Thakkar, Shraddha

DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans

Chen, M., Suzuki, A., Thakkar, S., Yu, K., Hu, C., & Tong, W. (2016) · Drug Discovery Today

Drug-Induced Hepatotoxicity and ProtectionComputational Drug Discovery Methods

Cited by 398

Drug-induced liver injury severity and toxicity (DILIst): binary classification of 1279 drugs by human hepatotoxicity

Thakkar, S., Li, T., Liu, Z., Wu, L., Roberts, R., & Tong, W. (2020) · Drug Discovery Today

Drug-Induced Hepatotoxicity and ProtectionComputational Drug Discovery Methods

Cited by 140

Study of serious adverse drug reactions using FDA-approved drug labeling and MedDRA

Wu, L., Ingle, T., Liu, Z., Zhao-Wong, A., Harris, S., Thakkar, S., Zhou, G., Yang, J., Xu, J., Mehta, D., et al. (2019) · BMC Bioinformatics

Pharmacovigilance and Adverse Drug ReactionsBiomedical Text Mining and Ontologies

Cited by 80

FDALabel for drug repurposing studies and beyond

Fang, H., Harris, S., Liu, Z., Thakkar, S., Yang, J., Ingle, T., Xu, J., Lesko, L., Rosario, L., & Tong, W. (2020) · Nature Biotechnology

Computational Drug Discovery MethodsPharmacovigilance and Adverse Drug Reactions

Cited by 19

A framework enabling LLMs into regulatory environment for transparency and trustworthiness and its application to drug labeling document

Wu, L., Xu, J., Thakkar, S., Gray, M., Qu, Y., Li, D., & Tong, W. (2024) · Regulatory Toxicology and Pharmacology

Topic ModelingArtificial Intelligence in Healthcare and Education

Cited by 16

Automatic text classification of drug-induced liver injury using document-term matrix and XGBoost

Chen, M., Wu, Y., Wingerd, B., Liu, Z., Xu, J., Thakkar, S., Pedersen, T. J., Donnelly, T., Mann, N., Tong, W., et al. (2024) · Frontiers in Artificial Intelligence

Pharmacovigilance and Adverse Drug ReactionsText and Document Classification Technologies

Cited by 8