Lenardo, Michael J.

A guide to cancer immunotherapy: from T cell basic science to clinical practice

Waldman, A. D., Fritz, J. M., & Lenardo, M. J. (2020) · Nature Reviews Immunology

Cancer Immunotherapy and BiomarkersImmunotherapy and Immune Responses

Cited by 4,154

The TNF and TNF Receptor Superfamilies

Locksley, R. M., Killeen, N., & Lenardo, M. J. (2001) · Cell

Cell death mechanisms and regulationNF-κB Signaling Pathways

Cited by 3,650

Inborn errors of type I IFN immunity in patients with life-threatening COVID-19

Zhang, Q., Bastard, P., Liu, Z., Le Pen, J., Moncada-Velez, M., Chen, J., Ogishi, M., Sabli, I. K. D., Hodeib, S., Korol, C., et al. (2020) · Science

interferon and immune responsesSARS-CoV-2 and COVID-19 Research

Cited by 2,229

Termination of autophagy and reformation of lysosomes regulated by mTOR

Yu, L., McPhee, C. K., Zheng, L., Mardones, G. A., Rong, Y., Peng, J., Mi, N., Zhao, Y., Liu, Z., Wan, F., et al. (2010) · Nature

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 1,544

A Domain in TNF Receptors That Mediates Ligand-Independent Receptor Assembly and Signaling

Chan, F. K.-M., Chun, H. J., Zheng, L., Siegel, R. M., Bui, K. L., & Lenardo, M. J. (2000) · Science

NF-κB Signaling PathwaysCytokine Signaling Pathways and Interactions

Cited by 856

Spinster is required for autophagic lysosome reformation and mTOR reactivation following starvation

Rong, Y., McPhee, C. K., Deng, S., Huang, L., Chen, L., Liu, M., Tracy, K., Baehrecke, E. H., Yu, L., & Lenardo, M. J. (2011) · Proceedings of the National Academy of Sciences

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 273

Essential Role for Caspase-8 in Toll-like Receptors and NFκB Signaling

Lemmers, B., Salmena, L., Bidère, N., Su, H., Matysiak-Zablocki, E., Murakami, K., Ohashi, P. S., Jurisicova, A., Lenardo, M., Hakem, R., et al. (2007) · Journal of Biological Chemistry

NF-κB Signaling PathwaysImmune Response and Inflammation

Cited by 181

HEM1 deficiency disrupts mTORC2 and F-actin control in inherited immunodysregulatory disease

Cook, S. A., Comrie, W. A., Poli, M. C., Similuk, M., Oler, A. J., Faruqi, A. J., Kuhns, D. B., Yang, S., Vargas-Hernández, A., Carisey, A. F., et al. (2020) · Science

Immunodeficiency and Autoimmune DisordersPI3K/AKT/mTOR signaling in cancer

Cited by 102

HEM1 Actin Immunodysregulatory Disorder: Genotypes, Phenotypes, and Future Directions

Cook, S., Lenardo, M. J., & Freeman, A. F. (2022) · Journal of Clinical Immunology

Immunodeficiency and Autoimmune DisordersBlood disorders and treatments

Cited by 24

Genetic immunodeficiency and autoimmune disease reveal distinct roles of Hem1 in the WAVE2 and mTORC2 complexes

Comrie, W. A., Poli, M. C., Cook, S. A., Similuk, M., Oler, A. J., Faruqi, A. J., Kuhns, D. B., Yang, S., Carisey, A. F., Fournier, B., et al. (2019) · bioRxiv (Cold Spring Harbor Laboratory)

Immunodeficiency and Autoimmune DisordersT-cell and B-cell Immunology

Cited by 3