Sartorelli, Vittorio

The NAD+-Dependent SIRT1 Deacetylase Translates a Metabolic Switch into Regulatory Epigenetics in Skeletal Muscle Stem Cells

Ryall, J. G., Dell’Orso, S., Derfoul, A., Juan, A., Zare, H., Feng, X., Clermont, D., Koulnis, M., Gutierrez-Cruz, G., Fulco, M., et al. (2015) · Cell Stem Cell

Sirtuins and Resveratrol in MedicineMuscle Physiology and Disorders

Cited by 575

H3K4 mono- and di-methyltransferase MLL4 is required for enhancer activation during cell differentiation

Lee, J.-E., Wang, C., Xu, S., Cho, Y.-W., Wang, L., Feng, X., Baldridge, A., Sartorelli, V., Zhuang, L., Peng, W., et al. (2013) · eLife

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 522

twist is a potential oncogene that inhibits apoptosis

Maestro, R., Tos, A. P. D., Hamamori, Y., Krasnokutsky, S., Sartorelli, V., Kedes, L., Doglioni, C., Beach, D. H., & Hannon, G. J. (1999) · Genes & Development

Cancer-related Molecular PathwaysCell death mechanisms and regulation

Cited by 516

Regulation of the p300 HAT domain via a novel activation loop

Thompson, P. R., Wang, D., Wang, L., Fulco, M., Pediconi, N., Zhang, D., An, W., Ge, Q., Roeder, R. G., Wong, J., et al. (2004) · Nature Structural & Molecular Biology

Genomics and Chromatin DynamicsHistone Deacetylase Inhibitors Research

Cited by 423

TNF/p38α/Polycomb Signaling to Pax7 Locus in Satellite Cells Links Inflammation to the Epigenetic Control of Muscle Regeneration

Palacios, D., Mozzetta, C., Consalvi, S., Caretti, G., Saccone, V., Proserpio, V., Marquez, V. E., Valente, S., Mai, A., Forcales, S. V., et al. (2010) · Cell Stem Cell

Muscle Physiology and DisordersGenomics and Chromatin Dynamics

Cited by 392

Regulation of Histone Acetyltransferases p300 and PCAF by the bHLH Protein Twist and Adenoviral Oncoprotein E1A

Hamamori, Y., Sartorelli, V., Ogryzko, V., Puri, P. L., Wu, H.-Y., Wang, J. Y. J., Nakatani, Y., & Kedes, L. (1999) · Cell

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 368

Single cell analysis of adult mouse skeletal muscle stem cells in homeostatic and regenerative conditions

Dell'Orso, S., Juan, A. H., Ko, K.-D., Naz, F., Perovanovic, J., Gutierrez-Cruz, G., Feng, X., & Sartorelli, V. (2019) · Development

Muscle Physiology and DisordersSingle-cell and spatial transcriptomics

Cited by 243

FoxO maintains a genuine muscle stem-cell quiescent state until geriatric age

García-Prat, L., Perdiguero, E., Alonso-Martín, S., Dell’Orso, S., Ravichandran, S., Brooks, S. R., Juan, A. H., Campanario, S., Jiang, K., Hong, X., et al. (2020) · Nature Cell Biology

Muscle Physiology and DisordersFOXO transcription factor regulation

Cited by 161

Epigenetic targeting of bromodomain protein BRD4 counteracts cancer cachexia and prolongs survival

Segatto, M., Fittipaldi, R., Pin, F., Sartori, R., Dae Ko, K., Zare, H., Fenizia, C., Zanchettin, G., Pierobon, E. S., Hatakeyama, S., et al. (2017) · Nature Communications

Muscle Physiology and DisordersNutrition and Health in Aging

Cited by 101

Dietary restriction: standing up for sirtuins

Baur, J. A., Chen, D., Chini, E. N., Chua, K., Cohen, H. Y., Cabo, R. D., Deng, C., Dimmeler, S., Gius, D., Guarente, L. P., et al. (2010) · Science

Sirtuins and Resveratrol in MedicineGenetics, Aging, and Longevity in Model Organisms

Cited by 76

Integrated expression analysis of muscle hypertrophy identifies Asb2 as a negative regulator of muscle mass

Davey, J. R., Watt, K. I., Parker, B. L., Chaudhuri, R., Ryall, J. G., Cunningham, L., Qian, H., Sartorelli, V., Sandri, M., Chamberlain, J., et al. (2016) · JCI Insight

Muscle Physiology and DisordersTGF-β signaling in diseases

Cited by 51