Biragyn, Arya

The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease

Youm, Y.-H., Nguyen, K. Y., Grant, R. W., Goldberg, E. L., Bodogai, M., Kim, D., D'Agostino, D., Planavsky, N., Lupfer, C., Kanneganti, T. D., et al. (2015) · Nature Medicine

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 2,172

Mammalian defensins in immunity: more than just microbicidal

Yang, D., Biragyn, A., Kwak, L. W., & Oppenheim, J. J. (2002) · Trends in Immunology

Antimicrobial Peptides and ActivitiesChemokine receptors and signaling

Cited by 696

Multiple roles of antimicrobial defensins, cathelicidins, and eosinophil-derived neurotoxin in host defense

Yang, D., Biragyn, A., Hoover, D. M., Lubkowski, J., & Oppenheim, J. J. (2004) · Annual Review of Immunology

Antimicrobial Peptides and ActivitiesImmune Response and Inflammation

Cited by 572

Identification of senescent cell surface targetable protein DPP4

Kim, K. M., Noh, J. H., Bodogai, M., Martindale, J. L., Yang, X., Indig, F. E., Basu, S. K., Ohnuma, K., Morimoto, C., Johnson, P. F., et al. (2017) · Genes & Development

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 270

Therapeutic B-cell depletion reverses progression of Alzheimer’s disease

Kim, K., Wang, X., Ragonnaud, E., Bodogai, M., Illouz, T., DeLuca, M., McDevitt, R. A., Gusev, F., Okun, E., Rogaev, E., et al. (2021) · Nature Communications

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 206

Commensal bacteria contribute to insulin resistance in aging by activating innate B1a cells

Bodogai, M., O’Connell, J., Kim, K., Kim, Y., Moritoh, K., Chen, C., Gusev, F., Vaughan, K., Shulzhenko, N., Mattison, J. A., et al. (2018) · Science Translational Medicine

Gut microbiota and healthAdipokines, Inflammation, and Metabolic Diseases

Cited by 182

Accumulation of 4-1BBL+ B cells in the elderly induces the generation of granzyme-B+ CD8+ T cells with potential antitumor activity

Lee-Chang, C., Bodogai, M., Moritoh, K., Olkhanud, P. B., Chan, A. C., Croft, M., Mattison, J. A., Holst, P. J., Gress, R. E., Ferrucci, L., et al. (2014) · Blood

T-cell and B-cell ImmunologyImmunotherapy and Immune Responses

Cited by 58

Dexamethasone augments CXCR4-mediated signaling in resting human T cells via the activation of the Src kinase Lck

Ghosh, M. C., Baatar, D., Collins, G., Carter, A., Indig, F., Biragyn, A., & Taub, D. D. (2009) · Blood

Chemokine receptors and signalingT-cell and B-cell Immunology

Cited by 49

Potential importance of B cells in aging and aging-associated neurodegenerative diseases

Biragyn, A., Aliseychik, M., & Rogaev, E. (2017) · Seminars in Immunopathology

Neuroinflammation and Neurodegeneration MechanismsT-cell and B-cell Immunology

Cited by 25

Restoring microglial and astroglial homeostasis using DNA immunization in a down Syndrome mouse model.

Illouz, T., Madar, R., Biragyn, A., & Okun, E. (2019) · Brain, Behavior, and Immunity

Alzheimer's disease research and treatmentsDown syndrome and intellectual disability research

Cited by 22

Maternal antibodies facilitate Amyloid-β clearance by activating Fc-receptor-Syk-mediated phagocytosis

Illouz, T., Nicola, R., Ben-Shushan, L., Madar, R., Biragyn, A., & Okun, E. (2021) · Communications Biology

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 21