Eckardt, Kai-Uwe

The definition, classification, and prognosis of chronic kidney disease: a KDIGO Controversies Conference report

Levey, A. S., de Jong, P. E., Coresh, J., El Nahas, M., Astor, B. C., Matsushita, K., Gansevoort, R. T., Kasiske, B. L., & Eckardt, K.-U. (2011) · Kidney International

Chronic Kidney Disease and DiabetesAcute Kidney Injury Research

Cited by 2,345

A trial of darbepoetin alfa in type 2 diabetes and chronic kidney disease

Pfeffer, M. A., Burdmann, E. A., Chen, C.-Y., Cooper, M. E., de Zeeuw, D., Eckardt, K.-U., Feyzi, J. M., Ivanovich, P., Kewalramani, R., Levey, A. S., et al. (2009) · New England Journal of Medicine

Erythropoietin and Anemia TreatmentDialysis and Renal Disease Management

Cited by 2,096

Evolving importance of kidney disease: from subspecialty to global health burden

Eckardt, K.-U., Coresh, J., Devuyst, O., Johnson, R. J., Köttgen, A., Levey, A. S., & Levin, A. (2013) · The Lancet

Chronic Kidney Disease and DiabetesAcute Kidney Injury Research

Cited by 1,159

Hypoxia promotes fibrogenesis in vivo via HIF-1 stimulation of epithelial-to-mesenchymal transition

Higgins, D. F., Kimura, K., Bernhardt, W. M., Shrimanker, N., Akai, Y., Hohenstein, B., Saito, Y., Johnson, R. S., Kretzler, M., Cohen, C. D., et al. (2007) · Journal of Clinical Investigation

Chronic Kidney Disease and DiabetesAcute Kidney Injury Research

Cited by 976

Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

Mahajan, A., Spracklen, C. N., Zhang, W., Ng, M. C. Y., Petty, L. E., Kitajima, H., Yu, G. Z., Rüeger, S., Speidel, L., Kim, Y. J., et al. (2022) · Nature Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 704

Genetic drivers of heterogeneity in type 2 diabetes pathophysiology

Suzuki, K., Hatzikotoulas, K., Southam, L., Taylor, H. J., Yin, X., Lorenz, K. M., Mandla, R., Huerta-Chagoya, A., Melloni, G. E. M., Kanoni, S., et al. (2024) · Nature

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 606

Change in albuminuria and GFR as end points for clinical trials in early stages of CKD: a scientific workshop sponsored by the National Kidney Foundation in collaboration with the US Food and Drug Administration and European Medicines Agency

Levey, A. S., Gansevoort, R. T., Coresh, J., Inker, L. A., Heerspink, H. L., Grams, M. E., Greene, T., Tighiouart, H., Matsushita, K., Ballew, S. H., et al. (2020) · American Journal of Kidney Diseases

Chronic Kidney Disease and DiabetesStatistical Methods in Clinical Trials

Cited by 591

Everolimus in Patients with Autosomal Dominant Polycystic Kidney Disease

Walz, G., Budde, K., Mannaa, M., Nürnberger, J., Wanner, C., Sommerer, C., Kunzendorf, U., Banas, B., Hörl, W. H., Obermüller, N., et al. (2010) · New England Journal of Medicine

Genetic and Kidney Cyst DiseasesTuberous Sclerosis Complex Research

Cited by 587

Erythropoietic response and outcomes in kidney disease and type 2 diabetes

Solomon, S. D., Uno, H., Lewis, E. F., Eckardt, K.-U., Lin, J., Burdmann, E. A., de Zeeuw, D., Ivanovich, P., Levey, A. S., Parfrey, P., et al. (2010) · New England Journal of Medicine

Erythropoietin and Anemia TreatmentBiosimilars and Bioanalytical Methods

Cited by 473

Drug dosing consideration in patients with acute and chronic kidney disease-a clinical update from Kidney Disease: Improving Global Outcomes (KDIGO)

Matzke, G. R., Aronoff, G. R., Atkinson, A. J., Bennett, W. M., Decker, B. S., Eckardt, K.-U., Golper, T., Grabe, D. W., Kasiske, B., Keller, F., et al. (2011) · Kidney International

Antibiotics Pharmacokinetics and EfficacyChronic Kidney Disease and Diabetes

Cited by 462

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

Mahajan, A., Wessel, J., Willems, S. M., Zhao, W., Robertson, N. R., Chu, A. Y., Gan, W., Kitajima, H., Taliun, D., Rayner, N. W., et al. (2018) · Nature Genetics

Genetic Associations and EpidemiologyGenomics and Rare Diseases

Cited by 442

Hypoxia and Hypoxia-Inducible Factor-1α Modulate Lipopolysaccharide-Induced Dendritic Cell Activation and Function

Jantsch, J., Chakravortty, D., Turza, N., Prechtel, A. T., Buchholz, B., Gerlach, R. G., Volke, M., Gläsner, J., Warnecke, C., Wiesener, M. S., et al. (2008) · The Journal of Immunology

Cancer, Hypoxia, and MetabolismImmunotherapy and Immune Responses

Cited by 414

Estimated Glomerular Filtration Rate, Albuminuria, and Adverse Outcomes: An Individual-Participant Data Meta-Analysis

Writing Group for the CKD Prognosis Consortium, Appel, L. J., Grams, M., Woodward, M., Harris, K., Arima, H., Chalmers, J., Yatsuya, H., Tamakoshi, K., Li, Y., et al. (2023) · JAMA

Chronic Kidney Disease and DiabetesAcute Kidney Injury Research

Cited by 396

Inhibition of Prolyl Hydroxylases Increases Erythropoietin Production in ESRD

Bernhardt, W. M., Wiesener, M. S., Scigalla, P., Chou, J., Schmieder, R. E., Günzler, V., & Eckardt, K.-U. (2010) · Journal of the American Society of Nephrology

Erythropoietin and Anemia TreatmentHemoglobin structure and function

Cited by 340

Change in albuminuria and subsequent risk of end-stage kidney disease: an individual participant-level consortium meta-analysis of observational studies

Coresh, J., Heerspink, H. J. L., Sang, Y., Matsushita, K., Arnlov, J., Astor, B. C., Black, C., Brunskill, N. J., Carrero, J.-J., Feldman, H. I., et al. (2019) · The Lancet Diabetes & Endocrinology

Chronic Kidney Disease and DiabetesAcute Kidney Injury Research

Cited by 338

Long-term space flight simulation reveals infradian rhythmicity in human Na(+) balance

Rakova, N., Jüttner, K., Dahlmann, A., Schröder, A., Linz, P., Kopp, C., Rauh, M., Goller, U., Beck, L., Agureev, A., et al. (2013) · Cell Metabolism

Sodium Intake and HealthRenin-Angiotensin System Studies

Cited by 328

Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation

Teumer, A., Chaker, L., Groeneweg, S., Li, Y., Di Munno, C., Barbieri, C., Schultheiss, U. T., Traglia, M., Ahluwalia, T. S., Akiyama, M., et al. (2018) · Nature Communications

Thyroid Disorders and TreatmentsGenetic Associations and Epidemiology

Cited by 280

A time-resolved proteomic and prognostic map of COVID-19

Demichev, V., Tober-Lau, P., Lemke, O., Nazarenko, T., Thibeault, C., Whitwell, H., Röhl, A., Freiwald, A., Szyrwiel, L., Ludwig, D., et al. (2021) · Cell Systems

COVID-19 Clinical Research StudiesSARS-CoV-2 and COVID-19 Research

Cited by 200

Agreement Between 24-Hour Salt Ingestion and Sodium Excretion in a Controlled Environment

Lerchl, K., Rakova, N., Dahlmann, A., Rauh, M., Goller, U., Basner, M., Dinges, D. F., Beck, L., Agureev, A., Larina, I., et al. (2015) · Hypertension

Sodium Intake and HealthBlood Pressure and Hypertension Studies

Cited by 198

Skin Sodium Concentration Correlates with Left Ventricular Hypertrophy in CKD

Schneider, M. P., Raff, U., Kopp, C., Scheppach, J. B., Toncar, S., Wanner, C., Schlieper, G., Saritas, T., Floege, J., Schmid, M., et al. (2017) · Journal of the American Society of Nephrology

Sodium Intake and HealthBlood Pressure and Hypertension Studies

Cited by 195

International consensus definitions of clinical trial outcomes for kidney failure: 2020

Levin, A., Agarwal, R., Herrington, W. G., Heerspink, H. L., Mann, J. F. E., Shahinfar, S., Tuttle, K. R., Donner, J.-A., Jha, V., Nangaku, M., et al. (2020) · Kidney International

Chronic Kidney Disease and DiabetesStatistical Methods in Clinical Trials

Cited by 125

Toll-like receptor activation and hypoxia use distinct signaling pathways to stabilize hypoxia-inducible factor 1α (HIF1A) and result in differential HIF1A-dependent gene expression

Jantsch, J., Wiese, M., Schödel, J., Castiglione, K., Gläsner, J., Kolbe, S., Mole, D., Schleicher, U., Eckardt, K.-U., Hensel, M., et al. (2011) · Journal of Leukocyte Biology

Cancer, Hypoxia, and MetabolismImmune Response and Inflammation

Cited by 108

Evidence for a lack of a direct transcriptional suppression of the iron regulatory peptide hepcidin by hypoxia-inducible factors

Volke, M., Gale, D. P., Maegdefrau, U., Schley, G., Klanke, B., Bosserhoff, A.-K., Maxwell, P. H., Eckardt, K.-U., & Warnecke, C. (2009) · PLoS ONE

Iron Metabolism and DisordersErythropoietin and Anemia Treatment

Cited by 93

A novel but frequent variant in LPA KIV-2 is associated with a pronounced Lp(a) and cardiovascular risk reduction

Coassin, S., Erhart, G., Weissensteiner, H., Eca Guimarães de Araújo, M., Lamina, C., Schönherr, S., Forer, L., Haun, M., Losso, J. L., Köttgen, A., et al. (2017) · European Heart Journal

Lipoproteins and Cardiovascular HealthGenetic Associations and Epidemiology

Cited by 93