Iwatsubo, Takeshi

Enhanced Accumulation of Phosphorylated α-Synuclein and Elevated β-Amyloid 42/40 Ratio Caused by Expression of the Presenilin-1 ΔT440 Mutant Associated with Familial Lewy Body Disease and Variant Alzheimer's Disease

Kaneko, H., Kakita, A., Kasuga, K., Nozaki, H., Ishikawa, A., Miyashita, A., Kuwano, R., Ito, G., Iwatsubo, T., Takahashi, H., et al. (2007) · The Journal of Neuroscience

Alzheimer's disease research and treatmentsParkinson's Disease Mechanisms and Treatments

Cited by 44

Alterations in human tau transcripts correlate with those of neurofilament in sporadic tauopathies

Umeda, Y., Taniguchi, S., Arima, K., Piao, Y.-S., Takahashi, H., Iwatsubo, T., Mann, D., & Hasegawa, M. (2004) · Neuroscience Letters

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 39

Amyloid β Protein in Plasma as a Diagnostic Marker for Alzheimer’s Disease

Iwatsubo, T. (1998) · Neurobiology of Aging

Alzheimer's disease research and treatmentsMedicinal Plants and Neuroprotection

Cited by 37

Semagacestat for Treatment of Alzheimer's Disease

Doody, R. S., Aisen, P. S. S., & Iwatsubo, T. (2013) · New England Journal of Medicine

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 30

Phosphorylation of Rab29 at Ser185 regulates its localization and role in the lysosomal stress response in concert with LRRK2

Komori, T., Kuwahara, T., Fujimoto, T., Sakurai, M., Koyama-Honda, I., Fukuda, M., & Iwatsubo, T. (2023) · Journal of Cell Science

Cellular transport and secretionParkinson's Disease Mechanisms and Treatments

Cited by 11

Inhibitory Roles of Apolipoprotein E Christchurch Astrocytes in Curbing Tau Propagation Using Human Pluripotent Stem Cell-Derived Models

Murakami, R., Watanabe, H., Hashimoto, H., Kashiwagi-Hakozaki, M., Hashimoto, T., Karch, C. M., the Dominantly Inherited Alzheimer Network (DIAN), Iwatsubo, T., & Okano, H. (2024) · The Journal of Neuroscience

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 9

Role of apolipoprotein E in β-amyloidogenesis: Isoform-specific effects on protofibril to fibril conversion of Aβ in vitro and brain Aβ deposition in vivo.

Hori, Y., Hashimoto, T., Nomoto, H., Hyman, B. T., & Iwatsubo, T. (2018) · Journal of Biological Chemistry

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 9

Association of rare APOE missense variants with Alzheimer's disease in the Japanese population

Miyashita, A., Obinata, A., Hara, N., Mitsumori, R., Kaneda, D., Hashizume, Y., Sano, T., Takao, M., Gabdulkhaev, R., Tada, M., et al. (2025) · Journal of Alzheimer’s Disease

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 5