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Cloning and Characterization of Subunits of the T-Cell Receptor and Murine Leukemia Virus Enhancer Core-Binding Factor

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The macrophage transcription factor PU.1 directs tissue-specific expression of the macrophage colony-stimulating factor receptor.

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The macrophage transcription factor PU.1 directs tissue-specific expression of the macrophage colony-stimulating factor receptor

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A novel temporal expression pattern of three C/EBP family members in differentiating myelomonocytic cells

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Lymphoproliferative disorder and imbalanced T-helper response in C/EBP beta-deficient mice

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The t(8;21) Fusion Protein Interferes with AML-1B-Dependent Transcriptional Activation

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Colony-stimulating factor-1 receptor

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The runt domain identifies a new family of heterometric transcriptional regulators

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AML1 and the 8;21 and 3;21 translocations in acute and chronic myeloid leukemia

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Generation of the AML1‐EVI‐1 fusion gene in the t(3;21)(q26;q22) causes blastic crisis in chronic myelocytic leukemia.

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The activation domain of transcription factor PU.1 binds the retinoblastoma (RB) protein and the transcription factor TFIID in vitro: RB shows sequence similarity to TFIID and TFIIB.

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The Drosophila segmentation gene runt encodes a novel nuclear regulatory protein that is also expressed in the developing nervous system.Preprint

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PU.1 (Spi-1) and C/EBPα Regulate Expression of the Granulocyte-Macrophage Colony-Stimulating Factor Receptor α Gene

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Isolation of PEBP2 alpha B cDNA representing the mouse homolog of human acute myeloid leukemia gene, AML1.

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An acute myeloid leukemia gene, AML1, regulates hemopoietic myeloid cell differentiation and transcriptional activation antagonistically by two alternative spliced forms.

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CRP2 (C/EBP beta) contains a bipartite regulatory domain that controls transcriptional activation, DNA binding and cell specificity.

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Identification of a Region Which Directs the Monocytic Activity of the Colony-Stimulating Factor 1 (Macrophage Colony-Stimulating Factor) Receptor Promoter and Binds PEBP2/CBF (AML1)

Zhang, D.-E., Fujioka, K.-I., Hetherington, C. J., Shapiro, L. H., Chen, H.-M., Look, A. T., & Tenen, D. G. (1994) · Molecular and Cellular Biology · doi:10.1128/mcb.14.12.8085-8095.1994 · Cited by 199 · see citing works

Synergistic activation of the chicken mim‐1 gene by v‐myb and C/EBP transcription factors.

Burk, O., Mink, S., Ringwald, M., & Klempnauer, K.-H. (1993) · The EMBO Journal · doi:10.1002/j.1460-2075.1993.tb05852.x · Cited by 190 · see citing works

The NF‐M transcription factor is related to C/EBP beta and plays a role in signal transduction, differentiation and leukemogenesis of avian myelomonocytic cells.

Katz, S., Kowenz‐Leutz, E., Müller, C., Meese, K., Ness, S. A., & Leutz, A. (1993) · The EMBO Journal · doi:10.1002/j.1460-2075.1993.tb05777.x · Cited by 183 · see citing works

C/EBP beta regulation of the tumor necrosis factor alpha gene.

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The 3;21 translocation in myelodysplasia results in a fusion transcript between the AML1 gene and the gene for EAP, a highly conserved protein associated with the Epstein-Barr virus small RNA EBER 1.

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Cloning, mapping and expression of PEBP2αC, a third gene encoding the mammalian Runt domain

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Expression of the Runt Domain-Encoding PEBP2 α Genes in T cells during Thymic Development

Satake, M., Nomura, S., Yamaguchi‐Iwai, Y., Takahama, Y., Hashimoto, Y., Niki, M., Kitamura, Y., & Ito, Y. (1995) · Molecular and Cellular Biology · doi:10.1128/mcb.15.3.1662 · Cited by 157 · see citing works

Regulation of the T-cell receptor delta enhancer by functional cooperation between c-Myb and core-binding factors.

Hernández-Munaín, C., & Krangel, M. S. (1994) · Molecular and Cellular Biology · doi:10.1128/mcb.14.1.473 · Cited by 153 · see citing works

Positive and negative regulation of granulocyte-macrophage colony- stimulating factor promoter activity by AML1-related transcription factor, PEBP2

Takahashi, A., Satake, M., Yamaguchi‐Iwai, Y., Bae, S., Lu, J., Maruyama, M., Yw, Z., Oka, H., Arai, N., & Arai, K. (1995) · Blood · doi:10.1182/blood.v86.2.607.bloodjournal862607 · Cited by 152 · see citing works

Transcription factors NF-IL6 and CREB recognize a common essential site in the human prointerleukin 1 beta gene.

Tsukada, J., Saito, K., Waterman, W. R., Webb, A. C., & Auron, P. E. (1994) · Molecular and Cellular Biology · doi:10.1128/mcb.14.11.7285 · Cited by 149 · see citing works

Transactivation of the Moloney murine leukemia virus and T-cell receptor beta-chain enhancers by cbf and ets requires intact binding sites for both proteins

Sun, W., Graves, B. J., & Speck, N. A. (1995) · Journal of Virology · doi:10.1128/jvi.69.8.4941-4949.1995 · Cited by 148 · see citing works

Autoregulation of the Human C/EBPα Gene by Stimulation of Upstream Stimulatory Factor Binding

Timchenko, N. A., Wilson, D. R., Taylor, L. R., Abdelsayed, S. V., Wilde, M., Sawadogo, M., & Darlington, G. (1995) · Molecular and Cellular Biology · doi:10.1128/mcb.15.3.1192 · Cited by 147 · see citing works

Inhibition of hematopoiesis by competitive binding of transcription factor PU.1

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Three levels of functional interaction determine the activity of CCAAT/enhancer binding protein-alpha on the serum albumin promoter.Preprint

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Restriction of interferon gamma responsiveness and basal expression of the myeloid human Fc gamma R1b gene is mediated by a functional PU.1 site and a transcription initiator consensus.

Eichbaum, Q. G., Iyer, R., Raveh, D., Mathieu, C., & Ezekowitz, R. A. B. (1994) · The Journal of Experimental Medicine · doi:10.1084/jem.179.6.1985 · Cited by 119 · see citing works

Functional domains of the t(8;21) fusion protein, AML-1/ETO.

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Optimization of transient transfection into human myeloid cell lines using a luciferase reporter gene.

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Autocrine growth induced by kinase type oncogenes in myeloid cells requires AP‐1 and NF‐M, a myeloid specific, C/EBP‐like factor.

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Differential Transcription of Exon 1 of the Human c-fms Gene in Placental Trophoblasts and Monocytes

Visvader, J. E., & Verma, I. M. (1989) · Molecular and Cellular Biology · doi:10.1128/mcb.9.3.1336 · Cited by 87 · see citing works

Cooperative binding of Ets-1 and core binding factor to DNA

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PEBP2/CBF, the Murine Homolog of the Human Myeloid AML1 and PEBP2β/CBFβ Proto-oncoproteins, Regulates the Murine Myeloperoxidase and Neutrophil Elastase Genes in Immature Myeloid Cells

Nuchprayoon, I., Meyers, S., Scott, L. M., Suzow, J. G., Hiebert, S. W., & Friedman, A. D. (1994) · Molecular and Cellular Biology · doi:10.1128/mcb.14.8.5558-5568.1994 · Cited by 52 · see citing works

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Transcriptional Regulation of the Transforming Growth Factor-β-inducible Mouse Germ Line Ig α Constant Region Gene by Functional Cooperation of Smad, CREB, and AML Family Members

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Synergistic up-regulation of the myeloid-specific promoter for the macrophage colony-stimulating factor receptor by AML1 and the t(8;21) fusion protein may contribute to leukemogenesis.

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The C/EBP family of transcription factors in the liver and other organs

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Functional and Physical Interactions between AML1 Proteins and an ETS Protein, MEF: Implications for the Pathogenesis of t(8;21)-Positive Leukemias

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Roles of HIPK1 and HIPK2 in AML1‐ and p300‐dependent transcription, hematopoiesis and blood vessel formation

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Hoxa9 Immortalizes a Granulocyte-Macrophage Colony-Stimulating Factor-Dependent Promyelocyte Capable of Biphenotypic Differentiation to Neutrophils or Macrophages, Independent of Enforced Meis Expression

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PU.1 determines the self-renewal capacity of erythroid progenitor cells

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TLE, the Human Homolog of Groucho, Interacts with AML1 and Acts as a Repressor of AML1-Induced Transactivation

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Novel Combinatorial Interactions of GATA-1, PU.1, and C/EBPε Isoforms Regulate Transcription of the Gene Encoding Eosinophil Granule Major Basic Protein

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Distinct C/EBP functions are required for eosinophil lineage commitment and maturation

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The C/EBPδ tumor suppressor is silenced by hypermethylation in acute myeloid leukemia

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Origin, development, and homeostasis of tissue‐resident macrophages

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C/EBPα deficiency results in hyperproliferation of hematopoietic progenitor cells and disrupts macrophage development in vitro and in vivo

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Cross-Talk with Myeloid Accessory Cells Regulates Human Natural Killer Cell Interferon-γ Responses to Malaria

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Leukemogenic nucleophosmin mutation disrupts the transcription factor hub that regulates granulomonocytic fates

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Transcription factor fusions in acute leukemia: variations on a theme

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AML1 Is Functionally Regulated through p300-mediated Acetylation on Specific Lysine Residues

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Regulation of eosinophil‐specific gene expression by a C/EBP–Ets complex and GATA‐1

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Mutations of CEBPA in acute myeloid leukemia FAB types M1 and M2

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M-CSF increases proliferation and phagocytosis while modulating receptor and transcription factor expression in adult human microglia

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Cbfa1 in bone development

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Integrin engagement regulates monocyte differentiation through the forkhead transcription factor Foxp1

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The t(3;21) Fusion Product, AML1/Evi-1, Interacts With Smad3 and Blocks Transforming Growth Factor-β–Mediated Growth Inhibition of Myeloid Cells

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Functional Cooperation between CCAAT/Enhancer-Binding Proteins and the Vitamin D Receptor in Regulation of 25-Hydroxyvitamin D 3 24-Hydroxylase

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Identification of a Region Which Directs the Monocytic Activity of the Colony-Stimulating Factor 1 (Macrophage Colony-Stimulating Factor) Receptor Promoter and Binds PEBP2/CBF (AML1)

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Analysis of the Modulation of Transcriptional Activity in Myelopoiesis and Leukemogenesis

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Function of PU.1 (Spi-1), C/EBP, and AML1 in Early Myelopoiesis: Regulation of Multiple Myeloid CSF Receptor Promoters

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PU.1 (Spi-1) and C/EBPα Regulate Expression of the Granulocyte-Macrophage Colony-Stimulating Factor Receptor α Gene

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Synergistic up-regulation of the myeloid-specific promoter for the macrophage colony-stimulating factor receptor by AML1 and the t(8;21) fusion protein may contribute to leukemogenesis.

Rhoades, K. L., Hetherington, C. J., Rowley, J. D., Hiebert, S. W., Nucifora, G., Tenen, D. G., & Zhang, D. E. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.21.11895 · Cited by 129 · see citing works