Ernst, Carl

Sequencing Chromosomal Abnormalities Reveals Neurodevelopmental Loci that Confer Risk across Diagnostic Boundaries

Talkowski, M. E., Rosenfeld, J. A., Blumenthal, I., Pillalamarri, V., Chiang, C., Heilbut, A., Ernst, C., Hanscom, C., Rossin, E., Lindgren, A. M., et al. (2012) · Cell

Genomic variations and chromosomal abnormalitiesGenetics and Neurodevelopmental Disorders

Cited by 577

Global Brain Gene Expression Analysis Links Glutamatergic and GABAergic Alterations to Suicide and Major Depression

Sequeira, A., Mamdani, F., Ernst, C., Vawter, M. P., Bunney, W. E., Lebel, V., Rehal, S., Klempan, T., Gratton, A., Benkelfat, C., et al. (2009) · PLoS ONE

Treatment of Major DepressionSuicide and Self-Harm Studies

Cited by 388

Antidepressant effects of exercise: Evidence for an adult-neurogenesis hypothesis?

Ernst, C., Olson, A. K., Pinel, J. P. J., Lam, R. W., & Christie, B. R. (2006) · Journal of Psychiatry and Neuroscience

Neurogenesis and neuroplasticity mechanismsTreatment of Major Depression

Cited by 322

Astrocytic abnormalities and global DNA methylation patterns in depression and suicide

Nagy, C., Suderman, M., Yang, J., Szyf, M., Mechawar, N., Ernst, C., & Turecki, G. (2015) · Molecular Psychiatry

Epigenetics and DNA MethylationTreatment of Major Depression

Cited by 301

The neurodevelopmental origins of suicidal behavior

Turecki, G., Ernst, C., Jollant, F., Labonté, B., & Mechawar, N. (2012) · Trends in Neurosciences

Suicide and Self-Harm StudiesStress Responses and Cortisol

Cited by 299

Altered expression of genes involved in ATP biosynthesis and GABAergic neurotransmission in the ventral prefrontal cortex of suicides with and without major depression

Klempan, T. A., Sequeira, A., Canetti, L., Lalovic, A., Ernst, C., ffrench-Mullen, J., & Turecki, G. (2009) · Molecular Psychiatry

Suicide and Self-Harm StudiesTreatment of Major Depression

Cited by 294

Assessment of 2q23.1 microdeletion syndrome implicates MBD5 as a single causal locus of intellectual disability, epilepsy, and autism spectrum disorder

Talkowski, M. E., Mullegama, S. V., Rosenfeld, J. A., van Bon, B. W. M., Shen, Y., Repnikova, E. A., Gastier-Foster, J., Thrush, D. L., Kathiresan, S., Ruderfer, D. M., et al. (2011) · The American Journal of Human Genetics

Genomic variations and chromosomal abnormalitiesGenetics and Neurodevelopmental Disorders

Cited by 249

Alternative Splicing, Methylation State, and Expression Profile of Tropomyosin-Related Kinase B in the Frontal Cortex of Suicide Completers

Ernst, C., Deleva, V., Deng, X., Sequeira, A., Pomarenski, A., Klempan, T., Ernst, N., Quirion, R., Gratton, A., Szyf, M., et al. (2009) · Archives of General Psychiatry

Suicide and Self-Harm StudiesTreatment of Major Depression

Cited by 235

Association of a history of child abuse with impaired myelination in the anterior cingulate cortex: convergent epigenetic, transcriptional, and morphological evidence

Lutz, P.-E., Tanti, A., Gasecka, A., Barnett-Burns, S., Kim, J. J., Zhou, Y., Chen, G. G., Wakid, M., Shaw, M., Almeida, D., et al. (2017) · American Journal of Psychiatry

Child Abuse and TraumaEpigenetics and DNA Methylation

Cited by 203

Epigenetic regulation of BDNF expression according to antidepressant response

Lopez, J. P., Mamdani, F., Labonte, B., Beaulieu, M.-M., Yang, J. P., Berlim, M. T., Ernst, C., & Turecki, G. (2013) · Molecular Psychiatry

Treatment of Major DepressionEpigenetics and DNA Methylation

Cited by 146

Transcriptional consequences of 16p11.2 deletion and duplication in mouse cortex and multiplex autism families

Blumenthal, I., Ragavendran, A., Erdin, S., Klei, L., Sugathan, A., Guide, J. R., Manavalan, P., Zhou, J. Q., Wheeler, V. C., Levin, J. Z., et al. (2014) · The American Journal of Human Genetics

Genomic variations and chromosomal abnormalitiesGenetics and Neurodevelopmental Disorders

Cited by 145

Proliferation and differentiation deficits are a major convergence point for neurodevelopmental disorders

Ernst, C. (2016) · Trends in Neurosciences

Genetics and Neurodevelopmental DisordersNeurogenesis and neuroplasticity mechanisms

Cited by 145

Histone methylation and decreased expression of TrkB.T1 in orbital frontal cortex of suicide completers

Ernst, C., Chen, E. S., & Turecki, G. (2009) · Molecular Psychiatry

Suicide and Self-Harm StudiesEpigenetics and DNA Methylation

Cited by 98

Regulation of a Truncated Form of Tropomyosin-Related Kinase B (TrkB) by Hsa-miR-185* in Frontal Cortex of Suicide Completers

Maussion, G., Yang, J., Yerko, V., Barker, P., Mechawar, N., Ernst, C., & Turecki, G. (2012) · PLoS ONE

MicroRNA in disease regulationSuicide and Self-Harm Studies

Cited by 91

The epigenetic effects of antidepressant treatment on human prefrontal cortex BDNF expression

Chen, E. S., Ernst, C., & Turecki, G. (2011) · The International Journal of Neuropsychopharmacology

Treatment of Major DepressionEpigenetics and DNA Methylation

Cited by 88

Human iPSC-derived Down syndrome astrocytes display genome-wide perturbations in gene expression, an altered adhesion profile, and increased cellular dynamics

Ponroy Bally, B., Farmer, W. T., Jones, E. V., Jessa, S., Kacerovsky, J. B., Mayran, A., Peng, H., Lefebvre, J. L., Drouin, J., Hayer, A., et al. (2020) · Human Molecular Genetics

Down syndrome and intellectual disability researchGenetics and Neurodevelopmental Disorders

Cited by 49