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In sickness and in health: The functional role of extracellular vesicles in physiology and pathology in vivo

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Microglia and Astrocyte Function and Communication: What Do We Know in Humans?

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Tetraspanins are unevenly distributed across single extracellular vesicles and bias sensitivity to multiplexed cancer biomarkers

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Integrated care for optimizing the management of stroke and associated heart disease: a position paper of the European Society of Cardiology Council on Stroke

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Recent advances in drug delivery and targeting to the brain

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Astrocyte, a Promising Target for Mood Disorder Interventions

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Stimulus‐dependent modifications in astrocyte‐derived extracellular vesicle cargo regulate neuronal excitability

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Exosomes From Astrocyte Processes: Signaling to Neurons

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L1CAM-associated extracellular vesicles: A systematic review of nomenclature, sources, separation, and characterization

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Astrocyte-derived small extracellular vesicles promote synapse formation via fibulin-2-mediated TGF-β signaling

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Reactive Astrocytes in Brain Metastasis

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Astrocyte EV-Induced lincRNA-Cox2 Regulates Microglial Phagocytosis: Implications for Morphine-Mediated Neurodegeneration

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Microglia-Astrocyte Communication in Alzheimer’s Disease

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Extracellular Vesicles as an Emerging Frontier in Spinal Cord Injury Pathobiology and Therapy

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Pharmacological potential of the combination of Salvia miltiorrhiza (Danshen) and Carthamus tinctorius (Honghua) for diabetes mellitus and its cardiovascular complications

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Extracellular Vesicles in neural cell interaction and CNS homeostasis

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Astrocyte- and Neuron-Derived Extracellular Vesicles from Alzheimer’s Disease Patients Effect Complement-Mediated Neurotoxicity

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Spinal cord injury alters microRNA and CD81+ exosome levels in plasma extracellular nanoparticles with neuroinflammatory potential

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Extracellular vesicles as personalized medicine

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Proteomic analysis of cerebrospinal fluid extracellular vesicles reveals synaptic injury, inflammation, and stress response markers in HIV patients with cognitive impairment

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Astrocyte-derived extracellular vesicles: A double-edged sword in central nervous system disorders

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The Function of Astrocyte Mediated Extracellular Vesicles in Central Nervous System Diseases

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Immunotherapy in NSCLC patients with brain metastases. Understanding brain tumor microenvironment and dissecting outcomes from immune checkpoint blockade in the clinic

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Recent insights on astrocyte mechanisms in CNS homeostasis, pathology, and repair

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Small Extracellular Vesicles in Rat Serum Contain Astrocyte-Derived Protein Biomarkers of Repetitive Stress

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Emergence of Extracellular Vesicles as “Liquid Biopsy” for Neurological Disorders: Boom or Bust

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Exosomal miR-9 Released from HIV Tat Stimulated Astrocytes Mediates Microglial Migration

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Native and Bioengineered Exosomes for Ischemic Stroke Therapy

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Mechanisms of axonal support by oligodendrocyte-derived extracellular vesicles

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Extracellular vesicles set the stage for brain plasticity and recovery by multimodal signalling

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Neutrophil–Lymphocyte Ratio and Perihematomal Edema Growth in Intracerebral Hemorrhage

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Exacerbation of Acute Traumatic Brain Injury by Circulating Extracellular Vesicles

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Neuron-derived extracellular vesicles in blood reveal effects of exercise in Alzheimer’s disease

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Extracellular vesicles and chronic inflammation during HIV infection

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Fibroblast Growth Factor 2‐Mediated Regulation of Neuronal Exosome Release Depends on VAMP3/Cellubrevin in Hippocampal Neurons

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Exosome-mediated amplification of endogenous brain repair mechanisms and brain and systemic organ interaction in modulating neurological outcome after stroke

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DPTIP, a newly identified potent brain penetrant neutral sphingomyelinase 2 inhibitor, regulates astrocyte-peripheral immune communication following brain inflammation

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Engineered extracellular vesicles as brain therapeutics

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Interleukin-3 coordinates glial-peripheral immune crosstalk to incite multiple sclerosis

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α-Synuclein-carrying astrocytic extracellular vesicles in Parkinson pathogenesis and diagnosis

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HIV-1 Tat-Induced Astrocytic Extracellular Vesicle miR-7 Impairs Synaptic Architecture

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Trends in the biological functions and medical applications of extracellular vesicles and analogues

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Neutral Sphingomyelinase Inhibition Alleviates LPS-Induced Microglia Activation and Neuroinflammation after Experimental Traumatic Brain Injury

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Systemic Immune Response to Traumatic CNS Injuries—Are Extracellular Vesicles the Missing Link?

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T he roles of extracellular vesicle micro RNA s in the central nervous system

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Extracellular Vesicles in Mental Disorders: A State-of-art Review

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A transgenic inducible GFP extracellular-vesicle reporter (TIGER) mouse illuminates neonatal cortical astrocytes as a source of immunomodulatory extracellular vesicles

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Extracellular vesicles and Alzheimer’s disease in the novel era of Precision Medicine: implications for disease progression, diagnosis and treatment

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Circulating endothelial cell-derived extracellular vesicles mediate the acute phase response and sickness behaviour associated with CNS inflammation

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Extracellular Vesicles miRNA Cargo for Microglia Polarization in Traumatic Brain Injury

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Extracellular Vesicles and the Stress System

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Long noncoding RNA NKILA transferred by astrocyte-derived extracellular vesicles protects against neuronal injury by upregulating NLRX1 through binding to mir-195 in traumatic brain injury

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Extracellular vesicles: translational research and applications in neurology

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Validation of reference genes for expression analysis in a murine trauma model combining traumatic brain injury and femoral fracture

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Tumor Immune Microenvironment of Brain Metastases: Toward Unlocking Antitumor Immunity

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Neuroinflammation of traumatic brain injury: Roles of extracellular vesicles

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Novel Human Neutral Sphingomyelinase 2 Inhibitors as Potential Therapeutics for Alzheimer’s Disease

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Methamphetamine use alters human plasma extracellular vesicles and their microRNA cargo: An exploratory study

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Insights Into the Proteomic Profiling of Extracellular Vesicles for the Identification of Early Biomarkers of Neurodegeneration

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Systemic inflammation status at admission affects the outcome of intracerebral hemorrhage by increasing perihematomal edema but not the hematoma growth

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Astrocytes deliver CK1 to neurons via extracellular vesicles in response to inflammation promoting the translation and amyloidogenic processing of APP

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Extracellular Vesicles at CNS barriers: Mode of action

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Extracellular vesicles for targeted drug delivery: advances in surface modification strategies and therapeutic applications

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A novel and potent brain penetrant inhibitor of extracellular vesicle release

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Emerging role of extracellular vesicles in diabetic retinopathy

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Clinical Applications of Extracellular Vesicles in the Diagnosis and Treatment of Traumatic Brain Injury

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Differential Effects of APOE Genotype on MicroRNA Cargo of Cerebrospinal Fluid Extracellular Vesicles in Females With Alzheimer’s Disease Compared to Males

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Role of Crosstalk between Glial Cells and Immune Cells in Blood-Brain Barrier Damage and Protection after Acute Ischemic Stroke

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Understanding the heart-brain axis response in COVID-19 patients: A suggestive perspective for therapeutic development

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Extracellular vesicle-mediated bidirectional communication between heart and other organs

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Inhibition of neutral sphingomyelinase 2 reduces extracellular vesicle release from neurons, oligodendrocytes, and activated microglial cells following acute brain injury

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Characterization of Extracellular Vesicles from Human Saliva: Effects of Age and Isolation Techniques

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Extracellular vesicles as mediators and markers of acute organ injury: current concepts

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Secretome of Stem Cells: Roles of Extracellular Vesicles in Diseases, Stemness, Differentiation, and Reprogramming

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The Role of Exosomes in the Crosstalk between Adipocytes and Liver Cancer Cells

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Small but Mighty—Exosomes, Novel Intercellular Messengers in Neurodegeneration

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The emerging role of exosomes in communication between the periphery and the central nervous system

Han, W., Zhang, H., Feng, L., Dang, R., Wang, J., Cui, C., & Jiang, P. (2023) · MedComm · doi:10.1002/mco2.410 · Cited by 38 · see citing works

Brain incoming call from glia during neuroinflammation: Roles of extracellular vesicles

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Bidirectional Communication Between the Brain and Other Organs: The Role of Extracellular Vesicles

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Improved post-stroke spontaneous recovery by astrocytic extracellular vesicles

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Immune signals packaged in the brain

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Proteomic, transcriptomic and functional characterization of human astrocyte‐derived extracellular vesicles upon inflammatory activation

You, Y., Borgmann, K., Edara, V., Stacy, S., Ghorpade, A., & Ikezu, T. (2020) · Alzheimer s & Dementia · doi:10.1002/alz.039585

Activated human astrocyte‐derived extracellular vesicles modulate neuronal uptake, differentiation and firing

You, Y., Borgmann, K., Edara, V. V., Stacy, S., Ghorpade, A., & Ikezu, T. (2020) · Journal of Extracellular Vesicles · doi:10.1080/20013078.2019.1706801 · Cited by 176 · see citing works

Identification of a novel mechanism of blood–brain communication during peripheral inflammation via choroid plexus‐derived extracellular vesicles

Balusu, S., Wonterghem, E. V., Rycke, R. M. D., Raemdonck, K., Stremersch, S., Gevaert, K., Brkić, M., Demeestere, D., Vanhooren, V., Hendrix, A., et al. (2016) · EMBO Molecular Medicine · doi:10.15252/emmm.201606271 · Cited by 348 · see citing works

TNFα and IL-1β modify the miRNA cargo of astrocyte shed extracellular vesicles to regulate neurotrophic signaling in neurons

Chaudhuri, A. D., Dastgheyb, R. M., Yoo, S.-W., Trout, A., Talbot Jr, C. C., Hao, H., Witwer, K. W., & Haughey, N. J. (2018) · Cell Death & Disease · doi:10.1038/s41419-018-0369-4 · Cited by 184 · see citing works