Casaccia, Patrizia

Impaired adult myelination in the prefrontal cortex of socially isolated mice

Liu, J., Dietz, K., DeLoyht, J. M., Pedre, X., Kelkar, D., Kaur, J., Vialou, V., Lobo, M. K., Dietz, D. M., Nestler, E. J., et al. (2012) · Nature Neuroscience

Neurogenesis and neuroplasticity mechanismsNeuroscience and Neuropharmacology Research

Cited by 685

Brain Cell Type Specific Gene Expression and Co-expression Network Architectures

McKenzie, A. T., Wang, M., Hauberg, M. E., Fullard, J. F., Kozlenkov, A., Keenan, A., Hurd, Y. L., Dracheva, S., Casaccia, P., Roussos, P., et al. (2018) · Scientific Reports

Single-cell and spatial transcriptomicsGene expression and cancer classification

Cited by 481

Integrative network analysis of nineteen brain regions identifies molecular signatures and networks underlying selective regional vulnerability to Alzheimer’s disease

Wang, M., Roussos, P., McKenzie, A., Zhou, X., Kajiwara, Y., Brennand, K. J., De Luca, G. C., Crary, J. F., Casaccia, P., Buxbaum, J. D., et al. (2016) · Genome Medicine

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 314

Microbiota-driven transcriptional changes in prefrontal cortex override genetic differences in social behavior

Gacias, M., Gaspari, S., Santos, P.-M. G., Tamburini, S., Andrade, M., Zhang, F., Shen, N., Tolstikov, V., Kiebish, M. A., Dupree, J. L., et al. (2016) · eLife

Gut microbiota and healthTryptophan and brain disorders

Cited by 308

Astrocyte-shed extracellular vesicles regulate the peripheral leukocyte response to inflammatory brain lesions

Dickens, A. M., Tovar-y-Romo, L. B., Yoo, S.-W., Trout, A. L., Bae, M., Kanmogne, M., Megra, B., Williams, D. W., Witwer, K. W., Gacias, M., et al. (2017) · Science Signaling

Extracellular vesicles in diseaseNeuroinflammation and Neurodegeneration Mechanisms

Cited by 285

Common dysregulation network in the human prefrontal cortex underlies two neurodegenerative diseases

Narayanan, M., Huynh, J. L., Wang, K., Yang, X., Yoo, S., McElwee, J., Zhang, B., Zhang, C., Lamb, J. R., Xie, T., et al. (2014) · Molecular Systems Biology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 208

Multiscale network modeling of oligodendrocytes reveals molecular components of myelin dysregulation in Alzheimer’s disease

McKenzie, A. T., Moyon, S., Wang, M., Katsyv, I., Song, W.-M., Zhou, X., Dammer, E. B., Duong, D. M., Aaker, J., Zhao, Y., et al. (2017) · Molecular Neurodegeneration

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 154

Region-specific myelin differences define behavioral consequences of chronic social defeat stress in mice

Bonnefil, V., Dietz, K., Amatruda, M., Wentling, M., Aubry, A. V., Dupree, J. L., Temple, G., Park, H.-J., Burghardt, N. S., Casaccia, P., et al. (2019) · eLife

Neurogenesis and neuroplasticity mechanismsStress Responses and Cortisol

Cited by 123

Identification of a Gene Regulatory Network Necessary for the Initiation of Oligodendrocyte Differentiation

Swiss, V. A., Nguyen, T., Dugas, J., Ibrahim, A., Barres, B., Androulakis, I. P., & Casaccia, P. (2011) · PLoS ONE

Neurogenesis and neuroplasticity mechanismsHistone Deacetylase Inhibitors Research

Cited by 112

Huntington disease oligodendrocyte maturation deficits revealed by single-nucleus RNAseq are rescued by thiamine-biotin supplementation

Lim, R. G., Al-Dalahmah, O., Wu, J., Gold, M. P., Reidling, J. C., Tang, G., Adam, M., Dansu, D. K., Park, H.-J., Casaccia, P., et al. (2022) · Nature Communications

Genetic Neurodegenerative DiseasesNeurogenesis and neuroplasticity mechanisms

Cited by 84

Widespread transcriptional alternations in oligodendrocytes in the adult mouse brain following chronic stress

Liu, J., Dietz, K., Hodes, G. E., Russo, S. J., & Casaccia, P. (2018) · Developmental Neurobiology

Neurogenesis and neuroplasticity mechanismsStress Responses and Cortisol

Cited by 75

Patient iPSC models reveal glia-intrinsic phenotypes in multiple sclerosis

Clayton, B. L. L., Barbar, L., Sapar, M., Kalpana, K., Rao, C., Migliori, B., Rusielewicz, T., Paull, D., Brenner, K., Moroziewicz, D., et al. (2024) · Cell Stem Cell

Multiple Sclerosis Research StudiesPluripotent Stem Cells Research

Cited by 38

N‐myc downstream regulated family member 1 (NDRG1) is enriched in myelinating oligodendrocytes and impacts myelin degradation in response to demyelination

Marechal, D., Dansu, D. K., Castro, K., Patzig, J., Magri, L., Inbar, B., Gacias, M., Moyon, S., & Casaccia, P. (2022) · Glia

Neurogenesis and neuroplasticity mechanismsMultiple Sclerosis Research Studies

Cited by 17