Backos, Donald S.

Lysine glutarylation is a protein posttranslational modification regulated by SIRT5

Tan, M., Peng, C., Anderson, K. A., Chhoy, P., Xie, Z., Dai, L., Park, J., Chen, Y., Huang, H., Zhang, Y., et al. (2014) · Cell Metabolism

Sirtuins and Resveratrol in MedicineCancer-related gene regulation

Cited by 844

Complement proteins bind to nanoparticle protein corona and undergo dynamic exchange in vivo

Chen, F., Wang, G., Griffin, J. I., Brenneman, B., Banda, N. K., Holers, V. M., Backos, D. S., Wu, L., Moghimi, S. M., & Simberg, D. (2017) · Nature Nanotechnology

Nanoparticle-Based Drug DeliveryComplement system in diseases

Cited by 599

Structure, function, and post–translational regulation of the catalytic and modifier subunits of glutamate cysteine ligase

Franklin, C. C., Backos, D. S., Mohar, I., White, C. C., Forman, H. J., & Kavanagh, T. J. (2009) · Molecular Aspects of Medicine

Sulfur Compounds in BiologyGlutathione Transferases and Polymorphisms

Cited by 438

SIRT4 is a lysine deacylase that controls leucine metabolism and insulin secretion

Anderson, K. A., Huynh, F. K., Fisher-Wellman, K., Stuart, J. D., Peterson, B. S., Douros, J. D., Wagner, G. R., Thompson, J. W., Madsen, A. S., Green, M. F., et al. (2017) · Cell Metabolism

Sirtuins and Resveratrol in MedicineAutophagy in Disease and Therapy

Cited by 326

A Class of Reactive Acyl-CoA Species Reveals the Non-enzymatic Origins of Protein Acylation

Wagner, G. R., Bhatt, D. P., O’Connell, T. M., Thompson, J. W., Dubois, L. G., Backos, D. S., Yang, H., Mitchell, G. A., Ilkayeva, O. R., Stevens, R. D., et al. (2017) · Cell Metabolism

Cancer, Lipids, and MetabolismAdvanced Proteomics Techniques and Applications

Cited by 258

Brain-derived Neurotrophic Factor Regulates the Expression and Synaptic Delivery ofα-Amino-3-hydroxy-5-methyl-4-isoxazole Propionic Acid Receptor Subunits in Hippocampal Neurons

Caldeira, M. V., Melo, C. V., Pereira, D. B., Carvalho, R., Correia, S. S., Backos, D. S., Carvalho, A. L., Esteban, J. A., & Duarte, C. B. (2007) · Journal of Biological Chemistry

Neuroscience and Neuropharmacology ResearchNerve injury and regeneration

Cited by 251

Dual role of the exocyst in AMPA receptor targeting and insertion into the postsynaptic membrane

Gerges, N. Z., Backos, D. S., Rupasinghe, C. N., Spaller, M. R., & Esteban, J. A. (2006) · The EMBO Journal

Neuroscience and Neuropharmacology ResearchCellular transport and secretion

Cited by 147

Increased carbonylation of the lipid phosphatase PTEN contributes to Akt2 activation in a murine model of early alcohol-induced steatosis

Shearn, C. T., Smathers, R. L., Backos, D. S., Reigan, P., Orlicky, D. J., & Petersen, D. R. (2013) · Free Radical Biology and Medicine

Alcohol Consumption and Health EffectsLiver Disease Diagnosis and Treatment

Cited by 69

Identification of 5′ AMP-activated Kinase as a Target of Reactive Aldehydes during Chronic Ingestion of High Concentrations of Ethanol

Shearn, C. T., Backos, D. S., Orlicky, D. J., Smathers-McCullough, R. L., & Petersen, D. R. (2014) · Journal of Biological Chemistry

Alcohol Consumption and Health EffectsMetabolism, Diabetes, and Cancer

Cited by 57

Oxidative stress-mediated aldehyde adduction of GRP78 in a mouse model of alcoholic liver disease: functional independence of ATPase activity and chaperone function

Galligan, J. J., Fritz, K. S., Backos, D. S., Shearn, C. T., Smathers, R. L., Jiang, H., MacLean, K. N., Reigan, P. R., & Petersen, D. R. (2014) · Free Radical Biology and Medicine

Endoplasmic Reticulum Stress and DiseaseHeat shock proteins research

Cited by 46

4-Hydroxy-2-nonenal attenuates 8-oxoguanine DNA glycosylase 1 activity

Pan, G., Deshpande, M., Pang, H., Stemmer, P. M., Carruthers, N. J., Shearn, C. T., Backos, D. S., & Palaniyandi, S. S. (2020) · Journal of Cellular Biochemistry

DNA Repair MechanismsRedox biology and oxidative stress

Cited by 16