Philips, Mark R.

Differential Localization of Rho Gtpases in Live Cells

Michaelson, D., Silletti, J., Murphy, G., D'Eustachio, P., Rush, M., & Philips, M. R. (2001) · The Journal of Cell Biology

Protein Kinase Regulation and GTPase SignalingCellular transport and secretion

Cited by 679

Ras signalling on the endoplasmic reticulum and the Golgi

Chiu, V. K., Bivona, T., Hach, A., Sajous, J. B., Silletti, J., Wiener, H., Johnson, R. L., Cox, A. D., & Philips, M. R. (2002) · Nature Cell Biology

Protein Kinase Regulation and GTPase SignalingCellular transport and secretion

Cited by 594

Targeting RAS Membrane Association: Back to the Future for Anti-RAS Drug Discovery?

Cox, A. D., Der, C. J., & Philips, M. R. (2015) · Clinical Cancer Research

Protein Kinase Regulation and GTPase SignalingProtein Tyrosine Phosphatases

Cited by 351

Receptor Activation Alters Inner Surface Potential During Phagocytosis

Yeung, T., Terebiznik, M., Yu, L., Silvius, J., Abidi, W. M., Philips, M., Levine, T., Kapus, A., & Grinstein, S. (2006) · Science

Lipid Membrane Structure and BehaviorCellular transport and secretion

Cited by 329

KRAS4A directly regulates hexokinase 1

Amendola, C. R., Mahaffey, J. P., Parker, S. J., Ahearn, I. M., Chen, W.-C., Zhou, M., Court, H., Shi, J., Mendoza, S. L., Morten, M. J., et al. (2019) · Nature

Cancer, Hypoxia, and MetabolismProtein Kinase Regulation and GTPase Signaling

Cited by 203

Selective alanine transporter utilization creates a targetable metabolic niche in pancreatic cancer

Parker, S. J., Amendola, C. R., Hollinshead, K. E. R., Yu, Q., Yamamoto, K., Encarnación-Rosado, J., Rose, R. E., LaRue, M. M., Sohn, A. S. W., Biancur, D. E., et al. (2020) · Cancer Discovery

Amino Acid Enzymes and MetabolismPancreatic and Hepatic Oncology Research

Cited by 175

ULK1 inhibition overcomes compromised antigen presentation and restores antitumor immunity in LKB1-mutant lung cancer

Deng, J., Thennavan, A., Dolgalev, I., Chen, T., Li, J., Marzio, A., Poirier, J. T., Peng, D. H., Bulatovic, M., Mukhopadhyay, S., et al. (2021) · Nature Cancer

Cancer Immunotherapy and BiomarkersAutophagy in Disease and Therapy

Cited by 140

Proteasomal adaptation to environmental stress links resistance to proteotoxicity with longevity in Caenorhabditis elegans

Yun, C., Stanhill, A., Yang, Y., Zhang, Y., Haynes, C. M., Xu, C.-F., Neubert, T. A., Mor, A., Philips, M. R., & Ron, D. (2008) · Proceedings of the National Academy of Sciences

Genetics, Aging, and Longevity in Model OrganismsUbiquitin and proteasome pathways

Cited by 98

K-Ras Lys-42 is crucial for its signaling, cell migration, and invasion

Choi, B. H., Philips, M. R., Chen, Y., Lu, L., & Dai, W. (2018) · Journal of Biological Chemistry

Protein Kinase Regulation and GTPase SignalingUbiquitin and proteasome pathways

Cited by 42

RAS GTPases are modified by SUMOylation

Choi, B. H., Chen, C., Philips, M., & Dai, W. (2018) · Oncotarget

Ubiquitin and proteasome pathwaysProtein Kinase Regulation and GTPase Signaling

Cited by 32