Cramer, Robert A.

mTOR- and HIF-1α–mediated aerobic glycolysis as metabolic basis for trained immunity

Cheng, S.-C., Quintin, J., Cramer, R. A., Shepardson, K. M., Saeed, S., Kumar, V., Giamarellos-Bourboulis, E. J., Martens, J. H. A., Rao, N. A., Aghajanirefah, A., et al. (2014) · Science

Immune responses and vaccinationsImmune cells in cancer

Cited by 2,224

Transcriptional Regulation of Chemical Diversity in Aspergillus fumigatus by LaeA

Perrin, R. M., Fedorova, N. D., Bok, J. W., Cramer, R. A., Wortman, J. R., Kim, H. S., Nierman, W. C., & Keller, N. P. (2007) · PLoS Pathogens

Microbial Natural Products and BiosynthesisFungal and yeast genetics research

Cited by 352

A Sterol-Regulatory Element Binding Protein Is Required for Cell Polarity, Hypoxia Adaptation, Azole Drug Resistance, and Virulence in Aspergillus fumigatus

Willger, S. D., Puttikamonkul, S., Kim, K.-H., Burritt, J. B., Grahl, N., Metzler, L. J., Barbuch, R., Bard, M., Lawrence, C. B., & Cramer, R. A. (2008) · PLoS Pathogens

Fungal and yeast genetics researchAntifungal resistance and susceptibility

Cited by 345

Harnessing calcineurin as a novel anti-infective agent against invasive fungal infections.

Steinbach, W. J., Reedy, J. L., Cramer, R. A., Perfect, J. R., & Heitman, J. (2007) · Nature Reviews Microbiology

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 313

Calcineurin Controls Growth, Morphology, and Pathogenicity in Aspergillus fumigatus

Steinbach, W. J., Cramer, R. A., Perfect, B. Z., Asfaw, Y. G., Sauer, T. C., Najvar, L. K., Kirkpatrick, W. R., Patterson, T. F., Benjamin, D. K., Heitman, J., et al. (2006) · Eukaryotic Cell

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 264

In vivo Hypoxia and a Fungal Alcohol Dehydrogenase Influence the Pathogenesis of Invasive Pulmonary Aspergillosis

Grahl, N., Puttikamonkul, S., Macdonald, J. M., Gamcsik, M. P., Ngo, L. Y., Hohl, T. M., & Cramer, R. A. (2011) · PLoS Pathogens

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 217

SREBP Coordinates Iron and Ergosterol Homeostasis to Mediate Triazole Drug and Hypoxia Responses in the Human Fungal Pathogen Aspergillus fumigatus

Blatzer, M., Barker, B. M., Willger, S. D., Beckmann, N., Blosser, S. J., Cornish, E. J., Mazurie, A., Grahl, N., Haas, H., & Cramer, R. A. (2011) · PLoS Genetics

Fungal and yeast genetics researchAntifungal resistance and susceptibility

Cited by 175

Calcineurin Target CrzA Regulates Conidial Germination, Hyphal Growth, and Pathogenesis of Aspergillus fumigatus

Cramer, R. A., Perfect, B. Z., Pinchai, N., Park, S., Perlin, D. S., Asfaw, Y. G., Heitman, J., Perfect, J. R., & Steinbach, W. J. (2008) · Eukaryotic Cell

Fungal and yeast genetics researchAntifungal resistance and susceptibility

Cited by 172

Diverse Regulation of the CreA Carbon Catabolite Repressor in Aspergillus nidulans

Ries, L. N. A., Beattie, S. R., Espeso, E. A., Cramer, R. A., & Goldman, G. H. (2016) · Genetics

Fungal and yeast genetics researchBacterial Genetics and Biotechnology

Cited by 162

IL-1α Signaling Is Critical for Leukocyte Recruitment after Pulmonary Aspergillus fumigatus Challenge

Caffrey, A. K., Lehmann, M. M., Zickovich, J. M., Espinosa, V., Shepardson, K. M., Watschke, C. P., Hilmer, K. M., Thammahong, A., Barker, B. M., Rivera, A., et al. (2015) · PLOS Pathogens

Antifungal resistance and susceptibilityInflammasome and immune disorders

Cited by 132

Transcriptomic and proteomic analyses of the Aspergillus fumigatus hypoxia response using an oxygen-controlled fermenter

Barker, B. M., Kroll, K., Vödisch, M., Mazurie, A., Kniemeyer, O., & Cramer, R. A. (2012) · BMC Genomics

Fungal and yeast genetics researchAntifungal resistance and susceptibility

Cited by 127

Central Role of the Trehalose Biosynthesis Pathway in the Pathogenesis of Human Fungal Infections: Opportunities and Challenges for Therapeutic Development

Thammahong, A., Puttikamonkul, S., Perfect, J. R., Brennan, R. G., & Cramer, R. A. (2017) · Microbiology and Molecular Biology Reviews

Fungal and yeast genetics researchAntifungal resistance and susceptibility

Cited by 125

Heterogeneity among Isolates Reveals that Fitness in Low Oxygen Correlates with Aspergillus fumigatus Virulence

Kowalski, C. H., Beattie, S. R., Fuller, K. K., McGurk, E. A., Tang, Y.-W., Hohl, T. M., Obar, J. J., & Cramer, R. A. (2016) · mBio

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 123

HacA-Independent Functions of the ER Stress Sensor IreA Synergize with the Canonical UPR to Influence Virulence Traits in Aspergillus fumigatus

Feng, X., Krishnan, K., Richie, D. L., Aimanianda, V., Hartl, L., Grahl, N., Powers-Fletcher, M. V., Zhang, M., Fuller, K. K., Nierman, W. C., et al. (2011) · PLoS Pathogens

Endoplasmic Reticulum Stress and DiseaseFungal and yeast genetics research

Cited by 112

Calcineurin Inhibition or Mutation Enhances Cell Wall Inhibitors against Aspergillus fumigatus

Steinbach, W. J., Cramer, R. A., Perfect, B. Z., Henn, C., Nielsen, K., Heitman, J., & Perfect, J. R. (2007) · Antimicrobial Agents and Chemotherapy

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 108

Compartment-Specific and Sequential Role of MyD88 and CARD9 in Chemokine Induction and Innate Defense during Respiratory Fungal Infection

Jhingran, A., Kasahara, S., Shepardson, K. M., Junecko, B. A. F., Heung, L. J., Kumasaka, D. K., Knoblaugh, S. E., Lin, X., Kazmierczak, B. I., Reinhart, T. A., et al. (2015) · PLOS Pathogens

Immune Response and InflammationAntifungal resistance and susceptibility

Cited by 108

Sterilizing immunity in the lung relies on targeting fungal apoptosis-like programmed cell death

Shlezinger, N., Irmer, H., Dhingra, S., Beattie, S. R., Cramer, R. A., Braus, G. H., Sharon, A., & Hohl, T. M. (2017) · Science

Antifungal resistance and susceptibilityNeutrophil, Myeloperoxidase and Oxidative Mechanisms

Cited by 105

Filamentous fungal carbon catabolite repression supports metabolic plasticity and stress responses essential for disease progression

Beattie, S. R., Mark, K. M. K., Thammahong, A., Ries, L. N. A., Dhingra, S., Caffrey-Carr, A. K., Cheng, C., Black, C. C., Bowyer, P., Bromley, M. J., et al. (2017) · PLOS Pathogens

Fungal and yeast genetics researchAntifungal resistance and susceptibility

Cited by 103

Aspergillus fumigatus mitochondrial electron transport chain mediates oxidative stress homeostasis, hypoxia responses and fungal pathogenesis

Grahl, N., Dinamarco, T. M., Willger, S. D., Goldman, G. H., & Cramer, R. A. (2012) · Molecular Microbiology

Fungal and yeast genetics researchMitochondrial Function and Pathology

Cited by 99

Myeloid Derived Hypoxia Inducible Factor 1-alpha Is Required for Protection against Pulmonary Aspergillus fumigatus Infection

Shepardson, K. M., Jhingran, A., Caffrey, A., Obar, J. J., Suratt, B. T., Berwin, B. L., Hohl, T. M., & Cramer, R. A. (2014) · PLoS Pathogens

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 79

Phylogenomic analysis of non-ribosomal peptide synthetases in the genus Aspergillus

Cramer, R. A., Stajich, J. E., Yamanaka, Y., Dietrich, F. S., Steinbach, W. J., & Perfect, J. R. (2006) · Gene

Microbial Natural Products and BiosynthesisFungal and yeast genetics research

Cited by 66

Aspergillus fumigatus Photobiology Illuminates the Marked Heterogeneity between Isolates

Fuller, K. K., Cramer, R. A., Zegans, M. E., Dunlap, J. C., & Loros, J. J. (2016) · mBio

Fungal and yeast genetics researchAntifungal resistance and susceptibility

Cited by 55

Cloning of a Gene Encoding an Alt a 1 Isoallergen Differentially Expressed by the Necrotrophic Fungus Alternaria brassicicola during Arabidopsis Infection

Cramer, R. A., & Lawrence, C. B. (2003) · Applied and Environmental Microbiology

Plant Pathogens and Fungal DiseasesFungal and yeast genetics research

Cited by 41

Protein Kinase A and High-Osmolarity Glycerol Response Pathways Cooperatively Control Cell Wall Carbohydrate Mobilization in Aspergillus fumigatus

de Assis, L. J., Manfiolli, A., Mattos, E., Fabri, J. H. T. M., Malavazi, I., Jacobsen, I. D., Brock, M., Cramer, R. A., Thammahong, A., Hagiwara, D., et al. (2018) · mBio

Fungal and yeast genetics researchAntifungal resistance and susceptibility

Cited by 38