptor Influence on BehaviorSubstance Abuse Treatment and Outcomes

Cited by 146

Effect of Acamprosate on Magnetic Resonance Spectroscopy Measures of Central Glutamate in Detoxified Alcohol-Dependent Individuals: A Randomized Controlled Experimental Medicine Study

Umhau, J. C., Momenan, R., Schwandt, M. L., Singley, E., Lifshitz, M., Doty, L., Adams, L. J., Vengeliene, V., Spanagel, R., Zhang, Y., et al. (2010) · Archives of General Psychiatry

Substance Abuse Treatment and OutcomesNeurotransmitter Receptor Influence on Behavior

Cited by 144

Neurofunctional domains derived from deep behavioral phenotyping in alcohol use disorder

Kwako, L. E., Schwandt, M. L., Ramchandani, V. A., Diazgranados, N., Koob, G. F., Volkow, N. D., Blanco, C., & Goldman, D. (2019) · American Journal of Psychiatry

Substance Abuse Treatment and OutcomesNeurotransmitter Receptor Influence on Behavior

Cited by 138

The novel ghrelin receptor inverse agonist PF-5190457 administered with alcohol: Preclinical safety experiments and a phase 1b human laboratory study

Lee, M. R., Tapocik, J. D., Ghareeb, M., Schwandt, M. L., Dias, A. A., Le, A. N., Cobbina, E., Farinelli, L. A., Bouhlal, S., Farokhnia, M., et al. (2020) · Molecular Psychiatry

Regulation of Appetite and ObesityAlcohol Consumption and Health Effects

Cited by 129

Impact of multiple types of childhood trauma exposure on risk of psychiatric comorbidity among alcoholic inpatients

Huang, M., Schwandt, M. L., Ramchandani, V. A., George, D. T., & Heilig, M. (2012) · Alcoholism: Clinical and Experimental Research

Child Abuse and TraumaPosttraumatic Stress Disorder Research

Cited by 116

Association of a Functional Polymorphism in the μ-Opioid Receptor Gene With Alcohol Response and Consumption in Male Rhesus Macaques

Barr, C. S., Schwandt, M., Lindell, S. G., Chen, S. A., Goldman, D., Suomi, S. J., Higley, J. D., & Heilig, M. (2007) · Archives of General Psychiatry

Neurotransmitter Receptor Influence on BehaviorNeuropeptides and Animal Physiology

Cited by 105

Reversibility of object recognition but not spatial memory impairment following binge-like alcohol exposure in rats

Cippitelli, A., Zook, M., Bell, L., Damadzic, R., Eskay, R. L., Schwandt, M., & Heilig, M. (2010) · Neurobiology of Learning and Memory

Memory and Neural MechanismsPrenatal Substance Exposure Effects

Cited by 44

Lack of target engagement following low-frequency deep transcranial magnetic stimulation of the anterior insula

Spagnolo, P. A., Wang, H., Srivanitchapoom, P., Schwandt, M., Heilig, M., & Hallett, M. (2019) · Neuromodulation Technology at the Neural Interface

Transcranial Magnetic Stimulation StudiesDeep Brain Stimulation and Movement Disorders

Cited by 39

Defining the role of corticotropin releasing factor binding protein in alcohol consumption

Haass-Koffler, C. L., Henry, A. T., Melkus, G., Simms, J. A., Naemmuddin, M., Nielsen, C. K., Lasek, A. W., Magill, M., Schwandt, M. L., Momenan, R., et al. (2016) · Translational Psychiatry

Neurotransmitter Receptor Influence on BehaviorNeuropeptides and Animal Physiology

Cited by 33

Effect of alcohol use disorder on oxytocin peptide and receptor mRNA expression in human brain: a post-mortem case-control study

Lee, M. R., Schwandt, M. L., Sankar, V., Suchankova, P., Sun, H., & Leggio, L. (2017) · Psychoneuroendocrinology

Neuroendocrine regulation and behaviorNeurotransmitter Receptor Influence on Behavior

Cited by 33

Differential association between the GLP1R gene variants and brain functional connectivity according to the severity of alcohol use

Farokhnia, M., Fede, S. J., Grodin, E. N., Browning, B. D., Crozier, M. E., Schwandt, M. L., Hodgkinson, C. A., Momenan, R., & Leggio, L. (2022) · Scientific Reports

Neurotransmitter Receptor Influence on BehaviorFunctional Brain Connectivity Studies

Cited by 32

Severity of alcohol use disorder influences sex differences in sleep, mood, and brain functional connectivity impairments

Zhang, R., Wiers, C. E., Manza, P., Tomasi, D., Shokri-Kojori, E., Kerich, M., Almira, E., Schwandt, M., Diazgranados, N., Momenan, R., et al. (2022) · Brain Communications

Functional Brain Connectivity StudiesSubstance Abuse Treatment and Outcomes

Cited by 11