Tooyama, Ikuo

Microglia in degenerative neurological disease

McGeer, P. L., Kawamata, T., Walker, D. G., Akiyama, H., Tooyama, I., & McGeer, E. G. (1993) · Glia

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 596

Reactive microglia express class I and class II major histocompatibility complex antigens in Alzheimer's disease

Tooyama, I., Kimura, H., Akiyama, H., & McGeer, P. L. (1990) · Brain Research

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 180

Expression of intercellular adhesion molecule (ICAM)-1 by a subset of astrocytes in Alzheimer disease and some other degenerative neurological disorders

Akiyama, H., Kawamata, T., Yamada, T., Tooyama, I., Ishii, T., & McGeer, P. L. (1993) · Acta Neuropathologica

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 137

Patterns of Expression of Purinergic Receptor P2RY12, a Putative Marker for Non-Activated Microglia, in Aged and Alzheimer’s Disease Brains

Walker, D. G., Tang, T. M., Mendsaikhan, A., Tooyama, I., Serrano, G. E., Sue, L. I., Beach, T. G., & Lue, L.-F. (2020) · International Journal of Molecular Sciences

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 128

Synergistic effect between proteasome and autophagosome in the clearance of polyubiquitinated TDP‐43

Urushitani, M., Sato, T., Bamba, H., Hisa, Y., & Tooyama, I. (2010) · Journal of Neuroscience Research

Amyotrophic Lateral Sclerosis ResearchAutophagy in Disease and Therapy

Cited by 114

Microglial Progranulin: Involvement in Alzheimer’s Disease and Neurodegenerative Diseases

Mendsaikhan, A., Tooyama, I., & Walker, D. G. (2019) · Cells

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 72

Axonal ligation induces transient redistribution of TDP-43 in brainstem motor neurons

Sato, T., Takeuchi, S., Saito, A., Ding, W., Bamba, H., Matsuura, H., Hisa, Y., Tooyama, I., & Urushitani, M. (2009) · Neuroscience

Amyotrophic Lateral Sclerosis ResearchHereditary Neurological Disorders

Cited by 63

Characterization of lysosomal proteins Progranulin and Prosaposin and their interactions in Alzheimer’s disease and aged brains: increased levels correlate with neuropathology

Mendsaikhan, A., Tooyama, I., Bellier, J.-P., Serrano, G. E., Sue, L. I., Lue, L.-F., Beach, T. G., & Walker, D. G. (2019) · Acta Neuropathologica Communications

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 57

Differential accumulation of tau pathology between reciprocal F1 hybrids of rTg4510 mice

Yanagisawa, D., Hamezah, H. S., Pahrudin Arrozi, A., & Tooyama, I. (2021) · Scientific Reports

Alzheimer's disease research and treatmentsAmyotrophic Lateral Sclerosis Research

Cited by 7