Rajewsky, Nikolaus

Circular RNAs are a large class of animal RNAs with regulatory potency

Memczak, S., Jens, M., Elefsinioti, A., Torti, F., Krueger, J., Rybak, A., Maier, L., Mackowiak, S. D., Gregersen, L. H., Munschauer, M., et al. (2013) · Nature

Circular RNAs in diseasesRNA Research and Splicing

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Combinatorial microRNA target predictions

Krek, A., Grün, D., Poy, M. N., Wolf, R., Rosenberg, L., Epstein, E. J., MacMenamin, P., da Piedade, I., Gunsalus, K. C., Stoffel, M., et al. (2005) · Nature Genetics

MicroRNA in disease regulationPlant Molecular Biology Research

Cited by 4,603

Silencing of microRNAs in vivo with ‘antagomirs’

Krützfeldt, J., Rajewsky, N., Braich, R., Rajeev, K. G., Tuschl, T., Manoharan, M., & Stoffel, M. (2005) · Nature

MicroRNA in disease regulationRNA Interference and Gene Delivery

Cited by 3,949

Widespread changes in protein synthesis induced by microRNAs

Selbach, M., Schwanhäusser, B., Thierfelder, N., Fang, Z., Khanin, R., & Rajewsky, N. (2008) · Nature

MicroRNA in disease regulationRNA and protein synthesis mechanisms

Cited by 3,429

miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades

Friedländer, M. R., Mackowiak, S. D., Li, N., Chen, W., & Rajewsky, N. (2012) · Nucleic Acids Research

MicroRNA in disease regulationGenomics and Phylogenetic Studies

Cited by 3,207

circRNA biogenesis competes with pre-mRNA splicing

Ashwal-Fluss, R., Meyer, M., Pamudurti, N. R., Ivanov, A., Bartok, O., Hanan, M., Evantal, N., Memczak, S., Rajewsky, N., & Kadener, S. (2014) · Molecular Cell

Circular RNAs in diseasesRNA Research and Splicing

Cited by 3,083

Circular RNAs in the Mammalian Brain Are Highly Abundant, Conserved, and Dynamically Expressed

Rybak-Wolf, A., Stottmeister, C., Glažar, P., Jens, M., Pino, N., Giusti, S., Hanan, M., Behm, M., Bartok, O., Ashwal-Fluss, R., et al. (2015) · Molecular Cell

Circular RNAs in diseasesRNA Research and Splicing

Cited by 2,423

Circ-ZNF609 is a circular RNA that can be translated and functions in myogenesis

Legnini, I., Di Timoteo, G., Rossi, F., Morlando, M., Briganti, F., Sthandier, O., Fatica, A., Santini, T., Andronache, A., Wade, M., et al. (2017) · Molecular Cell

Circular RNAs in diseasesRNA Research and Splicing

Cited by 2,173

A pancreatic islet-specific microRNA regulates insulin secretion

Poy, M. N., Eliasson, L., Krutzfeldt, J., Kuwajima, S., Ma, X., MacDonald, P. E., Pfeffer, S., Tuschl, T., Rajewsky, N., Rorsman, P., et al. (2004) · Nature

Pancreatic function and diabetesMicroRNA in disease regulation

Cited by 2,102

Translation of CircRNAs

Pamudurti, N. R., Bartok, O., Jens, M., Ashwal-Fluss, R., Stottmeister, C., Ruhe, L., Hanan, M., Wyler, E., Perez-Hernandez, D., Ramberger, E., et al. (2017) · Molecular Cell

Circular RNAs in diseasesRNA and protein synthesis mechanisms

Cited by 1,810

PAGA: graph abstraction reconciles clustering with trajectory inference through a topology preserving map of single cells

Wolf, F. A., Hamey, F. K., Plass, M., Solana, J., Dahlin, J. S., Göttgens, B., Rajewsky, N., Simon, L., & Theis, F. J. (2019) · Genome Biology

Single-cell and spatial transcriptomicsTopological and Geometric Data Analysis

Cited by 1,698

The evolution of gene regulation by transcription factors and microRNAs

Chen, K., & Rajewsky, N. (2007) · Nature Reviews Genetics

Plant Molecular Biology ResearchChromosomal and Genetic Variations

Cited by 1,547

Severe COVID-19 Is Marked by a Dysregulated Myeloid Cell Compartment

Schulte-Schrepping, J., Reusch, N., Paclik, D., Baßler, K., Schlickeiser, S., Zhang, B., Krämer, B., Krammer, T., Brumhard, S., Bonaguro, L., et al. (2020) · Cell

COVID-19 Clinical Research StudiesSARS-CoV-2 and COVID-19 Research

Cited by 1,461

Loss of a mammalian circular RNA locus causes miRNA deregulation and affects brain function

Piwecka, M., Glažar, P., Hernandez-Miranda, L. R., Memczak, S., Wolf, S. A., Rybak-Wolf, A., Filipchyk, A., Klironomos, F., Cerda Jara, C. A., Fenske, P., et al. (2017) · Science

Circular RNAs in diseasesRNA Research and Splicing

Cited by 1,210

Swarm Learning for decentralized and confidential clinical machine learning

Warnat-Herresthal, S., Schultze, H., Shastry, K. L., Manamohan, S., Mukherjee, S., Garg, V., Sarveswara, R., Händler, K., Pickkers, P., Aziz, N. A., et al. (2021) · Nature

Privacy-Preserving Technologies in DataBlockchain Technology Applications and Security

Cited by 884

Transcriptome-wide Analysis of Regulatory Interactions of the RNA-Binding Protein HuR

Lebedeva, S., Jens, M., Theil, K., Schwanhäusser, B., Selbach, M., Landthaler, M., & Rajewsky, N. (2011) · Molecular Cell

RNA Research and SplicingRNA regulation and disease

Cited by 716

Cell-type-specific signatures of microRNAs on target mRNA expression

Sood, P., Krek, A., Zavolan, M., Macino, G., & Rajewsky, N. (2006) · Proceedings of the National Academy of Sciences

MicroRNA in disease regulationRNA Research and Splicing

Cited by 650

Identification and characterization of circular RNAs As a new class of putative biomarkers in human blood

Memczak, S., Papavasileiou, P., Peters, O., & Rajewsky, N. (2015) · PLoS ONE

Circular RNAs in diseasesRNA Research and Splicing

Cited by 639

Cell type atlas and lineage tree of a whole complex animal by single-cell transcriptomics

Plass, M., Solana, J., Wolf, F. A., Ayoub, S., Misios, A., Glažar, P., Obermayer, B., Theis, F. J., Kocks, C., & Rajewsky, N. (2018) · Science

Single-cell and spatial transcriptomicsPlanarian Biology and Electrostimulation

Cited by 474

Natural selection on human microRNA binding sites inferred from SNP data

Chen, K., & Rajewsky, N. (2006) · Nature Genetics

Genetic Associations and EpidemiologyEvolution and Genetic Dynamics

Cited by 469

MicroRNA profiling of the murine hematopoietic system

Monticelli, S., Ansel, K. M., Xiao, C., Socci, N. D., Krichevsky, A. M., Thai, T.-H., Rajewsky, N., Marks, D. S., Sander, C., Rajewsky, K., et al. (2005) · Genome Biology

MicroRNA in disease regulationPlant Molecular Biology Research

Cited by 436

Paternal Diet Defines Offspring Chromatin State and Intergenerational Obesity

Öst, A., Lempradl, A., Casas, E., Weigert, M., Tiko, T., Deniz, M., Pantano, L., Boenisch, U., Itskov, P. M., Stoeckius, M., et al. (2014) · Cell

Epigenetics and DNA MethylationBirth, Development, and Health

Cited by 406

Single-cell and spatial transcriptomics: deciphering brain complexity in health and disease

Piwecka, M., Rajewsky, N., & Rybak-Wolf, A. (2023) · Nature Reviews Neurology

Single-cell and spatial transcriptomicsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 320

Unambiguous Identification of miRNA:Target Site Interactions by Different Types of Ligation Reactions

Grosswendt, S., Filipchyk, A., Manzano, M., Klironomos, F., Schilling, M., Herzog, M., Gottwein, E., & Rajewsky, N. (2014) · Molecular Cell

MicroRNA in disease regulationRNA Research and Splicing

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