Boobis, Alan

Per- and Polyfluoroalkyl Substance Toxicity and Human Health Review: Current State of Knowledge and Strategies for Informing Future Research

Fenton, S. E., Ducatman, A., Boobis, A., DeWitt, J. C., Lau, C., Ng, C., Smith, J. S., & Roberts, S. M. (2020) · Environmental Toxicology and Chemistry

Per- and polyfluoroalkyl substances researchToxic Organic Pollutants Impact

Cited by 2,445

Methods of in vitro toxicology

Eisenbrand, G., Pool-Zobel, B., Baker, V, Balls, M., Blaauboer, B. J., Boobis, A., Carere, A., Kevekordes, S., Lhuguenot, J.-C., Pieters, R., et al. (2002) · Food and Chemical Toxicology

Carcinogens and Genotoxicity AssessmentAnimal testing and alternatives

Cited by 462

Scaling Factors for the Extrapolation of In Vivo Metabolic Drug Clearance From In Vitro Data: Reaching a Consensus on Values of Human Micro-somal Protein and Hepatocellularity Per Gram of Liver

Barter, Z., Bayliss, M., Beaune, P., Boobis, A., Carlile, D., Edwards, R., Brian Houston, J., Lake, B., Lipscomb, J., Pelkonen, O., et al. (2007) · Current Drug Metabolism

Pharmacogenetics and Drug MetabolismPharmaceutical studies and practices

Cited by 459

Cytochrome P450 expression in human hepatocytes and hepatoma cell lines: molecular mechanisms that determine lower expression in cultured cells

Rodríguez-Antona, C., Donato, M. T., Boobis, A., Edwards, R. J., Watts, P. S., Castell, J. V., & Gómez-Lechón, M.-J. (2002) · Xenobiotica

Pharmacogenetics and Drug MetabolismDrug Transport and Resistance Mechanisms

Cited by 420

Risk assessment of combined exposure to multiple chemicals: A WHO/IPCS framework

Meek, M. E., Boobis, A. R., Crofton, K. M., Heinemeyer, G., Raaij, M. V., & Vickers, C. (2011) · Regulatory Toxicology and Pharmacology

Agricultural safety and regulationsChemical Safety and Risk Management

Cited by 358

Towards microbial fermentation metabolites as markers for health benefits of prebiotics

Verbeke, K. A., Boobis, A. R., Chiodini, A., Edwards, C. A., Franck, A., Kleerebezem, M., Nauta, A., Raes, J., van Tol, E. A. F., & Tuohy, K. M. (2015) · Nutrition Research Reviews

Gut microbiota and healthMicrobial Metabolites in Food Biotechnology

Cited by 343

Comparative analysis of CYP3A expression in human liver suggests only a minor role for CYP3A5 in drug metabolism

Westlind-Johnsson, A., Malmebo, S., Johansson, A., Otter, C., Andersson, T. B., Johansson, I., Edwards, R. J., Boobis, A. R., & Ingelman-Sundberg, M. (2003) · Drug Metabolism and Disposition

Pharmacogenetics and Drug MetabolismDrug Transport and Resistance Mechanisms

Cited by 258

Overview on legislation and scientific approaches for risk assessment of combined exposure to multiple chemicals: the potential EuroMix contribution

Rotter, S., Beronius, A., Boobis, A. R., Hanberg, A., van Klaveren, J., Luijten, M., Machera, K., Nikolopoulou, D., van der Voet, H., Zilliacus, J., et al. (2018) · Critical Reviews in Toxicology

Agricultural safety and regulationsChemical Safety and Risk Management

Cited by 108

Cytochrome P450 3A expression in the human fetal liver: evidence that CYP3A5 is expressed in only a limited number of fetal livers

Hakkola, J., Raunio, H., Purkunen, R., Saarikoski, S., Vähäkangas, K., Pelkonen, O., Edwards, R. J., Boobis, A. R., & Pasanen, M. (2001) · Neonatology

Pharmacogenetics and Drug MetabolismDrug Transport and Resistance Mechanisms

Cited by 82

Human relevance of rodent liver tumors: Key insights from a Toxicology Forum workshop on nongenotoxic modes of action

Felter, S. P., Foreman, J. E., Boobis, A., Corton, J. C., Doi, A. M., Flowers, L., Goodman, J., Haber, L. T., Jacobs, A., Klaunig, J. E., et al. (2018) · Regulatory Toxicology and Pharmacology

Carcinogens and Genotoxicity AssessmentAgricultural safety and regulations

Cited by 80

Synergy between histone deacetylase inhibitors and DNA-damaging agents is mediated by histone deacetylase 2 in colorectal cancer

Alzoubi, S., Brody, L., Rahman, S., Mahul-Mellier, A.-L., Mercado, N., Ito, K., El-Bahrawy, M., Silver, A., Boobis, A., Bell, J. D., et al. (2016) · Oncotarget

Histone Deacetylase Inhibitors ResearchEpigenetics and DNA Methylation

Cited by 37

Genetic differences in the metabolism of carcinogens and in the binding of benzo[a]pyrene metabolites to DNA

Boobis, A. R., & Nebert, D. W. (1977) · Advances in Enzyme Regulation

Pharmacogenetics and Drug MetabolismCarcinogens and Genotoxicity Assessment

Cited by 12