Hiebert, Scott W.

AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis.

Okuda, T., van Deursen, J., Hiebert, S. W., Grosveld, G., & Downing, J. R. (1996) · Cell

Acute Myeloid Leukemia ResearchHematopoietic Stem Cell Transplantation

Cited by 1,856

Direct binding of cyclin D to the retinoblastoma gene product (pRb) and pRb phosphorylation by the cyclin D-dependent kinase CDK4

Kato, J., Matsushime, H., Hiebert, S. W., Ewen, M. E., & Sherr, C. J. (1993) · Genes & Development

Cancer-related Molecular PathwaysProtein Kinase Regulation and GTPase Signaling

Cited by 1,264

Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia.

Golub, T. R., Barker, G. F., Bohlander, S. K., Hiebert, S. W., Ward, D. C., Bray-Ward, P., Morgan, E., Raimondi, S. C., Rowley, J. D., & Gilliland, D. G. (1995) · Proceedings of the National Academy of Sciences

Acute Lymphoblastic Leukemia researchAcute Myeloid Leukemia Research

Cited by 704

Requirement for the histone deacetylase Hdac3 for the inflammatory gene expression program in macrophages

Chen, X., Barozzi, I., Termanini, A., Prosperini, E., Recchiuti, A., Dalli, J., Mietton, F., Matteoli, G., Hiebert, S., & Natoli, G. (2012) · Proceedings of the National Academy of Sciences

Histone Deacetylase Inhibitors ResearchGenomics and Chromatin Dynamics

Cited by 397

CCAAT Enhancer-Binding Protein (C/EBP) and AML1 (CBFα2) Synergistically Activate the Macrophage Colony-Stimulating Factor Receptor Promoter

Zhang, D.-E., Hetherington, C. J., Meyers, S., Rhoades, K. L., Larson, C. J., Chen, H.-M., Hiebert, S. W., & Tenen, D. G. (1996) · Molecular and Cellular Biology

Genomics and Chromatin DynamicsAcute Myeloid Leukemia Research

Cited by 396

The t(8;21) Fusion Protein Interferes with AML-1B-Dependent Transcriptional Activation

Meyers, S., Lenny, N., & Hiebert, S. W. (1995) · Molecular and Cellular Biology

Acute Myeloid Leukemia ResearchRetinoids in leukemia and cellular processes

Cited by 368

Hdac3 is essential for the maintenance of chromatin structure and genome stability

Bhaskara, S., Knutson, S. K., Jiang, G., Chandrasekharan, M. B., Wilson, A. J., Zheng, S., Yenamandra, A., Locke, K., Yuan, J.-L., Bonine-Summers, A. R., et al. (2010) · Cancer Cell

Histone Deacetylase Inhibitors ResearchGenomics and Chromatin Dynamics

Cited by 353

PEBP2/CBF, the murine homolog of the human myeloid AML1 and PEBP2 beta/CBF beta proto-oncoproteins, regulates the murine myeloperoxidase and neutrophil elastase genes in immature myeloid cells.

Nuchprayoon, I., Meyers, S., Scott, L. M., Suzow, J., Hiebert, S., & Friedman, A. D. (1994) · Molecular and Cellular Biology

Genomics and Chromatin DynamicsAcute Myeloid Leukemia Research

Cited by 296

CREBBP Inactivation Promotes the Development of HDAC3-Dependent Lymphomas

Jiang, Y., Ortega-Molina, A., Geng, H., Ying, H.-Y., Hatzi, K., Parsa, S., McNally, D., Wang, L., Doane, A. S., Agirre, X., et al. (2017) · Cancer Discovery

Lymphoma Diagnosis and TreatmentGenomics and Chromatin Dynamics

Cited by 278

The t(12;21) Translocation Converts AML-1B from an Activator to a Repressor of Transcription

Hiebert, S. W., Sun, W., Nathan Davis, J., Golub, T., Shurtleff, S., Buijs, A., Downing, J. R., Grosveld, G., Roussel, M. F., Gary Gilliland, D., et al. (1996) · Molecular and Cellular Biology

Acute Lymphoblastic Leukemia researchGenomics and Chromatin Dynamics

Cited by 272

Liver-specific deletion of histone deacetylase 3 disrupts metabolic transcriptional networks

Knutson, S. K., Chyla, B. J., Amann, J. M., Bhaskara, S., Huppert, S. S., & Hiebert, S. W. (2008) · The EMBO Journal

Histone Deacetylase Inhibitors ResearchPeroxisome Proliferator-Activated Receptors

Cited by 271

The t(8;21) Fusion Product, AML-1–ETO, Associates with C/EBP-α, Inhibits C/EBP-α-Dependent Transcription, and Blocks Granulocytic Differentiation

Westendorf, J. J., Yamamoto, C. M., Lenny, N., Downing, J. R., Selsted, M. E., & Hiebert, S. W. (1998) · Molecular and Cellular Biology

Acute Myeloid Leukemia ResearchRetinoids in leukemia and cellular processes

Cited by 270

Multiple Functional Domains of AML1: PU.1 and C/EBPα Synergize with Different Regions of AML1

Petrovick, M. S., Hiebert, S. W., Friedman, A. D., Hetherington, C. J., Tenen, D. G., & Zhang, D.-E. (1998) · Molecular and Cellular Biology

Genomics and Chromatin DynamicsAcute Myeloid Leukemia Research

Cited by 223

Both TEL and AML-1 Contribute Repression Domains to the t(12;21) Fusion Protein

Fenrick, R., Amann, J. M., Lutterbach, B., Wang, L., Westendorf, J. J., Downing, J. R., & Hiebert, S. W. (1999) · Molecular and Cellular Biology

Acute Lymphoblastic Leukemia researchGenomics and Chromatin Dynamics

Cited by 162

The inv(16) fusion protein associates with corepressors via a smooth muscle myosin heavy-chain domain

Durst, K. L., Lutterbach, B., Kummalue, T., Friedman, A. D., & Hiebert, S. W. (2003) · Molecular and Cellular Biology

Acute Myeloid Leukemia ResearchGenomics and Chromatin Dynamics

Cited by 161

Synergistic up-regulation of the myeloid-specific promoter for the macrophage colony-stimulating factor receptor by AML1 and the t(8;21) fusion protein may contribute to leukemogenesis.

Rhoades, K. L., Hetherington, C. J., Rowley, J. D., Hiebert, S. W., Nucifora, G., Tenen, D. G., & Zhang, D. E. (1996) · Proceedings of the National Academy of Sciences

Acute Myeloid Leukemia ResearchRetinoids in leukemia and cellular processes

Cited by 129

TEL contacts multiple co-repressors and specifically associates with histone deacetylase-3

Wang, L., & Hiebert, S. W. (2001) · Oncogene

Genomics and Chromatin DynamicsHistone Deacetylase Inhibitors Research

Cited by 101

HDAC3 is essential for DNA replication in hematopoietic progenitor cells

Summers, A. R., Fischer, M. A., Stengel, K. R., Zhao, Y., Kaiser, J. F., Wells, C. E., Hunt, A., Bhaskara, S., Luzwick, J. W., Sampathi, S., et al. (2013) · Journal of Clinical Investigation

Hematopoietic Stem Cell TransplantationHistone Deacetylase Inhibitors Research

Cited by 87

Indirect and Direct Disruption of Transcriptional Regulation in Cancer: E2F and AML-1

Meyers, S., & Hiebert, S. W. (1995) · Critical Reviews™ in Eukaryotic Gene Expression

Cancer-related Molecular PathwaysGenomics and Chromatin Dynamics

Cited by 57