Yang, Ka

Development of the first small molecule histone deacetylase 6 (HDAC6) degraders

Yang, K., Song, Y., Xie, H., Wu, H., Wu, Y.-T., Leisten, E. D., & Tang, W. (2018) · Bioorganic & Medicinal Chemistry Letters

Protein Degradation and InhibitorsHistone Deacetylase Inhibitors Research

Cited by 190

Development of Multifunctional Histone Deacetylase 6 Degraders with Potent Antimyeloma Activity

Wu, H., Yang, K., Zhang, Z., Leisten, E. D., Li, Z., Xie, H., Liu, J., Smith, K. A., Novakova, Z., Barinka, C., et al. (2019) · Journal of Medicinal Chemistry

Protein Degradation and InhibitorsHistone Deacetylase Inhibitors Research

Cited by 180

Development of Selective Histone Deacetylase 6 (HDAC6) Degraders Recruiting Von Hippel–Lindau (VHL) E3 Ubiquitin Ligase

Yang, K., Wu, H., Zhang, Z., Leisten, E. D., Nie, X., Liu, B., Wen, Z., Zhang, J., Cunningham, M. D., & Tang, W. (2020) · ACS Medicinal Chemistry Letters

Protein Degradation and InhibitorsHistone Deacetylase Inhibitors Research

Cited by 124

Development of selective small molecule MDM2 degraders based on nutlin

Wang, B., Wu, S., Liu, J., Yang, K., Xie, H., & Tang, W. (2019) · European Journal of Medicinal Chemistry

Protein Degradation and InhibitorsCancer-related Molecular Pathways

Cited by 77

Human and mouse proteomics reveals the shared pathways in Alzheimer’s disease and delayed protein turnover in the amyloidome

Yarbro, J. M., Han, X., Dasgupta, A., Yang, K., Liu, D., Shrestha, H. K., Zaman, M., Wang, Z., Yu, K., Lee, D. G., et al. (2025) · Nature Communications

Alzheimer's disease research and treatmentsAdvanced Proteomics Techniques and Applications

Cited by 41