Manfredi, Giovanni

Proteolytic Cleavage of Opa1 Stimulates Mitochondrial Inner Membrane Fusion and Couples Fusion to Oxidative Phosphorylation

Mishra, P., Carelli, V., Manfredi, G., & Chan, D. C. (2014) · Cell Metabolism

Mitochondrial Function and PathologyAutophagy in Disease and Therapy

Cited by 473

IRE1α–XBP1 controls T cell function in ovarian cancer by regulating mitochondrial activity

Song, M., Sandoval, T. A., Chae, C.-S., Chopra, S., Tan, C., Rutkowski, M. R., Raundhal, M., Chaurio, R. A., Payne, K. K., Konrad, C., et al. (2018) · Nature

Endoplasmic Reticulum Stress and DiseaseCancer Immunotherapy and Biomarkers

Cited by 413

The Role of Memantine in the Treatment of Psychiatric Disorders Other Than the Dementias: A Review of Current Preclinical and Clinical Evidence

Sani, G., Serra, G., Kotzalidis, G. D., Romano, S., Tamorri, S. M., Manfredi, G., Caloro, M., Telesforo, C. L., Caltagirone, S. S., Panaccione, I., et al. (2012) · CNS Drugs

Treatment of Major DepressionSchizophrenia research and treatment

Cited by 273

Protein Phosphorylation and Prevention of Cytochrome Oxidase Inhibition by ATP: Coupled Mechanisms of Energy Metabolism Regulation

Acin-Perez, R., Gatti, D. L., Bai, Y., & Manfredi, G. (2011) · Cell Metabolism

Mitochondrial Function and PathologyATP Synthase and ATPases Research

Cited by 190

Pink1 regulates the oxidative phosphorylation machinery via mitochondrial fission

Liu, W., Acín-Peréz, R., Geghman, K. D., Manfredi, G., Lu, B., & Li, C. (2011) · Proceedings of the National Academy of Sciences

Mitochondrial Function and PathologyParkinson's Disease Mechanisms and Treatments

Cited by 190

The role of mitochondria in inherited neurodegenerative diseases

Kwong, J. Q., Beal, M. F., & Manfredi, G. (2006) · Journal of Neurochemistry

Mitochondrial Function and PathologyHereditary Neurological Disorders

Cited by 180

Cell‐permeable peptide antioxidants as a novel therapeutic approach in a mouse model of amyotrophic lateral sclerosis

Petri, S., Kiaei, M., Damiano, M., Hiller, A., Wille, E., Manfredi, G., Calingasan, N. Y., Szeto, H. H., & Beal, M. F. (2006) · Journal of Neurochemistry

Amyotrophic Lateral Sclerosis ResearchAlzheimer's disease research and treatments

Cited by 166

SOD1, an unexpected novel target for cancer therapy.

Papa, L., Manfredi, G., & Germain, D. (2014) · Genes & Cancer

Redox biology and oxidative stressCancer and biochemical research

Cited by 147

Suicide in a large population of former psychiatric inpatients

Sani, G., Tondo, L., Koukopoulos, A., Reginaldi, D., Kotzalidis, G. D., Koukopoulos, A. E., Manfredi, G., Mazzarini, L., Pacchiarotti, I., Simonetti, A., et al. (2011) · Psychiatry and Clinical Neurosciences

Suicide and Self-Harm StudiesBipolar Disorder and Treatment

Cited by 119

Energy deficit in parvalbumin neurons leads to circuit dysfunction, impaired sensory gating and social disability.

Inan, M., Zhao, M., Manuszak, M., Karakaya, C., Rajadhyaksha, A. M., Pickel, V. M., Schwartz, T. H., Goldstein, P. A., & Manfredi, G. (2016) · Neurobiology of Disease

Mitochondrial Function and PathologyNeuroscience and Neuropharmacology Research

Cited by 118

Abnormal Intracellular Calcium Signaling and SNARE-Dependent Exocytosis Contributes to SOD1G93A Astrocyte-Mediated Toxicity in Amyotrophic Lateral Sclerosis

Kawamata, H., Ng, S. K., Diaz, N., Burstein, S., Morel, L., Osgood, A., Sider, B., Higashimori, H., Haydon, P. G., Manfredi, G., et al. (2014) · The Journal of Neuroscience

Amyotrophic Lateral Sclerosis ResearchCellular transport and secretion

Cited by 97

Muscle choline kinase beta defect causes mitochondrial dysfunction and increased mitophagy

Mitsuhashi, S., Hatakeyama, H., Karahashi, M., Koumura, T., Nonaka, I., Hayashi, Y. K., Noguchi, S., Sher, R. B., Nakagawa, Y., Manfredi, G., et al. (2011) · Human Molecular Genetics

Mitochondrial Function and PathologyMuscle Physiology and Disorders

Cited by 95

Functional neuroimaging in specific phobia

Del Casale, A., Ferracuti, S., Rapinesi, C., Serata, D., Piccirilli, M., Savoja, V., Kotzalidis, G. D., Manfredi, G., Angeletti, G., Tatarelli, R., et al. (2012) · Psychiatry Research: Neuroimaging

Anxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesMemory and Neural Mechanisms

Cited by 90

Control of oxidative phosphorylation by vitamin A illuminates a fundamental role in mitochondrial energy homoeostasis

Acin‐Perez, R., Hoyos, B., Zhao, F., Vinogradov, V., Fischman, D. A., Harris, R. A., Leitges, M., Wongsiriroj, N., Blaner, W. S., Manfredi, G., et al. (2010) · The FASEB Journal

Mitochondrial Function and PathologyRetinoids in leukemia and cellular processes

Cited by 81

The mitochondrial calcium regulator cyclophilin d is an essential component of oestrogen-mediated neuroprotection in amyotrophic lateral sclerosis

Kim, H. J., Magranè, J., Starkov, A. A., & Manfredi, G. (2012) · Brain

Amyotrophic Lateral Sclerosis ResearchMitochondrial Function and Pathology

Cited by 64

Effectiveness of Short-Term Olanzapine in Patients With Bipolar I Disorder, With or Without Comorbidity With Substance Use Disorder

Sani, G., Kotzalidis, G. D., Vöhringer, P., Pucci, D., Simonetti, A., Manfredi, G., Savoja, V., Tamorri, S. M., Mazzarini, L., Pacchiarotti, I., et al. (2013) · Journal of Clinical Psychopharmacology

Bipolar Disorder and TreatmentSchizophrenia research and treatment

Cited by 27