Yan, Zhen

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1

Klionsky, D. J., Abdel-Aziz, A. K., Abdelfatah, S., Abdellatif, M., Abdoli, A., Abel, S., Abeliovich, H., Abildgaard, M. H., Abudu, Y. P., Acevedo-Arozena, A., et al. (2021) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 2,897

Exercise Stimulates Pgc-1α Transcription in Skeletal Muscle through Activation of the p38 MAPK Pathway

Akimoto, T., Pohnert, S. C., Li, P., Zhang, M., Gumbs, C., Rosenberg, P. B., Williams, R. S., & Yan, Z. (2005) · Journal of Biological Chemistry

Muscle Physiology and DisordersAdipose Tissue and Metabolism

Cited by 714

A PGC-1α isoform induced by resistance training regulates skeletal muscle hypertrophy

Ruas, J. L., White, J. P., Rao, R. R., Kleiner, S., Brannan, K. T., Harrison, B. C., Greene, N. P., Wu, J., Estall, J. L., Irving, B. A., et al. (2012) · Cell

Muscle Physiology and DisordersAdipose Tissue and Metabolism

Cited by 677

Skeletal muscle fiber-type switching, exercise intolerance, and myopathy in PGC-1α muscle-specific knock-out animals.

Handschin, C., Chin, S., Li, P., Liu, F., Maratos-Flier, E., LeBrasseur, N. K., Yan, Z., & Spiegelman, B. M. (2007) · Journal of Biological Chemistry

Muscle Physiology and DisordersAdipose Tissue and Metabolism

Cited by 611

Ampk phosphorylation of Ulk1 is required for targeting of mitochondria to lysosomes in exercise-induced mitophagy

Laker, R. C., Drake, J. C., Wilson, R. J., Lira, V. A., Lewellen, B. M., Ryall, K. A., Fisher, C. C., Zhang, M., Saucerman, J. J., Goodyear, L. J., et al. (2017) · Nature Communications

Autophagy in Disease and TherapyMetabolism, Diabetes, and Cancer

Cited by 529

Peroxisome Proliferator-activated Receptor-γ Co-activator 1α-mediated Metabolic Remodeling of Skeletal Myocytes Mimics Exercise Training and Reverses Lipid-induced Mitochondrial Inefficiency

Koves, T. R., Li, P., An, J., Akimoto, T., Slentz, D., Ilkayeva, O., Dohm, G. L., Yan, Z., Newgard, C. B., & Muoio, D. M. (2005) · Journal of Biological Chemistry

Adipose Tissue and MetabolismMetabolism, Diabetes, and Cancer

Cited by 464

Autophagy is required for exercise training‐induced skeletal muscle adaptation and improvement of physical performance

Lira, V. A., Okutsu, M., Zhang, M., Greene, N. P., Laker, R. C., Breen, D. S., Hoehn, K. L., & Yan, Z. (2013) · The FASEB Journal

Autophagy in Disease and TherapyMuscle Physiology and Disorders

Cited by 432

PGC-1α regulation by exercise training and its influences on muscle function and insulin sensitivity

Lira, V. A., Benton, C. R., Yan, Z., & Bonen, A. (2010) · American Journal of Physiology-Endocrinology and Metabolism

Adipose Tissue and MetabolismPeroxisome Proliferator-Activated Receptors

Cited by 412

P38 MAPK Links Oxidative Stress to Autophagy-Related Gene Expression in Cachectic Muscle Wasting

McClung, J. M., Judge, A. R., Powers, S. K., & Yan, Z. (2010) · American Journal of Physiology-Cell Physiology

Muscle Physiology and DisordersAutophagy in Disease and Therapy

Cited by 277

Total Skeletal Muscle PGC-1 Deficiency Uncouples Mitochondrial Derangements from Fiber Type Determination and Insulin Sensitivity

Zechner, C., Lai, L., Zechner, J. F., Geng, T., Yan, Z., Rumsey, J. W., Collia, D., Chen, Z., Wozniak, D. F., Leone, T. C., et al. (2010) · Cell Metabolism

Adipose Tissue and MetabolismMuscle Physiology and Disorders

Cited by 274

Molecular mechanisms for mitochondrial adaptation to exercise training in skeletal muscle

Drake, J. C., Wilson, R. J., & Yan, Z. (2016) · The FASEB Journal

Mitochondrial Function and PathologyAdipose Tissue and Metabolism

Cited by 263

PGC-1α plays a functional role in exercise-induced mitochondrial biogenesis and angiogenesis but not fiber-type transformation in mouse skeletal muscle

Geng, T., Li, P., Okutsu, M., Yin, X., Kwek, J., Zhang, M., & Yan, Z. (2010) · American Journal of Physiology-Cell Physiology

Adipose Tissue and MetabolismMuscle Physiology and Disorders

Cited by 263

Identification of a novel mitochondrial uncoupler that does not depolarize the plasma membrane

Kenwood, B. M., Weaver, J. L., Bajwa, A., Poon, I. K., Byrne, F. L., Murrow, B. A., Calderone, J. A., Huang, L., Divakaruni, A. S., Tomsig, J. L., et al. (2014) · Molecular Metabolism

Mitochondrial Function and PathologyATP Synthase and ATPases Research

Cited by 243

p38γ Mitogen-Activated Protein Kinase Is a Key Regulator in Skeletal Muscle Metabolic Adaptation in Mice

Pogozelski, A. R., Geng, T., Li, P., Yin, X., Lira, V. A., Zhang, M., Chi, J.-T., & Yan, Z. (2009) · PLoS ONE

Muscle Physiology and DisordersAdipose Tissue and Metabolism

Cited by 164

Baf60c drives glycolytic metabolism in the muscle and improves systemic glucose homeostasis through Deptor-mediated Akt activation

Meng, Z.-X., Li, S., Wang, L., Ko, H. J., Lee, Y., Jung, D. Y., Okutsu, M., Yan, Z., Kim, J. K., & Lin, J. D. (2013) · Nature Medicine

Metabolism, Diabetes, and CancerMuscle Physiology and Disorders

Cited by 146

Adeno-associated virus serotype 9 efficiently targets ischemic skeletal muscle following systemic delivery

Katwal, A. B., Konkalmatt, P. R., Piras, B. A., Hazarika, S., Li, S. S., John Lye, R., Sanders, J. M., Ferrante, E. A., Yan, Z., Annex, B. H., et al. (2013) · Gene Therapy

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 56

Protein phosphatase 2A is targeted to cell division control protein 6 by a calcium-binding regulatory subunit

Davis, A. J., Yan, Z., Martinez, B., & Mumby, M. C. (2008) · Journal of Biological Chemistry

Protein Kinase Regulation and GTPase SignalingCancer-related Molecular Pathways

Cited by 45

No effect of carbohydrate feeding on glycogen synthase in human muscle during exercise

Yan, Z., Spencer, M. K., & Katz, A. (1993) · Clinical Physiology

Muscle metabolism and nutritionMetabolism, Diabetes, and Cancer

Cited by 5