Lohmueller, Kirk E.

Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease

Lohmueller, K. E., Pearce, C. L., Pike, M., Lander, E. S., & Hirschhorn, J. N. (2003) · Nature Genetics

Genetic Associations and EpidemiologyMeta-analysis and systematic reviews

Cited by 1,900

A comprehensive review of genetic association studies

Hirschhorn, J. N., Lohmueller, K., Byrne, E., & Hirschhorn, K. (2002) · Genetics in Medicine

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 1,674

An aboriginal Australian genome reveals separate human dispersals into Asia

Rasmussen, M., Guo, X., Wang, Y., Lohmueller, K. E., Rasmussen, S., Albrechtsen, A., Skotte, L., Lindgreen, S., Metspalu, M., Jombart, T., et al. (2011) · Science

Forensic and Genetic ResearchPleistocene-Era Hominins and Archaeology

Cited by 787

Assessing the evolutionary impact of amino acid mutations in the human genome.

Boyko, A. R., Williamson, S. H., Indap, A. R., Degenhardt, J. D., Hernandez, R. D., Lohmueller, K. E., Adams, M. D., Schmidt, S., Sninsky, J. J., Sunyaev, S. R., et al. (2008) · PLoS Genetics

Evolution and Genetic DynamicsForensic and Genetic Research

Cited by 628

Bottlenecks and Selective Sweeps during Domestication Have Increased Deleterious Genetic Variation in Dogs

Marsden, C. D., Ortega-Del Vecchyo, D., O’Brien, D. P., Taylor, J. F., Ramirez, O., Vilà, C., Marques-Bonet, T., Schnabel, R. D., Wayne, R. K., & Lohmueller, K. E. (2016) · Proceedings of the National Academy of Sciences

Genetic and phenotypic traits in livestockEvolution and Genetic Dynamics

Cited by 333

Genomic signatures of extensive inbreeding in Isle Royale wolves, a population on the threshold of extinction

Robinson, J. A., Räikkönen, J., Vucetich, L. M., Vucetich, J. A., Peterson, R. O., Lohmueller, K. E., & Wayne, R. K. (2019) · Science Advances

Genetic diversity and population structureGenetic and phenotypic traits in livestock

Cited by 317

Strongly deleterious mutations are a primary determinant of extinction risk due to inbreeding depression

Kyriazis, C. C., Wayne, R. K., & Lohmueller, K. E. (2021) · Evolution Letters

Genetic diversity and population structureEvolution and Genetic Dynamics

Cited by 280

Purging of Strongly Deleterious Mutations Explains Long-Term Persistence and Absence of Inbreeding Depression in Island Foxes

Robinson, J. A., Brown, C., Kim, B. Y., Lohmueller, K. E., & Wayne, R. K. (2018) · Current Biology

Genetic diversity and population structureEvolution and Genetic Dynamics

Cited by 221

Patterns of de novo tandem repeat mutations and their role in autism

Mitra, I., Huang, B., Mousavi, N., Ma, N., Lamkin, M., Yanicky, R., Shleizer-Burko, S., Lohmueller, K. E., & Gymrek, M. (2021) · Nature

Autism Spectrum Disorder ResearchGenomic variations and chromosomal abnormalities

Cited by 194

The distribution of deleterious genetic variation in human populations

Lohmueller, K. E. (2014) · Current Opinion in Genetics & Development

Evolution and Genetic DynamicsGenetic Associations and Epidemiology

Cited by 131

Selection and Reduced Population Size Cannot Explain Higher Amounts of Neandertal Ancestry in East Asian than in European Human Populations

Kim, B. Y., & Lohmueller, K. E. (2015) · The American Journal of Human Genetics

Pleistocene-Era Hominins and ArchaeologyForensic and Genetic Research

Cited by 82

Evolutionary History, Selective Sweeps, and Deleterious Variation in the Dog

Freedman, A. H., Lohmueller, K. E., & Wayne, R. K. (2016) · Annual Review of Ecology, Evolution, and Systematics

Genetic and phenotypic traits in livestockHuman-Animal Interaction Studies

Cited by 50

Determining the Effect of Natural Selection on Linked Neutral Divergence across Species

Phung, T. N., Huber, C. D., & Lohmueller, K. E. (2016) · PLOS Genetics

Evolution and Genetic DynamicsGenetic diversity and population structure

Cited by 45

The Impact of Recessive Deleterious Variation on Signals of Adaptive Introgression in Human Populations

Zhang, X., Kim, B., Lohmueller, K. E., & Huerta-Sánchez, E. (2020) · Genetics

Pleistocene-Era Hominins and ArchaeologyForensic and Genetic Research

Cited by 35

MaLAdapt Reveals Novel Targets of Adaptive Introgression From Neanderthals and Denisovans in Worldwide Human Populations

Zhang, X., Kim, B., Singh, A., Sankararaman, S., Durvasula, A., & Lohmueller, K. E. (2023) · Molecular Biology and Evolution

Forensic and Genetic ResearchPleistocene-Era Hominins and Archaeology

Cited by 29

A signature of Neanderthal introgression on molecular mechanisms of environmental responses

Findley, A. S., Zhang, X., Boye, C., Lin, Y. L., Kalita, C. A., Barreiro, L., Lohmueller, K. E., Pique-Regi, R., & Luca, F. (2021) · PLoS Genetics

Pleistocene-Era Hominins and ArchaeologyGenetic Associations and Epidemiology

Cited by 14

Inference of the Demographic Histories and Selective Effects of Human Gut Commensal Microbiota Over the Course of Human History

Mah, J. C., Lohmueller, K. E., & Garud, N. R. (2025) · Molecular Biology and Evolution

Evolution and Genetic DynamicsGut microbiota and health

Cited by 11

The impact of identity-by-descent on fitness and disease in natural and domesticated Canid populations

Mooney, J. A., Yohannes, A., & Lohmueller, K. E. (2020) · bioRxiv (Cold Spring Harbor Laboratory)

Genetic and phenotypic traits in livestockHuman-Animal Interaction Studies

Cited by 1