Bouillet, Philippe

Proapoptotic Bcl-2 Relative Bim Required for Certain Apoptotic Responses, Leukocyte Homeostasis, and to Preclude Autoimmunity

Bouillet, P., Metcalf, D., Huang, D. C. S., Tarlinton, D. M., Kay, T. W. H., Köntgen, F., Adams, J. M., & Strasser, A. (1999) · Science

Cell death mechanisms and regulationT-cell and B-cell Immunology

Cited by 1,504

BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes

Bouillet, P., Purton, J. F., Godfrey, D. I., Zhang, L.-C., Coultas, L., Puthalakath, H., Pellegrini, M., Cory, S., Adams, J. M., & Strasser, A. (2002) · Nature

Cell death mechanisms and regulationT-cell and B-cell Immunology

Cited by 782

Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome

Marsden, V. S., O'Connor, L., O'Reilly, L. A., Silke, J., Metcalf, D., Ekert, P. G., Huang, D. C. S., Cecconi, F., Kuida, K., Tomaselli, K. J., et al. (2002) · Nature

Cell death mechanisms and regulationCancer-related Molecular Pathways

Cited by 578

XIAP discriminates between type I and type II FAS-induced apoptosis

Jost, P. J., Grabow, S., Gray, D., McKenzie, M. D., Nachbur, U., Huang, D. C. S., Bouillet, P., Thomas, H. E., Borner, C., Silke, J., et al. (2009) · Nature

Cell death mechanisms and regulationCancer-related Molecular Pathways

Cited by 482

Membrane-bound Fas ligand only is essential for Fas-induced apoptosis

O’ Reilly, L. A., Tai, L., Lee, L., Kruse, E. A., Grabow, S., Fairlie, W. D., Haynes, N. M., Tarlinton, D. M., Zhang, J.-G., Belz, G. T., et al. (2009) · Nature

Cell death mechanisms and regulationT-cell and B-cell Immunology

Cited by 400

Loss of the pro-apoptotic BH3-only Bcl-2 family member Bim inhibits BCR stimulation-induced apoptosis and deletion of autoreactive B cells

Enders, A., Bouillet, P., Puthalakath, H., Xu, Y., Tarlinton, D. M., & Strasser, A. (2003) · The Journal of Experimental Medicine

Cell death mechanisms and regulationT-cell and B-cell Immunology

Cited by 295

BIM Regulates Apoptosis during Mammary Ductal Morphogenesis, and Its Absence Reveals Alternative Cell Death Mechanisms

Mailleux, A. A., Overholtzer, M., Schmelzle, T., Bouillet, P., Strasser, A., & Brugge, J. S. (2007) · Developmental Cell

Cell death mechanisms and regulationDevelopmental Biology and Gene Regulation

Cited by 255

Developmental expression pattern of Stra6, a retinoic acid-responsive gene encoding a new type of membrane protein

Bouillet, P., Sapin, V., Chazaud, C., Messaddeq, N., Décimo, D., Dollé, P., & Chambon, P. (1997) · Mechanisms of Development

Retinoids in leukemia and cellular processesPeroxisome Proliferator-Activated Receptors

Cited by 209

VDAC2 enables BAX to mediate apoptosis and limit tumor development

Chin, H. S., Li, M. X., Tan, I. K. L., Ninnis, R. L., Reljic, B., Scicluna, K., Dagley, L. F., Sandow, J. J., Kelly, G. L., Samson, A. L., et al. (2018) · Nature Communications

Cell death mechanisms and regulationMitochondrial Function and Pathology

Cited by 196

Intrahepatic Murine CD8 T-Cell Activation Associates With a Distinct Phenotype Leading to Bim-Dependent Death

Holz, L. E., Benseler, V., Bowen, D. G., Bouillet, P., Strasser, A., O'Reilly, L., d'Avigdor, W. M. H., Bishop, A. G., McCaughan, G. W., & Bertolino, P. (2008) · Gastroenterology

T-cell and B-cell ImmunologyHepatitis B Virus Studies

Cited by 127

BCL-2 family member BOK is widely expressed but its loss has only minimal impact in mice

Ke, F., Voss, A., Kerr, J. B., O'Reilly, L. A., Tai, L., Echeverry, N., Bouillet, P., Strasser, A., & Kaufmann, T. (2012) · Cell Death & Differentiation

Cell death mechanisms and regulationCancer-related Molecular Pathways

Cited by 113

BCL-2 is dispensable for thrombopoiesis and platelet survival

Debrincat, M. A., Pleines, I., Lebois, M., Lane, R. M., Holmes, M. L., Corbin, J., Vandenberg, C. J., Alexander, W. S., Ng, A. P., Strasser, A., et al. (2015) · Cell Death & Disease

Platelet Disorders and TreatmentsCell death mechanisms and regulation

Cited by 92

Consequences of the combined loss of BOK and BAK or BOK and BAX

Ke, F., Bouillet, P., Kaufmann, T., Strasser, A., Kerr, J., & Voss, A. K. (2013) · Cell Death & Disease

Cell death mechanisms and regulationAutophagy in Disease and Therapy

Cited by 72

Destruction of tumor vasculature and abated tumor growth upon VEGF blockade is driven by proapoptotic protein Bim in endothelial cells

Naik, E., O'Reilly, L. A., Asselin-Labat, M.-L., Merino, D., Lin, A., Cook, M., Coultas, L., Bouillet, P., Adams, J. M., & Strasser, A. (2011) · Journal of Experimental Medicine

Angiogenesis and VEGF in CancerCell death mechanisms and regulation

Cited by 31