Keating, Amy E.

Comprehensive Identification of Human bZIP Interactions with Coiled-Coil Arrays

Newman, J. R. S., & Keating, A. E. (2003) · Science

Genomics and Chromatin DynamicsProtein Structure and Dynamics

Cited by 449

Paircoil2: improved prediction of coiled coils from sequence.

McDonnell, A. V., Jiang, T., Keating, A. E., & Berger, B. (2006) · Bioinformatics

Protein Structure and DynamicsMachine Learning in Bioinformatics

Cited by 424

The MCL-1 BH3 helix is an exclusive MCL-1 inhibitor and apoptosis sensitizer

Stewart, M. L., Fire, E., Keating, A. E., & Walensky, L. D. (2010) · Nature Chemical Biology

Cell death mechanisms and regulationChemical Synthesis and Analysis

Cited by 418

AB ‐Bind: Antibody binding mutational database for computational affinity predictions

Sirin, S., Apgar, J. R., Bennett, E. M., & Keating, A. E. (2016) · Protein Science

Protein Structure and DynamicsMonoclonal and Polyclonal Antibodies Research

Cited by 179

Multicoil2: Predicting Coiled Coils and Their Oligomerization States from Sequence in the Twilight Zone

Trigg, J., Gutwin, K., Keating, A. E., & Berger, B. (2011) · PLoS One

Protein Structure and DynamicsMachine Learning in Bioinformatics

Cited by 91

Genome-wide prediction and validation of peptides that bind human prosurvival Bcl-2 proteins

DeBartolo, J., Taipale, M., & Keating, A. E. (2014) · PLoS Computational Biology

Cell death mechanisms and regulationComputational Drug Discovery Methods

Cited by 39

Neural Network-Derived Potts Models for Structure-Based Protein Design using Backbone Atomic Coordinates and Tertiary Motifs

Li, A. J., Lu, M., Desta, I., Sundar, V., Grigoryan, G., & Keating, A. E. (2022) · Protein Science

Protein Structure and DynamicsMachine Learning in Bioinformatics

Cited by 25

High-throughput discovery of inhibitory protein fragments with AlphaFold

Savinov, A., Swanson, S., Keating, A. E., & Li, G.-W. (2023) · Proceedings of the National Academy of Sciences

Protein Structure and DynamicsComputational Drug Discovery Methods

Cited by 18

High-throughput discovery of inhibitory protein fragments with AlphaFold

Savinov, A., Swanson, S., Keating, A. E., & Li, G.-W. (2025) · Proceedings of the National Academy of Sciences

Protein Structure and DynamicsComputational Drug Discovery Methods

Cited by 18

Molecular determinants of TRAF6 binding specificity suggest that native interaction partners are not optimized for affinity

Halpin, J. C., Whitney, D., Rigoldi, F., Sivaraman, V., Singer, A., & Keating, A. E. (2022) · Protein Science

NF-κB Signaling PathwaysChemical Synthesis and Analysis

Cited by 7

Molecular determinants of TRAF6 binding specificity suggest that native interaction partners are not optimized for affinity

Halpin, J. C., Whitney, D., Rigoldi, F., Sivaraman, V., Singer, A., & Keating, A. E. (2022) · Protein Science

NF-κB Signaling PathwaysChemical Synthesis and Analysis

Cited by 7

Elaboration of the Homer1 Recognition Landscape Reveals Incomplete Divergence of Paralogous EVH1 Domains

Singer, A., Ramos, A., & Keating, A. E. (2024) · Protein Science

Protein Structure and DynamicsGenomics and Chromatin Dynamics

Cited by 6

Elaboration of the Homer1 recognition landscape reveals incomplete divergence of paralogous EVH1 domains

Singer, A., Ramos, A., & Keating, A. E. (2024) · Protein Science

Protein Structure and DynamicsGenomics and Chromatin Dynamics

Cited by 6