Murakami, Masaaki

COVID-19: a new virus, but a familiar receptor and cytokine release syndrome

Hirano, T., & Murakami, M. (2020) · Immunity

SARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research Studies

Cited by 772

IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages

Yasukawa, H., Ohishi, M., Mori, H., Murakami, M., Chinen, T., Aki, D., Hanada, T., Takeda, K., Akira, S., Hoshijima, M., et al. (2003) · Nature Immunology

Cytokine Signaling Pathways and InteractionsAdipokines, Inflammation, and Metabolic Diseases

Cited by 771

How COVID-19 induces cytokine storm with high mortality

Hojyo, S., Uchida, M., Tanaka, K., Hasebe, R., Tanaka, Y., Murakami, M., & Hirano, T. (2020) · Inflammation and Regeneration

COVID-19 Clinical Research StudiesCytokine Signaling Pathways and Interactions

Cited by 663

Interleukin-17 promotes autoimmunity by triggering a positive-feedback loop via interleukin-6 induction

Ogura, H., Murakami, M., Okuyama, Y., Tsuruoka, M., Kitabayashi, C., Kanamoto, M., Nishihara, M., Iwakura, Y., & Hirano, T. (2008) · Immunity

Psoriasis: Treatment and PathogenesisCytokine Signaling Pathways and Interactions

Cited by 564

Pleiotropy and specificity: insights from the interleukin 6 family of cytokines

Murakami, M., Kamimura, D., & Hirano, T. (2019) · Immunity

Cytokine Signaling Pathways and InteractionsPsoriasis: Treatment and Pathogenesis

Cited by 533

IL-6 regulates in vivo dendritic cell differentiation through STAT3 activation

Park, S.-J., Nakagawa, T., Kitamura, H., Atsumi, T., Kamon, H., Sawa, S.-I., Kamimura, D., Ueda, N., Iwakura, Y., Ishihara, K., et al. (2004) · The Journal of Immunology

Cytokine Signaling Pathways and InteractionsImmunotherapy and Immune Responses

Cited by 519

Regional neural activation defines a gateway for autoreactive T cells to cross the blood-brain barrier

Arima, Y., Harada, M., Kamimura, D., Park, J.-H., Kawano, F., Yull, F. E., Kawamoto, T., Iwakura, Y., Betz, U. A. K., Márquez, G., et al. (2012) · Cell

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 307

IL-6-gp130-STAT3 in T cells directs the development of IL-17+ Th with a minimum effect on that of Treg in the steady state

Nishihara, M., Ogura, H., Ueda, N., Tsuruoka, M., Kitabayashi, C., Tsuji, F., Aono, H., Ishihara, K., Huseby, E., Betz, U. A. K., et al. (2007) · International Immunology

Psoriasis: Treatment and PathogenesisCytokine Signaling Pathways and Interactions

Cited by 268

IL-6-STAT3 Controls Intracellular MHC Class II αβ Dimer Level through Cathepsin S Activity in Dendritic Cells

Kitamura, H., Kamon, H., Sawa, S.-I., Park, S.-J., Katunuma, N., Ishihara, K., Murakami, M., & Hirano, T. (2005) · Immunity

Cytokine Signaling Pathways and InteractionsImmunotherapy and Immune Responses

Cited by 223

Inflammation amplifier, a new paradigm in cancer biology

Atsumi, T., Singh, R., Sabharwal, L., Bando, H., Meng, J., Arima, Y., Yamada, M., Harada, M., Jiang, J.-J., Kamimura, D., et al. (2014) · Cancer Research

Cytokine Signaling Pathways and InteractionsNF-κB Signaling Pathways

Cited by 217

Autoimmune arthritis associated with mutated interleukin (IL)-6 receptor gp130 is driven by STAT3/IL-7-dependent homeostatic proliferation of CD4+ T cells

Sawa, S.-I., Kamimura, D., Jin, G.-H., Morikawa, H., Kamon, H., Nishihara, M., Ishihara, K., Murakami, M., & Hirano, T. (2006) · The Journal of Experimental Medicine

Cytokine Signaling Pathways and InteractionsRheumatoid Arthritis Research and Therapies

Cited by 176

ARF6 and AMAP1 are major targets of KRAS and TP53 mutations to promote invasion, PD-L1 dynamics, and immune evasion of pancreatic cancer

Hashimoto, S., Furukawa, S., Hashimoto, A., Tsutaho, A., Fukao, A., Sakamura, Y., Parajuli, G., Onodera, Y., Otsuka, Y., Handa, H., et al. (2019) · Proceedings of the National Academy of Sciences

Pancreatic and Hepatic Oncology ResearchProtein Kinase Regulation and GTPase Signaling

Cited by 149

Disease-association analysis of an inflammation-related feedback loop

Murakami, M., Harada, M., Kamimura, D., Ogura, H., Okuyama, Y., Kumai, N., Okuyama, A., Singh, R., Jiang, J.-J., Atsumi, T., et al. (2013) · Cell Reports

NF-κB Signaling PathwaysCytokine Signaling Pathways and Interactions

Cited by 110

Local microbleeding facilitates IL-6- and IL-17-dependent arthritis in the absence of tissue antigen recognition by activated T cells

Murakami, M., Okuyama, Y., Ogura, H., Asano, S., Arima, Y., Tsuruoka, M., Harada, M., Kanamoto, M., Sawa, Y., Iwakura, Y., et al. (2011) · Journal of Experimental Medicine

Rheumatoid Arthritis Research and TherapiesT-cell and B-cell Immunology

Cited by 100

Ecto-nucleoside triphosphate diphosphohydrolase 7 controls Th17 cell responses through regulation of luminal ATP in the small intestine

Kusu, T., Kayama, H., Kinoshita, M., Jeon, S. G., Ueda, Y., Goto, Y., Okumura, R., Saiga, H., Kurakawa, T., Ikeda, K., et al. (2013) · The Journal of Immunology

Adenosine and Purinergic SignalingBiochemical and Molecular Research

Cited by 73

A pain-mediated neural signal induces relapse in murine autoimmune encephalomyelitis, a multiple sclerosis model

Arima, Y., Kamimura, D., Atsumi, T., Harada, M., Kawamoto, T., Nishikawa, N., Stofkova, A., Ohki, T., Higuchi, K., Morimoto, Y., et al. (2015) · eLife

Multiple Sclerosis Research StudiesPain Mechanisms and Treatments

Cited by 66

A four-step model for the IL-6 amplifier, a regulator of chronic inflammations in tissue-specific MHC class II-associated autoimmune diseases

Murakami, M., & Hirano, T. (2011) · Frontiers in Immunology

Rheumatoid Arthritis Research and TherapiesCytokine Signaling Pathways and Interactions

Cited by 53

Mast cells play role in wound healing through the ZnT2/GPR39/IL-6 axis

Nishida, K., Hasegawa, A., Yamasaki, S., Uchida, R., Ohashi, W., Kurashima, Y., Kunisawa, J., Kimura, S., Iwanaga, T., Watarai, H., et al. (2019) · Scientific Reports

Wound Healing and TreatmentsTrace Elements in Health

Cited by 53

Gateway reflex: neural activation-mediated immune cell gateways in the central nervous system

Kamimura, D., Ohki, T., Arima, Y., & Murakami, M. (2018) · International Immunology

Vagus Nerve Stimulation ResearchNeuroinflammation and Neurodegeneration Mechanisms

Cited by 12