Wells, Dagan

Genome editing reveals a role for OCT4 in human embryogenesis

Fogarty, N. M. E., McCarthy, A., Snijders, K. E., Powell, B. E., Kubikova, N., Blakeley, P., Lea, R., Elder, K., Wamaitha, S. E., Kim, D., et al. (2017) · Nature

Pluripotent Stem Cells ResearchCRISPR and Genetic Engineering

Cited by 392

The origin and impact of embryonic aneuploidy

Fragouli, E., Alfarawati, S., Spath, K., Jaroudi, S., Sarasa, J., Enciso, M., & Wells, D. (2013) · Human Genetics

Reproductive Biology and FertilityPrenatal Screening and Diagnostics

Cited by 290

Frequent loss of heterozygosity in CRISPR-Cas9–edited early human embryos

Alanis-Lobato, G., Zohren, J., McCarthy, A., Fogarty, N. M. E., Kubikova, N., Hardman, E., Greco, M., Wells, D., Turner, J. M. A., & Niakan, K. K. (2021) · Proceedings of the National Academy of Sciences

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 234

Morphological and cytogenetic assessment of cleavage and blastocyst stage embryos

Fragouli, E., Alfarawati, S., Spath, K., & Wells, D. (2014) · Molecular Human Reproduction

Prenatal Screening and DiagnosticsReproductive Biology and Fertility

Cited by 189

The incidence and origin of segmental aneuploidy in human oocytes and preimplantation embryos

Babariya, D., Fragouli, E., Alfarawati, S., Spath, K., & Wells, D. (2017) · Human Reproduction

Prenatal Screening and DiagnosticsReproductive Biology and Fertility

Cited by 142

Investigation of sperm telomere length as a potential marker of paternal genome integrity and semen quality

Cariati, F., Jaroudi, S., Alfarawati, S., Raberi, A., Alviggi, C., Pivonello, R., & Wells, D. (2016) · Reproductive BioMedicine Online

Sperm and Testicular FunctionTelomeres, Telomerase, and Senescence

Cited by 78

Clinical application of a protocol based on universal next-generation sequencing for the diagnosis of beta-thalassaemia and sickle cell anaemia in preimplantation embryos

Kubikova, N., Babariya, D., Sarasa, J., Spath, K., Alfarawati, S., & Wells, D. (2018) · Reproductive BioMedicine Online

Prenatal Screening and DiagnosticsHemoglobinopathies and Related Disorders

Cited by 16